Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer [PDF]
BMC Genomics, 2023 Background Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers.
Chenxi Zhang +6 more
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Overexpression of TPD52L2 in HNSCC: prognostic significance and correlation with immune infiltrates [PDF]
BMC Oral HealthBackground Evidence has been presented that the tumor protein D52 (TPD52) family plays a critical role in tumor development and progression. As a member of the TPD52 family, the changes in TPD52L2 gene status are instrumental in kinds of cancer ...
Min Lu +5 more
doaj +2 more sources
Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs [PDF]
BioData MiningObjectives Bladder cancer (BLCA) is a tumor that affects men more than women. The biological function and prognostic value of androgen-responsive genes (ARGs) in BLCA are currently unknown.
Jiang Zhao +8 more
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Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway [PDF]
Cells, 2020 Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback.
Matteo Brindisi +5 more
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TPD52 as a Therapeutic Target Identified by Machine Learning Shapes the Immune Microenvironment in Breast Cancer. [PDF]
J Cell Mol MedABSTRACT Breast cancer (BRCA) is one of the most common malignancies and a leading cause of cancer‐related mortality among women globally. Despite advances in diagnosis and treatment, the heterogeneity of BRCA presents significant challenges for effective management and prognosis.
Xia J, Zhou X.
europepmc +2 more sources
Retracted: MiR-139-5p Inhibits the Development of Gastric Cancer through Targeting TPD52. [PDF]
J Healthc Eng, 2023 Engineering JOH.
europepmc +2 more sources
MiR-139-5p Inhibits the Development of Gastric Cancer through Targeting TPD52 [PDF]
Journal of Healthcare Engineering, 2022 Background. Many researchers have confirmed that miRNAs are involved in the pathogenesis of gastric cancer (GC). This study focused on investigating the specific functions of miR-139-5p in GC. Methods. MiR-139-5p and TPD52 expressions were observed by qRT-PCR or western blot in GC.
Yuanbo Li +4 more
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Cell & Bioscience, 2021 Background Tumor protein D52 (TPD52) reportedly plays an important role in the proliferation and metastasis of various cancer cells, including oral squamous cell carcinoma (OSCC) cells, and is expressed strongly at the center of the tumor, where the ...
Yuzo Abe +8 more
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TPD52 (tumor protein D52) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on TPD52 (tumor protein D52), with data on DNA, on the protein encoded, and where the gene is implicated.
Della-Franca, A, Byrne, J
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TPD52 expression increases neutral lipid storage within cultured cells [PDF]
Journal of Cell Science, 2015 Tumor protein D52 (TPD52) is amplified/ over-expressed in cancers of diverse cellular origins. Altered cellular metabolism (including lipogenesis) is a hallmark of cancer development, and protein-protein associations between TPD52 and known regulators of lipid storage, and differential TPD52 expression in obese versus non-obese adipose tissue, suggest ...
Alvin, Kamili +11 more
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