Results 31 to 40 of about 2,290 (178)

Genome wide analysis of gene expression changes in skin from patients with type 2 diabetes [PDF]

, 2020
Non-healing chronic ulcers are a serious complication of diabetes and are a major healthcare problem. While a host of treatments have been explored to heal or prevent these ulcers from forming, these treatments have not been found to be consistently ...
A Avogaro, A Gaultier, A Le Guelte, A Magli, AA Anderson, AE Rodríguez-Fraticelli, AJ Monteforte, B Shu, BG Seligman, C Ling, C Margadant, C Ozbayer, C Shi, C Tian, C Ung, C Vanderplanck, C Wu, D Bosnakovski, D Bosnakovski, D Karthik, D Lazzaro, DJ Mangelsdorf, DM D'Souza, DS Frankel, E Ansseau, E Ansseau, E Nilsson, EA Coon, EA Malt, EM Small, F Gragnano, F Guan, G Theocharidis, G. Said, GH Wong, GJ Berry, GJ Berry, GL Bellot, GV Gnoni, H Andersen, H Brem, HA Ramirez, I Bettahi, I Bettahi, I Chakroun, I Gottfried, IN Vial, J Thimmarayappa, J Xu, J Yan, JB Rice, JC Corton, JG Van Vranken, JS Hansen, K Blackburn, KM Popov, L Nasarre, L Tan, LA Berchtold, LE Reynolds, M Gupta, M Wight, MA Faghihi, MK Montgomery, MR Tanner, MR Tanner, N Schonrock, N Takagi, NY Yoshihito Nogusa, P Hebbar, P Rajendran, PJ Batista, PM Mannucci, RB Tajhya, RC Pink, RN Weijers, RS Kaplan, RS Kiss, S Baldari, S Barrientos, S Das, S Das, S Lambert, S Rovira-Llopis, S Roy, S Sethumadhavan, SM Weis, SS Kulkarni, SV Suryavanshi, SY Park, T Fujiwara, T Khalfaoui, T Thiruvoipati, T Wang, T-H Wang, TT Hien, V Iacobazzi, V Miragliotta, VV Sinyov, W Meng, WI Sivitz, WM Longmate, WM Longmate, X Shi, X Wang, X Xie, X Yuan, X Zhao, X Zhao, Y Cai, Y Carrier, Y Chen, Y Gu, Y Konishi, Y Liu, Y Wang, Y-T Chen, Y-Y Hsieh, Z Jiang, Z-X Meng, ZKK Lawi   +120 more
core   +1 more source

TPD52 expression increases neutral lipid storage within cultured cells [PDF]

Journal of Cell Science, 2015
Tumor protein D52 (TPD52) is amplified/ over-expressed in cancers of diverse cellular origins. Altered cellular metabolism (including lipogenesis) is a hallmark of cancer development, and protein-protein associations between TPD52 and known regulators of lipid storage, and differential TPD52 expression in obese versus non-obese adipose tissue, suggest ...
Alvin, Kamili, Nuruliza, Roslan, Sarah, Frost, Laurence C, Cantrill, Dongwei, Wang, Austin, Della-Franca, Robert K, Bright, Guy E, Groblewski, Beate K, Straub, Andrew J, Hoy, Yuyan, Chen, Jennifer A, Byrne   +11 more
openaire   +2 more sources

The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) are highly expressed in colorectal cancer and correlated with poor prognosis. [PDF]

PLoS ONE, 2017
The four-transmembrane protein MAL2 and tumor protein D52 (TPD52) have been shown to be involved in tumorigenesis of various cancers. However, their roles in colorectal cancer (CRC) remain unclear.
Jingwen Li, Yongmin Li, He Liu, Yanlong Liu, Binbin Cui   +4 more
doaj   +1 more source

Determining KLF14 tertiary structure and diagnostic significance in brain cancer progression

Scientific Reports, 2022
Expression analysis of new protein targets may play a crucial role in the early detection and diagnosis of brain tumor progression. The study aimed to investigate the possible relation of KLF14, TPD52, miR-124, and PKCε in the development and progression
Kainat Zahra, Maria Shabbir, Yasmin Badshah, Janeen H. Trembley, Zunaira Badar, Khushbukhat Khan, Tayyaba Afsar, Ali Almajwal, Nawaf W. Alruwaili, Suhail Razak   +9 more
doaj   +1 more source

