Results 71 to 80 of about 3,567,305 (338)
Total synthesis of aurofusarin: studies on the atropisomeric stability of bis-naphthoquinones [PDF]
, 2018 An efficient annulation involving pyrone addition to a quinone and Dieckmann condensation was developed for rapid assembly of a γ-naphthopyrone monomeric precursor to the bis-naphthoquinone natural product aurofusarin.
Allen +42 more
core +1 more source
Recent applications of the divinylcyclopropane–cycloheptadiene rearrangement in organic synthesis
Beilstein Journal of Organic Chemistry, 2014 This review summarizes the application of the divinylcyclopropane–cycloheptadiene rearrangement in synthetic organic chemistry. A brief overview of the new mechanistic insights concerning the title reaction is provided as well as a condensed account on ...
Sebastian Krüger, Tanja Gaich
doaj +1 more source
Synthesis of the Enantiomers of Thioridazine
SynOpen, 2020 Thioridazine, a well-known antipsychotic drug, has shown promising effects on several bacterial strains (including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus).
Simen Antonsen +7 more
doaj +1 more source
Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G
Molecules, 2021 The biological activities of shancigusin C (1) and bletistrin G (2), natural products isolated from orchids, are reported along with their first total syntheses.
Leander Geske +6 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Total synthesis of jiadifenolide. [PDF]
, 2014 As a potent neurotrophic agent, the sesquiterpenoid jiadifenolide represents a valuable small-molecule lead for the potential therapeutic treatment of neurodegenerative diseases.
Dalby, Stephen M +2 more
core +2 more sources
The total synthesis of D-chalcose and its C-3 epimer
Beilstein Journal of Organic Chemistry, 2013 We completed a new and efficient synthesis of D-chalcose (I) and the first synthesis of its C-3 epimer (I′) in nine steps with overall yields of 23% and 24%, respectively.
Jun Sun +5 more
doaj +1 more source
Total Synthesis and Metabolic Stability of Hispidulin and Its d-Labelled Derivative
Molecules, 2017 Hispidulin is a naturally occurring flavone known to have various Central nervous system (CNS) activities. Proposed synthetic approaches to synthesizing hispidulin have proven unsatisfactory due to their low feasibility and poor overall yields.
Liang-Chieh Chen +4 more
doaj +1 more source
Angewandte Chemie International Edition, 2007 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maddess, M +7 more
openaire +5 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source