Results 151 to 160 of about 38,400 (238)

The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity

MedComm, Volume 7, Issue 7, July 2026.
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng, Qilong Li, Ning Jiang, Qijun Chen   +3 more
wiley   +1 more source

Postbiotics: An Overview and Recommendations for Improved Reporting

Molecular Nutrition &Food Research, Volume 70, Issue 14, 29 July 2026.
Human clinical trials of postbiotics and corresponding preclinical evidence were evaluated. Key reporting gaps identified included inconsistent terminology, incomplete inactivation method reporting, variable dosing information, insufficient quality‐control data, and inadequate taxonomic characterization.
Mehreen Anjum, Arthur C. Ouwehand
wiley   +1 more source

TLR9/MyD88/NF-κB signaling mediates mental stress-induced exacerbation of psoriasis through immune dysregulation in a mouse model. [PDF]

PLoS One
Song Q, Li D, Yuan Z, Zhang C, Wang J, Liao F, Xu P, Xiao Q.   +7 more
europepmc   +1 more source

Coding and Noncoding Uterine Small Extracellular Vesicle Content Differs in the Early Stages of Pregnancies Produced by Artificial Insemination and In Vitro Fertilization in Cattle

Molecular Reproduction and Development, Volume 93, Issue 7, July 2026.
ABSTRACT Establishing a successful pregnancy relies on effective communication between the mother and fetus. Small extracellular vesicles (sEVs) are pivotal in facilitating intercellular communication, transferring messenger RNA (mRNA), noncoding RNA (ncRNA), and proteins. Considering the prevalence of in vitro fertilization (IVF) in bovine production,
Amanda de Oliveira Furlan, Alessandra Bridi, Jéssica Nora Drum, Liza Margareth Medeiros de Carvalho Sousa, Mariana Cordeiro Almeida, Juliana de Souza Felix, Luana Araujo Zutin, Isabelle Alexandrino dos Santos, Flávia Regina Florencio de Athayde, Natália Francisco Scaramele, Camila Azzolin de Souza, Paula de Carvalho Papa Keohane, Juliano Coelho da Silveira, Roberto Sartori Filho, Danila Barreiro Campos, Flavia Lombardi Lopes   +15 more
wiley   +1 more source

TLR9-activating cholesterol azetidine derivative-assisted therapeutic vaccines for cancer immunotherapy. [PDF]

Sci Adv
Chen J, Su M, Yu B, Yang M, Wang H, Yang X, Wang J.   +6 more
europepmc   +1 more source

Computational and Experimental Development of a Novel Multi‐Epitope Vaccine Candidate Against Bovine Leukaemia Virus

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study designs a novel multi‐epitope vaccine against bovine leukaemia virus using immunoinformatics. The construct demonstrates high antigenicity, stability, and strong receptor binding, indicating its potential as an effective recombinant vaccine candidate for further experimental validation .
Yasaman Dini, Tohid Piri‐Gharaghie, Elahe Hamdi, Pegah Goodarzi, Ronak Ahmadi   +4 more
wiley   +1 more source

Mitochondrial DNA regulation of hepatic ischemia-reperfusion injury and intervention strategies. [PDF]

J Transl Med
Shen R, An P, Chen M, Lu P, Yang J, Wu L, Wang R.   +6 more
europepmc   +1 more source

Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju, Abimbola Motunrayo Folami, Saheed Sabiu, Feroz Mahomed Swalaha   +3 more
wiley   +1 more source

Sequential nanocatalytic therapy and lysosomal dysfunction for overcoming castration-resistant prostate cancer. [PDF]

Bioact Mater
Di J, Lee W, Xu Y, Kong H, Zhou F, Xu J, Chen X, Lao YH, Shao D, Xie X, Yao H, Tao Y, Li M.   +12 more
europepmc   +1 more source

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta‐Analysis of Public Transcriptional Profiling Data From the Hippocampus and Cortex

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We used a systematic meta‐analysis of public transcriptional profiling datasets to identify genes and functional gene sets that are differentially expressed ...
Eva M. Geoghegan, Megan H. Hagenauer, Erin Hernandez, Sophia Espinoza, Elizabeth I. Flandreau, Phi T. Nguyen, Adrienne N. Santiago, Mubashshir Ra’eed Bhuiyan, Sophie Mensch, Stanley J. Watson Jr., Huda Akil, René Hen   +11 more
wiley   +1 more source