Results 21 to 30 of about 235,198 (285)

Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer's Disease Mouse Model. [PDF]

Mol Neurobiol
Zhu T, Shen F, Jia X, Zhou H, Ni W, Wang S, Wu D, Gao H, Shang Z, Zhou Y, Han J, Jin G, Dong F, Zu J, Yang X, Shi H, Zhou C, Hua F.   +17 more
europepmc   +3 more sources

Inhibition of Toll-Like Receptor 3 Relieves Osteoarthritis by Suppression of Cartilage Degradation, Nuclear Factor Kappa B-Mediated Inflammation, and Activation of Autophagy. [PDF]

Cartilage
Hou Z, Wang M, Cao S.
europepmc   +2 more sources

Toll-like receptor 3 activation enhances antitumor immune response in lung adenocarcinoma through NF-κB signaling pathway. [PDF]

Front Immunol
Li A, Luo M, Liu X, Wu H, Liu X, Zhang Z, Zhang X.   +6 more
europepmc   +3 more sources

Intratracheal instillation of graphene oxide with different diameters suppressed toll-like receptor 3-mediated lipid droplet biogenesis in lungs and livers of mice. [PDF]

Toxicol Res (Camb)
Wang Y, Tang X, Luo S, Zhang Z, Cao Y.
europepmc   +3 more sources

Inorganic Arsenic Induces Elevated p53 Levels with Altered Functionality Impacting the Expression of Toll-like Receptor 3 and Other Target Genes in Immortalized Prostate Epithelial Cells. [PDF]

Int J Mol Sci
Pacheco-Castillo NC, Gómez-Montalvo J, Olivares-Illana V, Recillas-Targa F, Tokar EJ, Avendaño-Vázquez SE, Escudero-Lourdes C.   +6 more
europepmc   +3 more sources

Toll‐Like Receptor 3: A Link between Toll‐Like Receptor, Interferon and Viruses [PDF]

Microbiology and Immunology, 2004
AbstractProduction of type I interferon (IFN‐α/β) by virus‐infected cells is the central event in their antiviral immune responses. In mammalian cells, IFN‐α/β gene transcription is induced through distinct signaling pathways by viral infection or by treatment with double‐stranded (ds) RNA, which is an intermediate of virus replication.
Misako, Matsumoto, Kenji, Funami, Hiroyuki, Oshiumi, Tsukasa, Seya   +3 more
openaire   +2 more sources

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca²⁺/CaMKII/pannexin 1-dependent signaling. [PDF]

Theranostics
Salgado M, Sepúlveda-Arriagada V, Konar-Nié M, García-Robles MA, Sáez JC.   +4 more
europepmc   +3 more sources

Polyinosinic Acid Is a Ligand for Toll-like Receptor 3 [PDF]

Journal of Biological Chemistry, 2007
Innate immune responses are critical in controlling viral infections. Viral proteins and nucleic acids have been shown to be recognized by pattern recognition receptors of the Toll-like receptor (TLR) family, triggering downstream signaling cascades that lead to cellular activation and cytokine production.
Marshall-Clarke, Stuart, Downes, Joan E., Haga, Ismar R., Bowie, Andrew G., Borrow, Persephone, Pennock, Joanne L.; id_orcid 0000-0002-8304-2905, Grencis, Richard K., Rothwell, Paul   +7 more
openaire   +4 more sources

PM2.5 increases mouse blood pressure by activating toll-like receptor 3

Ecotoxicology and Environmental Safety, 2022
Background and aims: Plenty of literature has documented that fine particulate matter (PM2.5) exposure is related to blood pressure (BP) elevation. Vascular dysfunction is the initiation of cardiovascular diseases, such as hypertension.
Jinna Zhang, Rucheng Chen, Guoqing Zhang, Yixuan Wang, Jing Peng, Renjie Hu, Ran Li, Weijia Gu, Lu Zhang, Qinghua Sun, Cuiqing Liu   +10 more
doaj   +1 more source

The Role of MEG3 in the Activation of Toll Like Receptor 3 in Prostate Cancer Cells

Sakarya Tıp Dergisi, 2021
Objective: Prostate cancer accounts for approximately 10% of new cases diagnosed in men worldwide. Toll like receptors (TLRs) play a crucial role in the progression of cancer.
Gamze Güney Eskiler, Asuman Deveci Özkan, Erhan Bezdegümeli, Merve Nur İnce, Ahmet Yasir Men, Bilge Nur Küçükakça   +5 more
doaj   +1 more source