Results 1 to 10 of about 14,944,148 (406)
The Total Synthesis of (–)-Scabrolide A [PDF]
Journal of the American Chemical Society, 2020 The first total synthesis of the norcembranoid diterpenoid scabrolide A is disclosed. The route begins with the synthesis of two chiral pool-derived fragments, which undergo a convergent coupling to expediently introduce all 19 carbon atoms of the ...
Hafeman, Nicholas J. +5 more
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Total Synthesis and Stereochemical Assignment of Alternapyrone [PDF]
MoleculesAlternapyrone, a bioactive polyketide produced by the fungal host Aspergillus oryzae, is biosynthesized by a polyketide synthase encoded by the alt1-5 gene cluster.
Hui Zhang +5 more
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Total Synthesis of Cardenolides Acospectoside A and Acovenoside B [PDF]
MoleculesAcospectoside A (1) and acovenoside B (2), two cytotoxic cardenolides extracted from the venomous South African bush Acokanthera oppositifolia, are distinguished by their unique structural motifs of the l-acovenose moiety at C-3 and a 1β-O-acetylated ...
Benzhang Liu, Peng Xu, Biao Yu
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First total synthesis of kipukasin A [PDF]
Beilstein Journal of Organic Chemistry, 2017 In this paper, a practical approach for the total synthesis of kipukasin A is presented with 22% overall yield by using tetra-O-acetyl-β-D-ribose as starting material.
Chuang Li +4 more
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Synthetic Study toward Triterpenes from the Schisandraceae Family of Natural Products
Molecules, 2023 Triterpenoid natural products from the Schisandraceae family have long presented a significant synthetic challenge. Lancifodilactone I, a member of the family not previously synthesized, was identified as a key natural product target, from which many ...
Pavle Kravljanac, Edward A. Anderson
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Chemoenzymatic Total Synthesis of Natural Products.
Accounts of Chemical Research, 2021 ConspectusThe total synthesis of structurally complex natural products has challenged and inspired generations of chemists and remains an exciting area of active research. Despite their history as privileged bioactivity-rich scaffolds, the use of natural
Suman Chakrabarty +4 more
semanticscholar +1 more source
Progress in the total synthesis of resin glycosides
Frontiers in Chemistry, 2022 Resin glycosides, mainly distributed in plants of the family Convolvulaceae, are a class of novel and complex glycolipids. Their structural complexity and significant biological activities have received much attention from synthetic chemists, and a ...
Wenli Wang +10 more
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Recent Advances in the Stereoselective Total Synthesis of Natural Pyranones Having Long Side Chains
Molecules, 2020 Pyranone natural products have attracted great attention in recent years from chemists and biologists due to their fascinating stereoisomeric structural features and impressive bioactivities.
Satya Kumar Avula +4 more
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Optimization of Two Steps in Scale-Up Synthesis of Nannocystin A
Marine Drugs, 2021 We have accomplished a 10-step (longest linear) total synthesis of nannocystin A on a four hundred milligram scale. The previously reported Kobayashi vinylogous Mukaiyama aldol reaction to connect C4 and C5 was unreproducible during the scaling up ...
Tingrong Zhang +5 more
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ESTRATÉGIAS PARA A SÍNTESE DO ÁCIDO LISÉRGICO
Química Nova, 2021 STRATEGIES FOR THE SYNTHESIS OF LYSERGIC ACID. (+)-Lysergic acid [(+)-1] is a precursor of several substances with well-established pharmacological properties, including some drugs approved and commercialized around the world. Thus, the importance of (+)-
Tamiris R. C. Silva, Cristiano Raminelli
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