Results 51 to 60 of about 16,414 (200)

Microbiome-gut-brain axis and toll-like receptors in parkinson\u2019s disease [PDF]

, 2018
Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy, which involves all districts of the brain-gut axis, including the central, autonomic and enteric nervous systems.
Caputi, Valentina, Giron, Maria Cecilia
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MicroRNA-494-3p alleviates inflammatory response in sepsis by targeting TLR6.

European review for medical and pharmacological sciences, 2019
To clarify whether microRNA-494-3p could exert an anti-inflammation effect by suppressing the expression of toll-like receptor 6 (TLR6), thus inhibiting the development of sepsis.Plasma levels of microRNA-494-3p and TLR6 in sepsis patients and healthy controls were determined by quantitative real-time polymerase chain reaction (qRT-PCR).
Wang, H.-F., Li, Y., Wang, Y.-Q., Li, H.-J., Dou, L.   +4 more
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Association between Toll-Like Receptor Gene Cluster (TLR6, TLR1, and TLR10) and Prostate Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2007
Abstract Background: Chronic inflammation may be a risk factor for prostate cancer. Previously, we found significant associations between single nucleotide polymorphisms (SNPs) and haplotypes in Toll-like receptor (TLR) 4 and the risk of prostate cancer.
Chen, Yen-Ching, Giovannucci, Edward, Kraft, Peter, Lazarus, Ross, Hunter, David J.   +4 more
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Toll-like receptor 6 inhibits colorectal cancer progression by suppressing NF-κB signaling

Heliyon
Background: Toll-like receptors (TLRs) are implicated in the pathogenesis and progression of inflammation-associated cancers, except their role in regulating innate immunity.
Lina Ma, Yancun Yin, Zhenhai Yu, Ning Xu, Lianhuan Ma, Weiwei Qiao, Xiaowen Zhen, Fan Yang, Naili Zhang, Yue Yu   +9 more
doaj   +1 more source

Polymorphism of genes of Toll-like receptors as a potential factor of predisposition to tuberculosis

Туберкулез и болезни лёгких, 2018
The objective of the study: to detect genotypes and frequency of gene alleles of Toll-receptors (Arg753Gln – for TLR2; Phe412Leu – for TLR3; Asp299Gly – for TLR4; Ser249Pro – for TLR6) among respiratory tuberculosis patients in Zabaykalsky Kray.Subjects ...
E. S. Bogodukhovа, E. E. Bаyke
doaj   +1 more source

Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism [PDF]

, 2015
© 2015 Wiley Periodicals, Inc. Acknowledgement Grant sponsor: State of Lower Saxony-Israel Research Cooperation; Grant number: ZN2035; Grant sponsor:German Research Council; Grant number: SFB/TRR43 and FOR1336; Grant sponsor: Parkinson UK; Grant number ...
Akarasereenont, Amedei, Angstwurm, Balachandra, Bermejo, Bettelli, Boucheron, Brenner, Brück, Byrd, Chatterjee, Chiang, Coles, Cossburn, Cuzzocrea, Cuzzocrea, Das Sarma, Doyle, Dugo, Fischer, Fitzner, George, Ghoreschi, Goldmann, Gorina, Gray, Haider, Hanamsagar, Hanisch, Hanisch, Hanisch, Hoffmann, Hong, Horwood, Jaleel, Jefferies, Kahlenberg, Kann, Kawai, Kelly, Khan, Krady, Langer-Gould, Lee, Lehmann, Lehmann-Horn, Lehnardt, Levitzki, Li, Lin, Liu, Liu, Lopez-Talavera, Mangla, Marzocco, Mattsson, Mauro, McDonald, McGeer, Mehta, Mijovic, Mohamed, Moore, Muelas-Serrano, Mukhopadhyay, Murray, Novogrodsky, Perry, Prinz, Raghavan, Ramdas, Regen, Rossum, Ruetten, Sagara, Scheffel, Schmidt, Schweingruber, Simmons, Soltoff, Spitzer, Stewart, Terada, Turpaev, Tönges, Wang, Wang, Weber, Weber, Wüst, Xiao, Zhang, Zorn   +92 more
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Expression of Toll-like receptors in nasal epithelium in allergic rhinitis [PDF]

, 2015
Toll-like receptors (TLRs) are important in barrier homeostasis, but their role in airborne allergies is not fully understood. The aim was to evaluate baseline and allergen-induced expression of TLR proteins in nasal epithelium during allergic rhinitis ...
Haglund, Caj, Hagstrom, Jaana, Joenvaara, Sakari, Lehtonen, Mikko, Mattila, Pirkko, Parviainen, Ville, Renkonen, Jutta, Renkonen, Risto, Toppila-Salmi, Sanna   +8 more
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Altered Toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma [PDF]

, 2017
Toll-like receptors (TLRs) have been widely investigated due to their importance in the inflammatory response and possible links to tumor promotion/regression and prognosis.
Akira, Antonelli, Bar-Eli, Bosselut, Breckpot, Brugge, Califano, Chaturvedi, Chen, Chinnaiyan, Choi, Chu, Cullen, Dalianis, Davila, Duan, Frokiaer, Furcht, Gerstein, Guo, Gupta, Hagstrom, Hasan, Hornef, Huang, Ilardi, Jagodzinski, Johnston, Kumar, Laimins, Larusso, Li, Liu, Marcotte, Maxfield, Medzhitov, Mendiola, Moscicki, Moscicki, Moyes, Naglik, Psyrri, Read, Rusan, Sasser, Schaller, Schwabe, Shao, Shinohara, Smith, Sturgis, Tapping, van der Burg, Watanabe, Wilson, Zehbe, Zhang   +56 more
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TLR6 Gene Polymorphism, Sequence Analysis, and Phylogenetic Tree in Susscrofa

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY, 2017
TLRs (Toll like receptors) gene have a very important role in early defense against invading pathogens, still we do not have sufficient literature available about them specially TLR6 gene in swine. The current study deals with the characteristic polymorphic, sequencing and evolutionary pattern of TLR6 gene in swine.
Nandani Kumari, L. B. Singh
openaire   +1 more source

Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]

, 2018
open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of

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