MicroRNAs in lung cancer [PDF]
, 2017 Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this ...
An +40 more
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Folic Acid supplementary reduce the incidence of adenocarcinoma in a mouse model of colorectal cancer: microarray gene expression profile [PDF]
, 2011 Background Whether Folic acid is a potential drug that may prevent the progression of colorectal carcinoma and when to use are important healthy issues we focus on.
Yan-Wei Lin +7 more
core +1 more source
A role for tumor protein TPD52 phosphorylation in endo-membrane trafficking during cytokinesis [PDF]
Biochemical and Biophysical Research Communications, 2010 Tumor protein D52 is expressed at high levels in exocrine cells containing large secretory granules where it regulates Ca(2+)-dependent protein secretion; however, D52 expression is also highly induced in multiple cancers. The present study investigated a role for the Ca(2+)-dependent phosphorylation of D52 at the single major phospho-acceptor site ...
Diana D H, Thomas +4 more
openaire +2 more sources
Decreased microRNA-224 and its clinical significance in non-small cell lung cancer patients [PDF]
, 2014 BACKGROUND: MicroRNA-224 has been proven dysregulated in some human malignancies and correlated with tumor progression. However, its expression and clinical significance in non–small cell lung cancer (NSCLC) is still unclear.
Dan Zhu +6 more
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BMC Cancer, 2010 Background The four-transmembrane MAL2 protein is frequently overexpressed in breast carcinoma, and MAL2 overexpression is associated with gain of the corresponding locus at chromosome 8q24.12.
Fanayan Susan +11 more
doaj +1 more source
The detection, treatment, and biology of epithelial ovarian cancer [PDF]
, 2010 Ovarian cancer is particularly insidious in nature. Its ability to go undetected until late stages coupled with its non-descript signs and symptoms make it the seventh leading cause of cancer related deaths in women.
Jennifer A.A. Gubbels +4 more
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GLUTAMINE DEPRIVATION EFFECT ON DEK, TPD52, BRCA1, ADGRE5, LIF, GNPDA1, AND COL6A1 GENE EXPRESSIONS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2017 To study effect of glutamine deprivation on the expression of genes encoding the key proliferation associated factors on a relation to inhibition of inositol requiring enzyme-1 IRE1 in U87 glioma cells was the aim of the research.
A. P. Kharkova +6 more
doaj +1 more source
Predicting 3D Structure, Cross Talks, and Prognostic Significance of KLF9 in Cervical Cancer
Frontiers in Oncology, 2022 Our study aimed to identify the new blood-based biomarkers for the diagnosis and prognosis of cervical cancer. Moreover, the three-dimensional (3D) structure of Kruppel-like factor 9 (KLF9) was also determined in order to better understand its function ...
Sadia Safi +11 more
doaj +1 more source
Prognostic Impact of miR-224 and RAS Mutations in Medullary Thyroid Carcinoma [PDF]
, 2017 Little is known about the function of microRNA-224 (miR-224) in medullary thyroid cancer (MTC). This study investigated the role of miR-224 expression in MTC and correlated it with mutation status in sporadic MTCs.
BAROLLO, SUSI +12 more
core +3 more sources
Molecular Mechanisms of Nasal Epithelium in Rhinitis and Rhinosinusitis [PDF]
, 2014 Peer ...
Fokkens, Wytske J. +7 more
core +4 more sources