MicroRNAs in lung cancer [PDF]
, 2017 Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this ...
An +40 more
core +1 more source
Decreased microRNA-224 and its clinical significance in non-small cell lung cancer patients [PDF]
, 2014 BACKGROUND: MicroRNA-224 has been proven dysregulated in some human malignancies and correlated with tumor progression. However, its expression and clinical significance in non–small cell lung cancer (NSCLC) is still unclear.
Dan Zhu +6 more
core +2 more sources
A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis [PDF]
Biochemical and Biophysical Research Communications, 2010 Tumor protein D52 is expressed at high levels in exocrine cells containing large secretory granules where it regulates Ca(2+)-dependent protein secretion; however, D52 expression is also highly induced in multiple cancers. The present study investigated a role for the Ca(2+)-dependent phosphorylation of D52 at the single major phospho-acceptor site ...
Diana D H, Thomas +4 more
openaire +2 more sources
Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma [PDF]
, 2017 Little is known about the function of microRNA-224 (miR-224) in medullary thyroid cancer (MTC). This study investigated the role of miR-224 expression in MTC and correlated it with mutation status in sporadic MTCs.
BAROLLO, SUSI +12 more
core +3 more sources
GLUTAMINE DEPRIVATION EFFECT ON DEK, TPD52, BRCA1, ADGRE5, LIF, GNPDA1, AND COL6A1 GENE EXPRESSIONS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2017 To study effect of glutamine deprivation on the expression of genes encoding the key proliferation associated factors on a relation to inhibition of inositol requiring enzyme-1 IRE1 in U87 glioma cells was the aim of the research.
A. P. Kharkova +6 more
doaj +1 more source
Molecular Mechanisms of Nasal Epithelium in Rhinitis and Rhinosinusitis [PDF]
, 2014 Peer ...
Fokkens, Wytske J. +7 more
core +4 more sources
Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer
Frontiers in Oncology, 2022 Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (KLF9) was also determined in order to better understand its function ...
Sadia Safi +11 more
doaj +1 more source
miR-107 enhances the sensitivity of breast cancer cells to paclitaxel
Open Medicine, 2019 Breast cancer remains the most commonly diagnosed cancer in Chinese women. Paclitaxel (PTX) is a chemotherapy medication used to treat breast cancer patients. However, a side effect of paclitaxel is the severe drug resistance.
Ma Changpo +4 more
doaj +1 more source
Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia [PDF]
The Ukrainian Biochemical Journal, 2017 We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells.
O. H. Minchenko +5 more
doaj +1 more source
Adaptive Huber Regression [PDF]
, 2018 Big data can easily be contaminated by outliers or contain variables with heavy-tailed distributions, which makes many conventional methods inadequate.
Fan, Jianqing, Sun, Qiang, Zhou, Wenxin
core +2 more sources