Results 211 to 220 of about 46,527 (261)

LAPF enhances lysosomal acidification to promote TLR9 and cGAS-STING-mediated antiviral immunity and attenuate HSV-1-induced neuroinflammatory pain. [PDF]

J Neuroinflammation
Kong E, Deng M, Ding R, Yang M, Li Y, Feng X, Song H, Wei H, Jiang X, Yuan H, Han C.   +10 more
europepmc   +1 more source

<i>Artemisia rupestris</i> Improves the Microbiota-Barrier Axis in DSS Colitis. [PDF]

Int J Mol Sci
Wu J, Mao X.
europepmc   +1 more source

o-Toluidine and its metabolites induce oxidative and nitrative DNA damage in human urinary bladder epithelial cells. [PDF]

Arch Toxicol
Chen HJ, Ahmed S, Cui ZG, Kimura E, Ma N, Hiraku Y.   +5 more
europepmc   +1 more source

Aquamin, a marine derived multi-mineral, attenuates toll-like receptor-mediated inflammatory responses in macrophages. [PDF]

Front Immunol
Lioudakis E, Hans S, O'Gorman DM, O'Connell S, Lucitt M.   +4 more
europepmc   +1 more source

Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy. [PDF]

Nephrol Dial Transplant
Fukao Y, Suzuki H, Nihei Y, Makita Y, Kano T, Nakayama M, Lee M, Kato R, Kihara M, Suzuki Y.   +9 more
europepmc   +1 more source

Toll-like receptor 2 coordinates induction of IL-22 in lung macrophages following organic dust-induced inflammation. [PDF]

Front Physiol
Oyewole EO, Mondal P, Jones K, McDermott C, Cunningham T, Dean LS, Barahona M, Threatt AN, Wahl MJ, Poole JA, Nordgren TM.   +10 more
europepmc   +1 more source

Activation of rabbit TLR9 by different CpG-ODN optimized for mouse and human TLR9

Comparative Immunology, Microbiology and Infectious Diseases, 2012
Synthetic CpG-oligodeoxynucleotides (CpG-ODN) are potent adjuvants that accelerate and boost antigen-specific immune responses. Toll-like receptor 9 (TLR9) is the cellular receptor for these CpG-ODN. Previous studies have shown species-specific activation of mouse TLR9 (mTLR9) and human TLR9 (hTLR9) by their optimized CpG-ODN.
Jin, Liu, Congfeng, Xu, Yi-Ling, Liu, Hanako, Matsuo, Rebecca Pe-feng, Hsieh, Jeng-Fan, Lo, Ping-Hui, Tseng, Chiun-Jye, Yuan, Yunping, Luo, Rong, Xiang, Tsung-Hsien, Chuang   +10 more
core   +4 more sources

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TLR9 in Health and Disease

International Reviews of Immunology, 2006
Toll-like receptor 9 (TLR9) is specialized for the recognition of pathogenic nucleic acids. TLR9 is expressed in intracellular compartments where it responds specifically to pathogen DNA. Several factors contribute to the ability of TLR9 to discriminate between self and foreign DNA.
Jörg Vollmer
exaly   +3 more sources

DNA Motifs Suppressing TLR9 Responses

Critical Reviews™ in Immunology, 2006
Immune cells respond to bacterial DNA containing unmethylated CpG motifs via Toll-like receptor 9 (TLR9). Given the apparent role of TLR9 in development of systemic lupus erythematosus (SLE), there is interest in the development of TLR9 inhibitors. TLR9-mediated responses are reported to be inhibited by a confusing variety of different DNA sequences ...
Trieu, Angela, Roberts, Tara L. (R17471), Dunn, Jasmyn A., Sweet, Matthew J., Stacey, Katryn J.   +4 more
openaire   +6 more sources

Expression of TLR9 within human glioblastoma

Journal of Neuro-Oncology, 2008
Immunostimulating oligonucleotides containing CpG motifs (CpG-ODN) have shown promising antitumor activity in preclinical glioma models. CpG motifs are specifically recognized by the Toll-like receptor 9 (TLR9), mainly expressed in plasmacytoid dendritic cells (pDCs) and B cells. Expression of TLR9 within human glioma samples has not been investigated.
Yannick Marie, Joelle Thillet, Michele Kujas   +2 more
exaly   +3 more sources