Results 221 to 230 of about 5,381,284 (255)

Von In‐Silico bis In‐Cerebro – Entwicklung des Orexinrezeptor Antagonisten „Photorexant“ zur Photomodulation In Vitro und im Gehirn der Maus

open access: yesAngewandte Chemie, EarlyView.
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann   +10 more
wiley   +1 more source

Toxicological evaluation of imidazo-based heterocyclic derivatives: In-vitro and in-vivo acute toxicity studies. [PDF]

open access: yesToxicol Rep
Kumar S   +7 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

open access: yesAngewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean   +3 more
wiley   +1 more source

Safety and Toxicological Evaluation of Subunit Keyhole Limpet Hemocyanin-Loaded Lipid-PLGA Hybrid Nanoparticles (sKLH-hNPs) as a Nanocarrier for an Opioid Use Disorder Vaccine. [PDF]

open access: yesInt J Toxicol
Walter D   +11 more
europepmc   +1 more source

Toxicological Evaluation of Kaempferol and Linearolactone as Treatments for Amoebic Liver Abscess Development in Mesocricetus auratus. [PDF]

open access: yesInt J Mol Sci
Varela-Rodríguez L   +10 more
europepmc   +1 more source

Gastroprotective, Antioxidant, Anti-Inflammatory, and Toxicological Evaluation of Stem Bark Extracts of <i>Vitellaria paradoxa</i> and <i>Parkia biglobosa</i>. [PDF]

open access: yesPharmaceuticals (Basel)
Dangnon B   +10 more
europepmc   +1 more source

Toxicological evaluation of porcine bile powder in Kunming mice and Sprague-Dawley rats. [PDF]

open access: yesFront Pharmacol
Wu L   +13 more
europepmc   +1 more source

In vivo toxicological evaluation of 3-benzylideneindolin-2-one: antifungal activity against clinical isolates of dermatophytes. [PDF]

open access: yesBMC Pharmacol Toxicol
Rajakulasooriya RSR   +9 more
europepmc   +1 more source

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