Shenghong Qi,1,2 Lan Liu,1,2 Shulan He,1,2 Liqun Wang,1,2 Jiangping Li,1,2 Xian Sun1,2 1School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2The Key Laboratory of Environmental Factors and ...
Qi S, Liu L, He S, Wang L, Li J, Sun X
doaj
Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model [PDF]
The transgenomic metabolic effects of exposure to either Lactobacillus paracasei or Lactobacillus rhamnosus probiotics have been measured and mapped in humanized extended genome mice (germ-free mice colonized with human baby flora).
Allison C +22 more
core +2 more sources
Introduction: Trimethylamine N-oxide (TMAO) is a metabolite produced by gut bacteria. Although increased TMAO levels have been linked to hypertension (HTN) and chronic kidney disease (CKD) with poor prognosis, no clinical studies have directly addressed ...
Jia Zhou +7 more
doaj +1 more source
Influence of polar co-solutes and salt on the hydration of lipid membranes [PDF]
The influence of the co-solutes TMAO, urea, and NaCl on the hydration repulsion between lipid membranes is investigated in a combined experimental/simulation approach.
Loche, Philip +6 more
core +1 more source
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
Identification and characterization of trimethylamine N-oxide (TMAO) demethylase and TMAO permease in Methylocella silvestris BL2. [PDF]
Methylocella silvestris, an alphaproteobacterium isolated from a forest soil, can grow on trimethylamine N-oxide (TMAO) as a sole nitrogen source; however, the molecular and biochemical mechanisms underpinning its growth remain unknown. Marker-exchange mutagenesis enabled the identification of several genes involved in TMAO metabolism, including ...
Zhu, Yijun +7 more
openaire +2 more sources
Reduction of trimethylamine N-oxide to trimethylamine by the human gut microbiota: supporting evidence for ‘metabolic retroversion’ [PDF]
Dietary sources of methylamines such as choline, trimethylamine (TMA), trimethylamine N-oxide (TMAO), phosphatidylcholine (PC) and carnitine are present in a number of foodstuffs, including meat, fish, nuts and eggs.
Chilloux, J +4 more
core +3 more sources
Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota
Background The dietary methylamines choline, carnitine, and phosphatidylcholine are used by the gut microbiota to produce a range of metabolites, including trimethylamine (TMA).
Lesley Hoyles +12 more
doaj +1 more source
Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential
Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
doaj +1 more source
Temperature dependence of the hydrogen bond network in Trimethylamine N-oxide and guanidine hydrochloride - water solutions [PDF]
We present an X-ray Compton scattering study on aqueous Trimethylamine N-oxide (TMAO) and guanidine hydrochloride solutions (GdnHCl) as a function of temperature. Independent from the concentration of the solvent, Compton profiles almost resemble results
Elbers, Mirko +10 more
core +2 more sources

