Results 71 to 80 of about 2,290 (178)

TPD52L2 Is a Prognostic Biomarker and Correlated With Immune Infiltration in Lung Adenocarcinoma

Frontiers in Pharmacology, 2021
Tumor protein D52-like 2 (TPD52L2) belongs to the members of the TPD52 family. TPD52L2 was reported to regulate proliferation and apoptosis in cancer cells. However, its role in lung adenocarcinoma (LUAD) was uncertain.
Anyuan Zhong, Ting Chen, Tong Zhou, Zengli Zhang, Minhua Shi   +4 more
doaj   +1 more source

PANoptosis‐Related Diagnostic Biomarkers in Non‐Neovascular Age‐Related Macular Degeneration: An Integrative Transcriptomic and Experimental Study

Genetics Research , Volume 2026, Issue 1, 2026.
Age‐related macular degeneration (AMD), particularly its non‐neovascular (dry) form, is a progressive retinal disorder that causes central vision loss and substantial impairment in daily life. Inflammation and immune dysregulation are recognized as core drivers of AMD, yet the contribution of PANoptosis, a form of programmed cell death that integrates ...
Jiaming Li, Yirong Ma, Miao Hu, Qian Zhang, Anqi Wang, Qiuyu Tang, Qinshang Guo, Binglin Huang, Xiaoye Jin   +8 more
wiley   +1 more source

Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models

VIEW, Volume 6, Issue 5, October 2025.
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong, Ben Zhao, Shuangshuang Mao, Qingxu Liu, Yuanyuan Zhao, Yiwen Liu, Yao Luo, Qianxia Li   +7 more
wiley   +1 more source

Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow [PDF]

, 2015
Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus.
Chen, X, Cheng, Z R, Wathes, D C, Werling, D, Zhang, S   +4 more
core   +3 more sources

Analysis of the CD8+ IL-10+ T cell response elicited by vaccination with the oncogenic tumor-self protein D52

Human Vaccines & Immunotherapeutics, 2020
Development of cancer vaccines targeting tumor self-antigens is complex and challenging due to the difficulty of overcoming immune tolerance to self-proteins.
C. Riccay Elizondo, Jennifer D. Bright, Jennifer A. Byrne, Robert K. Bright   +3 more
doaj   +1 more source

Inhibiting Tumor Protein D52 function for anti-cancer therapy application [PDF]

, 2013
Tumor protein D52 (TPD52) is amplified and/or overexpressed in many cancer types. Previously, TPD52 expression has been associated with ERBB2, suggesting these oncogenes may co-operate in cancer pathogenesis.
Roslan, Nuruliza
core  

Patterns of TPD52 overexpression in multiple human solid tumor types analyzed by quantitative PCR

International Journal of Oncology, 2013
Tumor protein D52 (TPD52) is located at chromosome 8q21, a region that is frequently gained or amplified in multiple human cancer types. TPD52 has been suggested as a potential target for new anticancer therapies. In order to analyze TPD52 expression in the most prevalent human cancer types, we employed quantitative PCR to measure TPD52 mRNA levels in ...
Pierre, Tennstedt, Charlotte, Bölch, Gundula, Strobel, Sarah, Minner, Lia, Burkhardt, Tobias, Grob, Sawinee, Masser, Guido, Sauter, Thorsten, Schlomm, Ronald, Simon   +9 more
openaire   +3 more sources

SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish

Journal of Cellular Physiology, Volume 240, Issue 3, March 2025.
ABSTRACT Hematopoietic stem and progenitor cells (HSPCs) play a pivotal role in blood cell production, maintaining the health and homeostasis of individuals. Dysregulation of HSPC function can lead to blood‐related diseases, including cancer. Despite its importance, our understanding of the genes and pathways underlying HSPC development and the ...
Chang‐Kyu Oh, Man S. Kim, Unbeom Shin, Ji Wan Kang, Yun Hak Kim, Hwa Soo Ko, Jae Sun Ra, Soyul Ahn, Eun Young Choi, Sanghyeon Yu, Uijeong Nam, Taesoo Choi, Kyungjae Myung, Yoonsung Lee   +13 more
wiley   +1 more source

The imminent role of microRNAs in salivary adenoid cystic carcinoma

Translational Oncology, 2023
Unfortunately, despite the severe problem associated with salivary adenoid cystic carcinoma (SACC), it has not been studied in detail yet. Therefore, the time has come to understand the oncogenic cause of SACC and find the correct molecular markers for ...
Pawan Kumar, Ram Kumar Kumawat, Vivek Uttam, Alisha Behera, Medha Rani, Neha Singh, Tushar Singh Barwal, Uttam Sharma, Aklank Jain   +8 more
doaj   +1 more source

BCL2, IRS1, AKT3, PTEN, and HIF1A expression levels in non‐small cell lung cancer patients

Malignancy Spectrum, Volume 2, Issue 1, Page 37-45, March 2025.
Restoration of miR‐15/16, miR‐126, and miR‐128 in NSCLC might be therapeutic candidates to control cell proliferation and apoptosis. Abstract Background Lung cancer is the leading cause of cancer‐related deaths worldwide. MicroRNAs (miRNAs) are small noncoding molecules that play critical roles in cell proliferation, apoptosis, invasion, and metastasis,
Mahdi Mohammadi, Kiana Taheri, Shamim Fooladgar, Saghar Omidvar Masoumi, Elham Tafsiri   +4 more
wiley   +1 more source