Results 31 to 40 of about 25,778 (287)

Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice

Nutrients, 2023
Dietary methionine restriction (MR) has been shown to decrease plasma trimethylamine-N-oxide (TMAO) levels in high-fat diet mice; however, the specific mechanism used is unknown.
Manman Lu, Yuhui Yang, Yuncong Xu, Xiaoyue Wang, Bowen Li, G. Le, Yanli Xie   +6 more
semanticscholar   +1 more source

Aerobic TMAO respiration in Escherichia coli [PDF]

Molecular Microbiology, 2007
SummaryIn the absence of oxygen, Escherichia coli can use alternative exogenous electron acceptors, including trimethylamine oxide (TMAO), to generate energy. In this study, we showed that in contrast to the other anaerobic respiratory systems, the TMAO reductase (Tor) system was expressed during both aerobiosis and anaerobiosis.
Ansaldi, Mireille, Théraulaz, Laurence, Baraquet, Claudine, Panis, Gaël, Méjean, Vincent   +4 more
openaire   +3 more sources

Connections between serum Trimethylamine N-Oxide (TMAO), a gut-derived metabolite, and vascular biomarkers evaluating arterial stiffness and subclinical atherosclerosis in children with obesity

Frontiers in Endocrinology, 2023
Introduction Childhood obesity leads to early subclinical atherosclerosis and arterial stiffness. Studying biomarkers like trimethylamine N-oxide (TMAO), linked to cardio-metabolic disorders in adults, is crucial to prevent long-term cardiovascular ...
Monica-Simina Mihuta, C. Paul, Andreea Borlea, Cristina Mihaela Roi, Denisa Pescari, Oana-Alexandra Velea-Barta, I. Mozoș, D. Stoian   +7 more
semanticscholar   +1 more source

Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes. [PDF]

, 2020
BACKGROUND:The reconstruction of metabolic networks and the three-dimensional coverage of protein structures have reached the genome-scale in the widely studied Escherichia coli K-12 MG1655 strain.
Catoiu, Edward, Fang, Xin, Heckmann, David, Mih, Nathan, Monk, Jonathan M, Palsson, Bernhard O, Yang, Laurence   +6 more
core   +2 more sources

Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells [PDF]

, 2012
The twin arginine protein transport (Tat) system translocates folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of chloroplasts.
Alami, Bartolomé, Bauer, Berks, Bernhardt, Berthelmann, Bogsch, Bolhuis, Bryson, Buchanan, Casadaban, Chan, Cline, Cline, Dabney-Smith, Dabney-Smith, de Leeuw, De Leeuw, Gohlke, Gouffi, Greene, Hashimoto-Gotoh, Heijne, Hu, Ize, Jack, Jack, Laemmli, Leake, Lee, Leive, Lu, Maegawa, Maldonado, Mori, Mori, Palmer, Palmer, Porcelli, Punginelli, Richter, Sambrook, Sargent, Sargent, Sargent, Sauvé, Silvestro, Simons, Stanley, Stevenson, Tarry, Tarry, Towbin, Walther, Wang, Weiner, Wessel, Wexler, Yen   +58 more
core   +3 more sources

From heart failure and kidney dysfunction to cardiorenal syndrome: TMAO may be a bridge

Frontiers in Pharmacology, 2023
The study of trimethylamine oxide (TMAO), a metabolite of gut microbiota, and heart failure and chronic kidney disease has made preliminary achievements and been summarized by many researchers, but its research in the field of cardiorenal syndrome is ...
Jialu Zhang, Peining Zhu, Siyu Li, Yufei Gao, Yue Xing   +4 more
semanticscholar   +1 more source

Coronary Heart Disease and TMAO Concentrations

Journal of the American College of Cardiology, 2020
We congratulate Heianza et al. ([1][1]) for their important study showing the association between a 10-year change in TMAO levels and incidence of coronary heart disease. May we kindly ask the authors to provide some additional information to help put their findings into clinical perspective?
Melissa L, Amrein, Pedro, Lopez-Ayala, Joan, Walter, Velina, Widmer, Christian, Mueller   +4 more
openaire   +2 more sources

Molecular dynamics as an approach to study prion protein misfolding and the effect of pathogenic mutations [PDF]

, 2011
Computer simulation of protein dynamics offers unique high-resolution information that complements experiment. Using experimentally derived structures of the natively folded prion protein (PrP), physically realistic dynamics and conformational changes ...
Daggett, Valerie, van der Kamp, Marc W
core   +2 more sources

Gut microbiota-dependent trimethylamine n-oxide pathway contributes to the bidirectional relationship between intestinal inflammation and periodontitis

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundIntestinal inflammation and periodontitis influence the development of each other through the bidirectional relationship. As the intestinal microbiome metabolite, trimethylamine-N-oxide (TMAO) could contribute to chronic inflammation in the gut
Qiqi Wang, Yue Sun, Yue Sun, Tianyu Zhou, Cong Jiang, Lan A, Lan A, Wenzhou Xu, Wenzhou Xu   +8 more
doaj   +1 more source

Gut Microbial Metabolism and Nonalcoholic Fatty Liver Disease. [PDF]

, 2019
The gut microbiome, the multispecies community of microbes that exists in the gastrointestinal tract, encodes several orders of magnitude more functional genes than the human genome. It also plays a pivotal role in human health, in part due to metabolism
Lynch, Susan V, Sharpton, Suzanne R, Terrault, Norah A, Yong, Germaine JM   +3 more
core   +1 more source