Results 31 to 40 of about 119,102 (41)

Filarial Lymphedema Is Characterized by Antigen- Specific Th1 and Th17 Proinflammatory Responses and a Lack of Regulatory T Cells [PDF]

, 2009
Background: Lymphatic filariasis can be associated with development of serious pathology in the form of lymphedema, hydrocele, and elephantiasis in a subset of infected patients. Methods and Findings: To elucidate the role of CD4+ T cell subsets in the
A Saint André, AC Vickery, AG Hise, Angelo B. Lipira, AY Debrah, C. Karthik, CT Weaver, D Tracey, DO Freedman, DO Freedman, DO Freedman, FK Nelson, G Dreyer, Inohara, J Figueredo-Silva, J MacMicking, JS Stumhofer, K Takeda, K Wing, LI Rutitzky, LI Rutitzky, M Gavin, M Numasaki, MD Taylor, MJ McGeachy, MJ Taylor, MJ Taylor, MO Li, N Inohara, N. Pavan Kumar, NW Brattig, P Blanco, P Esterre, RB Lal, RB Lal, Ricardo Toshio Fujiwara, RT Semnani, S Babu, S Babu, S Babu, S Babu, Sajid Q. Bhat, Sanath Kumar, Subash Babu, TB Nutman, TD Kanneganti, Thomas B. Nutman, V. Kumaraswami, W Ouyang, Y Belkaid, Z Fehervari   +50 more
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Pattern recognition receptors as potential therapeutic targets in inflammatory rheumatic disease [PDF]

, 2015
The pattern recognition receptors of the innate immune system are part of the first line of defence against pathogens. However, they also have the ability to respond to danger signals that are frequently elevated during tissue damage and at sites of ...
A Baroja-Mazo, A Kuznik, A Lartigue, A Nair, A Yarilina, AM Piccinini, C Jiang, C Jin, C Ospelt, CL Baumann, CM Burns, CM Wang, CR Scanzello, CR Scanzello, D Jiang, D Loeuille, D Tang, DE Macfarlane, DH Kono, DH Sohn, DJ Connolly, E Latz, E Savarese, E Seki, F Brentano, F Hu, F Martinon, F Martinon, FG Goh, G Barreto, G Obermoser, Giselle Chamberlain, H Bernuth von, H Wardemann, HK Lee, HO Sweet, HS Youn, HY Yang, J Choi, JE Molineros, K Bobacz, K Midwood, K Neumann, K Oelke, K Schroder, K Yokota, L Bacconnier, L Sun, LA O'Neill, LE Munoz, Lisa M Mullen, LV Walle, M Carrion, M Feldmann, M Nakashima, MC Boissier, MF Roelofs, ML Santiago-Raber, ND Chamberlain, O Alvarez-Garcia, P Emery, PA Gibilisco, PS Chockalingam, PW Noble, R Baccala, R Liu-Bryan, R Liu-Bryan, R Thwaites, RC Coll, RM Pope, S Abdollahi-Roodsaz, S Abdollahi-Roodsaz, S Abdollahi-Roodsaz, S Alzabin, S Nasi, S Rakoff-Nahoum, SA Schattgen, Sandra Sacre, SL Su, SM Sacre, SM Sacre, SN Ultaigh, SY Chen, SY Lee, T Dorner, T Kawai, T Misawa, TB Geijtenbeek, TB Niewold, TH Mogensen, TH Tran, V Gagne, W Zhang, W Zhang, WJ McCormack, X Chevalier, Y Zhong   +96 more
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TLR9-based immunotherapy for the treatment of allergic diseases [PDF]

, 2017
Toll-like receptors (TLRs), a family of pattern recognition receptors expressed on many cell types of innate immunity, recognize the pathogen-associated molecular patterns of microbes.
Akira S, Ali Movahed, Farrokhi S, Hoshino K, Hossein Ali Khazaei, Kline JN, Masoud Pishjoo, Narjes Abbasirad, Nima Rezaei, Shokrollah Farrokhi, Spiegelberg HL, Sur S   +11 more
core   +1 more source

Leptospirosis renal disease: Understanding the initiation by Toll-like receptors [PDF]

, 2007
Leptospirosis is a prevalent infectious disease affecting both humans and animals worldwide. This infection is associated with occupational or recreational exposure to animals as well as contact with leptospires, particularly in flood-prone areas ...
Yang, C.-W.
core   +1 more source

Reformulating Pro-Oxidant Microglia in Neurodegeneration [PDF]

, 2019
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered a new subpopulation named ...
Alonso Bellido, Isabel María, Burguillos García, Miguel Ángel, Cruz Hernández, Luis, Espinosa Oliva, Ana María, García Domínguez, Irene, García Revilla, Juan, Herrera Carmona, Antonio José, Martínez de Pablos, Rocío, Roca Ceballos, María Angustias, Rodríguez Gómez, José Antonio, Ruiz Laza, Rocío, Santiago Pavón, Martiniano, Sarmiento Soto, Manuel, Venero Recio, José Luis   +13 more
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Pathogen Recognition and Innate Immunity [PDF]

, 2006
Microorganisms that invade a vertebrate host are initially recognized by the innate immune system through germline-encoded pattern-recognition receptors (PRRs).
Akira, Shizuo, Takeuchi, Osamu, Uematsu, Satoshi   +2 more
core   +1 more source

Toll-like receptors as modulators of intestinal barrier function / [PDF]

, 2016
BibliografiaPremi Extraordinari de Doctorat concedit pels programes de doctorat de la UAB per curs acadèmic 2016-2017Las patologías funcionales (síndrome del intestino irritable, IBS) e inflamatorias gastrointestinales (enfermedad inflamatoria intestinal,
Estévez Medina, Javier, Universitat Autònoma de Barcelona. Institut de Neurociències   +1 more
core   +1 more source

NF-{kappa}B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses [PDF]

, 2006
Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative regulators controlling diverse biological processes at the ...
Baltimore, David, Boldin, Mark P., Chang, Kuang-Jung, Taganov, Konstantin D.   +3 more
core  

Role of Toll-like receptors in development of postpartum endometritis [PDF]

, 2011
The aim of the study was to establish the association between expression of TLR1 (ligands - triacyl lipopeptides), TLR2 (ligands - lipopeptides, lipoteichoic acid, zymosan), and TLR 5 (ligand - flagellin) of cervical epithelial cells in vivo and ...
Lebedeva, O., Pakhomov, S., Samborskaya, N.   +2 more
core  

A central role for Toll-like 4 receptors in interstitial cystitis? [PDF]

, 2018
Chess-Williams, Russ, McDermott, Catherine, Sellers, Donna Jayne   +2 more
core   +1 more source