Results 41 to 50 of about 103,968 (278)
The Development of Phasic and Tonic Inhibition in the Rat Visual Cortex [PDF]
The Korean Journal of Physiology and Pharmacology, 2010 Gamma-aminobutyric acid (GABA)-ergic inhibition is important in the function of the visual cortex. In a previous study, we reported a developmental increase in GABA(A) receptor-mediated inhibition in the rat visual cortex from 3 to 5 weeks of age. Because this developmental increase is crucial to the regulation of the induction of long-term synaptic ...
Hyun-Jong, Jang +5 more
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Neurosteroids Mediate Habituation and Tonic Inhibition in the Auditory Midbrain [PDF]
Journal of Neurophysiology, 2001 Habituation of the behavioral response to a repetitive stimulus is a well-established observation in perceptual studies and is considered a basic form of nonassociative learning. There is also a long history of physiological studies suggesting that central nervous system habituation is mediated by inhibition.
Disney, A, Calford, Mike B
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Modulation of the input–output function by GABAA receptor-mediated currents in rat oculomotor nucleus motoneurons [PDF]
, 2014 The neuronal input–output function depends on recruitment threshold and gain of the firing frequency–current (f–I) relationship. These two parameters are positively correlated in ocular motoneurons (MNs) recorded in alert preparation and inhibitory ...
Carrascal Moreno, María Livia +2 more
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Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model
Frontiers in Molecular Neuroscience, 2019 Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. A reduction in neuronal inhibition mediated by γ-aminobutyric acid type A receptors (GABAARs) has been implicated in the pathophysiology of FXS.
Amit Modgil +6 more
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Protein kinase C regulates tonic GABAA receptor-mediated inhibition in the hippocampus and thalamus. [PDF]
, 2013 Tonic inhibition mediated by extrasynaptic GABAA receptors (GABAA Rs) is an important regulator of neuronal excitability. Phosphorylation by protein kinase C (PKC) provides a key mode of regulation for synaptic GABAA Rs underlying phasic inhibition ...
Bright, DP, Smart, TG
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What roles do tonic inhibition and disinhibition play in the control of motor programs?
Frontiers in Behavioral Neuroscience, 2010 Animals show periods of quiescence interspersed with periods of motor activity. In a number of invertebrate and vertebrate systems, quiescence is achieved by active suppression of motor behavior induced by sensory input or changes in internal state ...
Paul R Benjamin +2 more
doaj +1 more source
PLoS ONE, 2013 Cerebellar granule cells (CGNs) are one of many neurons that express phasic and tonic GABAergic conductances. Although it is well established that Golgi cells (GoCs) mediate phasic GABAergic currents in CGNs, their role in mediating tonic currents in ...
Marvin R Diaz +4 more
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Interaural time difference processing in the mammalian medial superior olive [PDF]
, 2008 The dominant cue for localization of low-frequency sounds are microsecond differences in the time-of-arrival of sounds at the two ears [interaural time difference (ITD)].
Behrend, Oliver +3 more
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Does Corticothalamic Feedback Control Cortical Velocity Tuning? [PDF]
, 2001 The thalamus is the major gate to the cortex and its contribution to cortical receptive field properties is well established. Cortical feedback to the thalamus is, in turn, the anatomically dominant input to relay cells, yet its influence on thalamic ...
Hillenbrand, Ulrich, van Hemmen, J. Leo
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Molecular Pain, 2006 Phasic and tonic inhibitions are two types of inhibitory activities involved in inhibitory processing in the CNS. In the spinal cord dorsal horn, phasic inhibition is mediated by both GABAergic and glycinergic inhibitory postsynaptic currents.
Ataka Toyofumi, Gu Jianguo G
doaj +1 more source