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Bacterial CpG-DNA Licenses TLR9
2002The family of Toll-like receptors (TLRs) plays an important role in the innate immune response to pathogens. TLRs sense pathogen associated molecular patterns (PAMP) and lead to the stimulation of immune cells. In man, so far ten members (TLR1-10) have been reported.
S, Bauer, H, Wagner
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[TLR3c.1377, TLR9-1486, and TLR9 2848 gene polymorphisms and multiple sclerosis].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011To investigate the relationship between the gene polymorphism of TLR3c.1377,TLR9-1486,and TLR9 2848 and susceptibility to multiple sclerosis(MS)in Han people of south China.A total of 123 unrelated MS patients from South China with a clinical or laboratory definition MS according to 2005 Revisions to the McDonald Criteria were studied.
Xiaobei, Ji +3 more
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56 Aacetaminophen Hepatotoxicity Is Dependent On TLR9 and Can Be Reduced By a TLR9 Antagonist
Gastroenterology, 2008Shamail Mahmood +4 more
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TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
Immunology and Cell Biology, 2009Lisa Blum, Cynthia Leifer
exaly
TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes
EBioMedicine, 2019Kaja Żuwala +2 more
exaly