Decoding the Tumor Microenvironment of Myoepithelial Cells in Triple-Negative Breast Cancer Through Single-Cell and Transcriptomic Sequencing and Establishing a Prognostic Model Based on Key Myoepithelial Cell Genes [PDF]
Conclusion: This study highlights MECs’ role in TNBC progression, provides a CoxBoost prognostic model for personalized treatment, and identifies TPD52 as a potential therapeutic target for TNBC intervention.
Xiaocheng Yu +3 more
doaj +3 more sources
Hsa_circ_0007637 Facilitates Nasopharyngeal Carcinoma Progression by Sponging miR-636/TPD52 Axis
Yihong Wang,* Manyi Li,* Chen Pan,* Haiping Huang, Xiaoqing Hu, Jisheng Liu Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to this ...
Wang Y +5 more
doaj +4 more sources
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis [PDF]
Background Trichinella spiralis (T. spiralis) is a parasite occurring worldwide that has been proven to have antitumour ability. However, studies on the antitumour effects of cross antigens between the tumour and T.
Tao-Tao Yue +10 more
doaj +3 more sources
Unravelling the role of PRKCI and key-cancer related genes in breast cancer development and metastasis [PDF]
Background Breast cancer is one of the most common causes of fatalities in females globally. Rising cases of drug resistance against existing chemotherapeutics are great problem.
Hania Shah +9 more
doaj +2 more sources
Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway [PDF]
Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback.
Matteo Brindisi +5 more
doaj +4 more sources
Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer [PDF]
Background Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers.
Chenxi Zhang +6 more
doaj +2 more sources
MicroRNA binding site variants–new potential markers of primary osteoporosis in men and women [PDF]
IntroductionThe identification of significant DNA markers of primary osteoporosis may gain new insights by studying genome regions involved in mechanisms of epigenetic regulation through interactions with microRNAs.MethodsThe authors searched for ...
Bulat Yalaev +9 more
doaj +2 more sources
Circular RNA circEZH2 Promotes Lung Adenocarcinoma Progression by Regulating microRNA-495-3p/Tumor Protein D52 Axis and Activating Nuclear Factor-Kappa B Pathway [PDF]
Liping Chen,1 Tongwei Xiang,2 Jing Xing,2 Xinan Lu,2 Shan Wei,2 Huaying Wang,2 Jipeng Li,1 Wanjun Yu2 1Department of Central Laboratory, The Affiliated People’s Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of Respiratory
Chen L +7 more
doaj +2 more sources
Hsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis
Peijing Shi,1 Xiaoyong Zhang,1 Chunxiang Lou,1 Yunxia Xue,1 Ruibao Guo,1 Shuzhen Chen2 1Department of Gynaecology, The Third Hospital of Ji’nan, Jinan, People’s Republic of China; 2Department of Pathology, The Third Hospital of Ji’nan ...
Shi P +5 more
doaj +3 more sources
Overexpression of TPD52L2 in HNSCC: prognostic significance and correlation with immune infiltrates [PDF]
Background Evidence has been presented that the tumor protein D52 (TPD52) family plays a critical role in tumor development and progression. As a member of the TPD52 family, the changes in TPD52L2 gene status are instrumental in kinds of cancer ...
Min Lu +5 more
doaj +2 more sources

