Results 71 to 80 of about 3,850,300 (360)
First total synthesis of kipukasin A
Beilstein Journal of Organic Chemistry, 2017 In this paper, a practical approach for the total synthesis of kipukasin A is presented with 22% overall yield by using tetra-O-acetyl-β-D-ribose as starting material.
Chuang Li +4 more
doaj +1 more source
Molecules, 2014 The discovery of a more cytotoxic macrosphelide derivative, including its total synthesis and bioassay are described. Application of the Koide protocol to a readily available propagylic alcohol allowed the rapid and practical synthesis of a macrosphelide
Yu Mi Heo +3 more
doaj +1 more source
Total Synthesis of (‐)‐Spongidepsin. [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Laurent, Ferrié +3 more
openaire +2 more sources
Asymmetric total synthesis of alkaloid natural products without external chiral sources [PDF]
, 2018 The chirality of a starting material having a chiral sp3-carbon can be preserved under some circumstances in the reaction product even though the reaction proceeds at the chiral carbon as a reaction center through reactive intermediates.
Kim, Sanghee
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ChemistryEuropeA concise method for the construction of dioxabicyclo[3.3.1]nonene framework has been developed. This structural motif has recently been identified in hybrid‐type pyranonaphthoquinone‐class natural products.
Yoshio Ando, Sota Ajima, Ken Ohmori
doaj +1 more source
Synthesis of the spiroketal core of integramycin
Beilstein Journal of Organic Chemistry, 2013 A concise synthetic strategy towards the spiroketal core of the HIV-integrase inhibitor integramycin (1) was developed. The required ketone precursor was efficiently constructed from two simple and easily accessible subunits by means of a ...
Evgeny. V. Prusov
doaj +1 more source
Synthetic Approaches to the Lamellarins—A Comprehensive Review
Marine Drugs, 2014 The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated ...
Dennis Imbri +2 more
doaj +1 more source
Total Synthesis of (.+‐.)‐Hasubanonine. [PDF]
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Spencer B, Jones +2 more
openaire +2 more sources
Toward the total synthesis of spirastrellolide A. Part 3: Intelligence gathering and preparation of a ring-expanded analogue [PDF]
, 2007 Different methods for the formation of the C.25–C.26 bond of spirastrellolide A (1) are evaluated that might qualify for the end game of the projected total synthesis, with emphasis on metathetic ways to forge the macrocyclic ...
Ceccon, J. +5 more
core +2 more sources