Results 51 to 60 of about 2,290 (178)
Tumor protein D52 (TPD52) and cancer—oncogene understudy or understudied oncogene?
Tumor Biology, 2014 The Tumor protein D52 (TPD52) gene was identified nearly 20 years ago through its overexpression in human cancer, and a substantial body of data now strongly supports TPD52 representing a gene amplification target at chromosome 8q21.13. This review updates progress toward understanding the significance of TPD52 overexpression and targeting, both in ...
Jennifer A, Byrne +3 more
openaire +2 more sources
Endocrine Regulations, 2020 Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O. +5 more
doaj +1 more source
Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52 [PDF]
Clinical Cancer Research, 2008 Abstract Purpose: Tumor protein D52 (TPD52 or D52) is frequently overexpressed in breast and other cancers and present at increased gene copy number. It is, however, unclear whether D52 amplification and overexpression target specific functional properties of the encoded protein.
Shehata, M. +10 more
openaire +3 more sources
miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma
Frontiers in Oncology, 2022 Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun +7 more
doaj +1 more source
Randomness and preserved patterns in cancer network
, 2014 Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic ...
Jalan, Sarika +2 more
core +1 more source
Human Vaccines & Immunotherapeutics, 2022 Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo +2 more
doaj +1 more source
Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle [PDF]
, 2014 peer-reviewedBackground In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination.
Diskin, Michael G. +5 more
core +1 more source
Biomolecules & Biomedicine, 2023 Colorectal cancer (CRC) is regarded as one of the most prevalent neoplasms worldwide, and ubiquitination and N6-methyladenosine (m6A) modification regulate the outgrowth of multiple cancers.
Juncai Li +8 more
doaj +1 more source
Identification of genomic markers correlated with sensitivity in solid tumors to Dasatinib using sparse principal components [PDF]
, 2016 Background: Differential analysis techniques are commonly used to offer scientists a dimension reduction procedure and an interpretable gateway to variable selection, especially when confronting high-dimensional genomic data. Huang et al.
Ahmed Hossain +4 more
core +1 more source
MicroRNA‑103a‑3p promotes metastasis by targeting TPD52 in salivary adenoid cystic carcinoma
International Journal of Oncology, 2020 Salivary adenoid cystic carcinoma (SACC) exhibits slow continuous growth, frequent local recurrences and a high incidence of blood metastasis, with advanced lung metastasis frequently occurring and being among the primary causes of mortality. MicroRNAs (miR) serve a significant role in the initiation and development of cancer and may be tumour‑specific
Min Fu +7 more
openaire +3 more sources