Results 41 to 50 of about 3,567,305 (338)
Synthesis of Pelorol and Its Analogs and Their Inhibitory Effects on Phosphatidylinositol 3-Kinase
Marine Drugs, 2016 There are numerous biologically active substances with novel structures and unique physiological functions in marine organisms. These substances are important sources of new lead compounds. Pelorol is a natural product isolated from marine organisms that
Yongjie Luo +3 more
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Total Synthesis of Antheliolide A [PDF]
Synfacts, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chandra Sekhar Mushti +2 more
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Synthetic Approaches to the Lamellarins—A Comprehensive Review
Marine Drugs, 2014 The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri +2 more
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Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis [PDF]
, 2008 A Phytophthora mating hormone with an array of 1,5-stereogenic centers has been synthesized by using our recently developed methodology of catalytic enantioselective conjugate addition of Grignard reagents. We applied this methodology in a diastereo- and
A. J. Minnaard +23 more
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Total Synthesis of a Marine Alkaloid—Rigidin E
Marine Drugs, 2012 In the present paper, we report an efficient total synthesis of a marine alkaloid, rigidin E. The key tetrasubstituted 2-amino-3-carboxamidepyrrole intermediate was synthesized by cascade Michael addition/intramolecular cyclization between <em>N<
Qiang Xiao +4 more
doaj +1 more source
Decision-making regarding total knee replacement surgery: a qualitative meta-synthesis [PDF]
, 2007 Knee osteoarthritis is a highly prevalent condition that can result in disability and reduced quality of life. The evidence suggests that total knee replacement surgery (TKR) is an effective intervention for patients with severe knee problems, but there ...
Jinks, C, O'Neill, T, Ong, BN
core +3 more sources
The first total synthesis of (+)-mucosin
, 2012 The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous ...
Henderson, Alan R. +3 more
core +1 more source
Molecules, 2019 The first total syntheses of izenamides A, B, and C, which are depsipeptides inhibitor of cathepsin D, were accomplished. In addition, the stereochemistry of izenamide B was confirmed by our syntheses.
Changjin Lim
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Total Synthesis of (−)‐Caprazamycin A [PDF]
Angewandte Chemie International Edition, 2015 AbstractCaprazamycin A has significant antibacterial activity against Mycobacterium tuberculosis (TB). The first total synthesis is herein reported and features a) the scalable preparation of the syn‐β‐hydroxy amino acid with a thiourea‐catalyzed diastereoselective aldol reaction, b) construction of a diazepanone with an unstable fatty‐acid side chain,
Nakamura, Hugh +5 more
openaire +5 more sources
Enantioselective Total Synthesis of (–)-Myrifabral A and B [PDF]
, 2020 A catalytic enantioselective approach to the Myrioneuron alkaloids (−)-myrifabral A and (−)-myrifabral B is described. The synthesis was enabled by a palladium-catalyzed enantioselective allylic alkylation, that generates the C(10) all-carbon quaternary ...
Bartberger, Michael D. +3 more
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