Tissue microarray profiling and integrative proteomics indicate the modulatory potential of Maytenus royleanus in inhibition of overexpressed TPD52 in prostate cancers

Scientific Reports, 2021
Maytenus roylanus (MEM) is a plant with anti-proliferative effects against prostate cancer. We aimed to explore the mechanism of action of MEM in prostate cancer (PCa) by employing an in vitro global proteome approach to get useful information of various
Maria Shabbir, Hasan Mukhtar, Deeba Syed, Suhail Razak, Tayyaba Afsar, Ali Almajwal, Yasmin Badshah, Dara Aldisi   +7 more
doaj   +1 more source

Genetic modifiers of cognitive maintenance among older adults. [PDF]

, 2014
ObjectiveIdentify genetic factors associated with cognitive maintenance in late life and assess their association with gray matter (GM) volume in brain networks affected in aging.MethodsWe conducted a genome-wide association study of ∼2.4 M markers to ...
Coppola, Giovanni, Evans, Daniel S, Kramer, Joel H, Tranah, Gregory J, Yaffe, Kristine, Yokoyama, Jennifer S   +5 more
core   +1 more source

Star-PAP regulates tumor protein D52 through modulating miR-449a/34a in breast cancer

Biology Open, 2019
Tumor protein D52 (TPD52) is an oncogene amplified and overexpressed in various cancers. Tumor-suppressive microRNA-449a and microRNA-34a (miR-449a/34a) were recently reported to inhibit breast cancer cell migration and invasion via targeting TPD52 ...
Aizhu Duan, Lingmei Kong, Tao An, Hongyu Zhou, Chunlei Yu, Yan Li   +5 more
doaj   +1 more source

Tumor protein D54 defines a new class of intracellular transport vesicles [PDF]

, 2019
Transport of proteins and lipids from one membrane compartment to another is via intracellular vesicles. We investigated the function of tumor protein D54 (TPD54/TPD52L2) and found that TPD54 was involved in multiple membrane trafficking pathways ...
Balch, Biesemann, Boncompain, Bonifacino, Bucci, Byrne, Byrne, Byrne, Byrne, Cao, Cheeseman, Chen, Dasari, Dunlop, Edgar, Gabrielle Larocque, Geuze, Gillingham, Gordon, Gordon, Harris, Hein, Hirst, Hou, Huang, Jimenez, Junutula, Kamili, Kitt, Klöpper, Kozik, Kulak, Li, McCaughey, Messenger, Miller, Nicholas I. Clarke, Nicholas J. Carter, Nourse, Orci, Peden, Penelope J. La-Borde, Perry, Proux-Gillardeaux, Raposo, Robinson, Schindelin, Shahheydari, Shen, Shin, Stephen J. Royle, Takamori, Thomas, Thomas, Tisdale, Vigers, Wandinger-Ness, Wilson, Wong, Wood, Xu, Yoshimura, Zhang, Zhen   +63 more
core   +1 more source

Tumor protein D52 (isoform 3) contributes to prostate cancer cell growth via targeting nuclear factor-κB transactivation in LNCaP cells

Tumor Biology, 2017
Our previous study showed that TPD52 overexpression could increase migration and proliferation of LNCaP cells contributing to the development of prostate cancer.
Chandrashekhar Dasari, Dattu Prasad Yaghnam, Reinhard Walther, Ramesh Ummanni   +3 more
doaj   +1 more source

miR-103a-3p Suppresses Cell Proliferation and Invasion by Targeting Tumor Protein D52 in Prostate Cancer

Journal of Investigative Surgery, 2021
Growing evidence points at an association between microRNAs and tumor development. Although dysregulation of microRNA-103a-3p (miR-103a-3p) in multiple human cancers has been reported, its expression in prostate cancer (PCa) remains unknown and there is ...
Jiyue Ge, Likai Mao, Weiqiang Xu, Wenge Fang, Ningning Wang, Dawen Ye, Zhuang Dong, Han Guan, Chao Guan   +8 more
doaj   +1 more source