Results 101 to 110 of about 1,799 (138)

Feature-based clustering of global sea level anomaly time series. [PDF]

Sci Rep
Sun Q, Wan J, Liu S.
europepmc   +1 more source

ABE9 fused to SpRY Cas9 nickase enables precise generation of bystander free mouse models. [PDF]

Sci Rep
Ong JK, Bhunia S, Hilbert B, Kirschner V, Duglosz S, Zimmermann F, Freichel M, Cornean A.   +7 more
europepmc   +1 more source

Calcium signaling in microglial immune functions: current understanding and implications for disease. [PDF]

Curr Opin Immunol
Lifton AR, DeMeulenaere KE, Prakriya M.
europepmc   +1 more source

Lysosomal Ca²⁺ Release Through TRPML1 Governs Ventricular Arrhythmia After Myocardial Infarction. [PDF]

Circ Arrhythm Electrophysiol
Xie A, Kang GJ, Liu H, Kim EJ, Feng F, Dobrev D, Dudley SC.   +6 more
europepmc   +1 more source

Targeting Endolysosomal Two-Pore Channel 2 (TPC2) as a Host-Directed Antiviral Strategy Against RNA and DNA Viruses of Global Health Concern

The rapid emergence and re-emergence of viral pathogens continues to challenge global health systems and underscores the limitations of conventional direct-acting antivirals (DAAs), which are typically virus-specific and vulnerable to resistance driven ...
Afshar Moghaddam, Houria
core  

IP3R2-mediated inter-organelle calcium signaling suppresses melanosome degradation. [PDF]

PLoS Biol
Saurav S, Jadon A, Motiani RK.
europepmc   +1 more source

Tetrandrine augments melanoma cell immunogenicity via dual inhibition of autophagic flux and proteasomal activity enhancing MHC-I presentation. [PDF]

Acta Pharmacol Sin
He LN, Liu YJ, Jiang JB, Wang DY, Li YL, Zeng SJ, Guo Z, Yao PY, Lin ZC, Lv SX, Liu XY, Guo W, Liu F, Du BY, Zhao TX, Xiao JY, Shi YF, Wang K.   +17 more
europepmc   +1 more source

Lysosomal Channels as New Molecular Targets in the Pharmacological Therapy of Neurodegenerative Diseases <i>via</i> Autophagy Regulation. [PDF]

Curr Neuropharmacol
Tedeschi V, Sapienza S, Ciancio R, Canzoniero LMT, Pannaccione A, Secondo A.   +5 more
europepmc   +1 more source

Two-pore channel regulators - Who is in control? [PDF]

Front Physiol
Deutsch R, Kudrina V, Freichel M, Grimm C.   +3 more
europepmc   +1 more source

Lysosomal Ion Channels and Transporters: Recent Findings, Therapeutic Potential, and Technical Approaches. [PDF]

Bioelectricity
Kondratskyi A, Bazzone A, Rapedius M, Zerlotti R, Masson B, Sadanandan NP, Parker JL, Santinho A, Moutia M, Thiam AR, Kemp A, Seibertz F, Murciano N, Friis S, Becker N, Obergrussberger A, Barthmes M, George C, George M, Dalrymple D, Gasnier B, Newstead S, Grimm C, Fertig N.   +23 more
europepmc   +1 more source