Results 51 to 60 of about 2,258 (177)
miR-107 enhances the sensitivity of breast cancer cells to paclitaxel
Open Medicine, 2019 Breast cancer remains the most commonly diagnosed cancer in Chinese women. Paclitaxel (PTX) is a chemotherapy medication used to treat breast cancer patients. However, a side effect of paclitaxel is the severe drug resistance.
Ma Changpo +4 more
doaj +1 more source
Expression of tumor growth related genes in IRE1 knockdown U87 glioma cells: effect of hypoxia [PDF]
The Ukrainian Biochemical Journal, 2017 We have studied the effect of IRE1 signaling enzyme knockdown as well as hypoxia on the expression of genes encoding the important tumor growth related proteins (BRCA1, DEK, BCL2L1, COL6A1, TPD52, HOMER3, and GNPDA1) in U87 glioma cells.
O. H. Minchenko +5 more
doaj +1 more source
Tumor protein D52 (TPD52) and cancer—oncogene understudy or understudied oncogene?
Tumor Biology, 2014 The Tumor protein D52 (TPD52) gene was identified nearly 20 years ago through its overexpression in human cancer, and a substantial body of data now strongly supports TPD52 representing a gene amplification target at chromosome 8q21.13. This review updates progress toward understanding the significance of TPD52 overexpression and targeting, both in ...
Jennifer A, Byrne +3 more
openaire +2 more sources
Endocrine Regulations, 2020 Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O. +5 more
doaj +1 more source
Randomness and preserved patterns in cancer network
, 2014 Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic ...
Jalan, Sarika +2 more
core +1 more source
Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle [PDF]
, 2014 peer-reviewedBackground In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination.
Diskin, Michael G. +5 more
core +1 more source
Nonredundant Functions for Tumor Protein D52-Like Proteins Support Specific Targeting of TPD52 [PDF]
Clinical Cancer Research, 2008 Abstract Purpose: Tumor protein D52 (TPD52 or D52) is frequently overexpressed in breast and other cancers and present at increased gene copy number. It is, however, unclear whether D52 amplification and overexpression target specific functional properties of the encoded protein.
Shehata, M. +10 more
openaire +3 more sources
Adaptive Huber Regression [PDF]
, 2018 Big data can easily be contaminated by outliers or contain variables with heavy-tailed distributions, which makes many conventional methods inadequate.
Fan, Jianqing, Sun, Qiang, Zhou, Wenxin
core +2 more sources
Human Vaccines & Immunotherapeutics, 2022 Cancer immunotherapy is a powerful tool for inducing antigen-specific antitumor cytotoxic T lymphocytes (CTLs). Next-generation strategies may include vaccination against overexpressed oncogenic tumor-self antigens.
C. Riccay Elizondo +2 more
doaj +1 more source
miR-139-5p Was Identified as Biomarker of Different Molecular Subtypes of Breast Carcinoma
Frontiers in Oncology, 2022 Located on chromosome 11q13.4, miR-139-5p has been confirmed by several studies as a possible attractive biomarker for cancer, including breast cancer, but its mechanism of correlation in different molecular subtypes of breast cancer has not been ...
Haohang Sun +7 more
doaj +1 more source