Results 11 to 20 of about 2,258 (177)

PANoptosis-Related Diagnostic Biomarkers in Non-Neovascular Age-Related Macular Degeneration: An Integrative Transcriptomic and Experimental Study [PDF]

Genetics Research
Age-related macular degeneration (AMD), particularly its non-neovascular (dry) form, is a progressive retinal disorder that causes central vision loss and substantial impairment in daily life.
Jiaming Li, Yirong Ma, Miao Hu, Qian Zhang, Anqi Wang, Qiuyu Tang, Qinshang Guo, Binglin Huang   +7 more
doaj   +3 more sources

Decoding the Tumor Microenvironment of Myoepithelial Cells in Triple-Negative Breast Cancer Through Single-Cell and Transcriptomic Sequencing and Establishing a Prognostic Model Based on Key Myoepithelial Cell Genes [PDF]

International Journal of Genomics
Conclusion: This study highlights MECs’ role in TNBC progression, provides a CoxBoost prognostic model for personalized treatment, and identifies TPD52 as a potential therapeutic target for TNBC intervention.
Xiaocheng Yu, Ye Tian, Rui Zhang, Yong Yang   +3 more
doaj   +3 more sources

KLF7 enhances the invasion and migration of colorectal cancer cells via the miR-139-5p/TPD52 axis [PDF]

Cancer Biology & Therapy
In this study, we aimed to investigate the molecular mechanism of Krüppel-like factor 7 (KLF7) in colorectal cancer (CRC) cell invasion and migration. The expression pattern of KLF7 in CRC tissues and the correlation between KLF7 expression and clinical ...
Juan Zhang, Zhihan Li, Jiaxu Han, Zhongtao Tian, Qingyu Meng, Wenbo Niu   +5 more
doaj   +2 more sources

Urinary proteomic profiling reveals diagnostic biomarkers and regulatory networks in myasthenia gravis [PDF]

BMC Neurology
Background Myasthenia gravis (MG) is a chronic autoimmune neuromuscular junction disorder mediated by autoantibodies. Existing diagnostic methods mainly rely on serum antibody detection and electrophysiological testing, which are limited by invasiveness ...
Jing Yang, Xi Yang, Zhen-kun Zhu, Liang Shen, Shi-ge San, Lianchen Xiao, Fan Ye, Chun-hua Wang, Kun Meng   +8 more
doaj   +2 more sources

Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells [PDF]

Biomedicines
Background/Objectives: The tumor protein D52 (TPD52) family includes TPD52, TPD53, TPD54, and TPD55. The balance between TPD52 and TPD54 expression plays an important role in high-malignant oral squamous cell carcinoma (OSCC) cells.
Masataka Watanabe, Yoshiki Mukudai, Nodoka Kindaichi, Maki Nara, Konomi Yamada, Yuzo Abe, Asami Houri, Toshikazu Shimane, Tatsuo Shirota   +8 more
doaj   +2 more sources

Hsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis

Cancer Management and Research, 2020
Peijing Shi,1 Xiaoyong Zhang,1 Chunxiang Lou,1 Yunxia Xue,1 Ruibao Guo,1 Shuzhen Chen2 1Department of Gynaecology, The Third Hospital of Ji’nan, Jinan, People’s Republic of China; 2Department of Pathology, The Third Hospital of Ji’nan ...
Shi P, Zhang X, Lou C, Xue Y, Guo R, Chen S   +5 more
doaj   +3 more sources

Unravelling the role of PRKCI and key-cancer related genes in breast cancer development and metastasis [PDF]

Discover Oncology
Background Breast cancer is one of the most common causes of fatalities in females globally. Rising cases of drug resistance against existing chemotherapeutics are great problem.
Hania Shah, Khushbukhat Khan, Yasmin Badshah, Janeen H. Trembley, Naeem Mahmood Ashraf, Maria Shabbir, Tayyaba Afsar, Dara Aldisi, Dilawer Khan, Suhail Razak   +9 more
doaj   +2 more sources

Exosomal Circ-XIAP Promotes Docetaxel Resistance in Prostate Cancer by Regulating miR-1182/TPD52 Axis

Drug Design, Development and Therapy, 2021
Hui Zhang,1 Minghui Li,1 Jing Zhang,1 Yanbing Shen,2 Qi Gui2 1College of Medical, Huanghuai University, Zhumadian, Henan, People’s Republic of China; 2Department of Urology, The Central Hospital of Zhumadian, Zhumadian, Henan, People’s ...
Zhang H, Li M, Zhang J, Shen Y, Gui Q
doaj   +4 more sources

MicroRNA binding site variants–new potential markers of primary osteoporosis in men and women [PDF]

Frontiers in Genetics
IntroductionThe identification of significant DNA markers of primary osteoporosis may gain new insights by studying genome regions involved in mechanisms of epigenetic regulation through interactions with microRNAs.MethodsThe authors searched for ...
Bulat Yalaev, Roman Deev, Anton Tyurin, Ramil Salakhov, Kirill Smirnov, Anna Eremkina, Natalia Mokrysheva, Ildar Minniakhmetov, Rita Khusainova, Rita Khusainova   +9 more
doaj   +2 more sources

Circular RNA circEZH2 Promotes Lung Adenocarcinoma Progression by Regulating microRNA-495-3p/Tumor Protein D52 Axis and Activating Nuclear Factor-Kappa B Pathway [PDF]

International Journal of General Medicine
Liping Chen,1 Tongwei Xiang,2 Jing Xing,2 Xinan Lu,2 Shan Wei,2 Huaying Wang,2 Jipeng Li,1 Wanjun Yu2 1Department of Central Laboratory, The Affiliated People’s Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of Respiratory
Chen L, Xiang T, Xing J, Lu X, Wei S, Wang H, Li J, Yu W   +7 more
doaj   +2 more sources