Results 101 to 110 of about 4,429 (159)

GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice. [PDF]

JCI Insight
Takahashi K, Rensing NR, Eultgen EM, Williams LL, Wang SH, Nelvagal HR, Le SQ, Roberts MS, Doray B, Han EB, Dickson PI, Wong M, Sands MS, Cooper JD.   +13 more
europepmc   +1 more source

Telomerase Activity in Melanoma: Impact on Cancer Cell Proliferation Kinetics, Tumor Progression, and Clinical Therapeutic Strategies-A Scoping Review. [PDF]

Curr Oncol
Alqaisi O, Storme G, Dennis A, Dibas M, Sijarina L, Grabovci L, Al-Zghoul S, Yu E, Tai P.   +8 more
europepmc   +1 more source

Recreating pathophysiology of CLN2 disease and demonstrating reversion by TPP1 gene therapy in hiPSC-derived retinal organoids and retina-on-chip. [PDF]

Cell Rep Med
Corti S, Kim KH, Chen T, Botezatu A, Cora V, Ma K, Pashkovskaia N, Bernal Vergara A, Sperlich D, Dave K, Tolone A, Reddinger RM, Tully CB, Higgins M, Kleger A, Breunig M, Lopatta P, Wingerter S, Cipriano M, Bolz S, Ueffing M, Buss N, Loskill P, Liebau S, Achberger K.   +24 more
europepmc   +1 more source

Cryo-electron microscopy structure of the budding yeast telomerase holoenzyme. [PDF]

Science
Hu H, Neumann H, Teplitz GM, Franco-Echevarría E, Chartrand P, Wellinger RJ, Nguyen THD.   +6 more
europepmc   +1 more source

TRF1 and TRF2 form distinct shelterin subcomplexes at telomeres. [PDF]

Cell Rep
Janovič T, Perez GI, Boelting G, Schmidt JC.   +3 more
europepmc   +1 more source

Tumor Membrane Based Delivery System Encapsulating Metfornin and TPP1 Peptide for Tumor Immune Therapy. [PDF]

ACS Biomater Sci Eng
Wang X, Zhou D, Qin J, Zhang Y, Li J, Wan M, Zhu Y, Yang G.   +7 more
europepmc   +1 more source

Prognostic implications of high- OXPHOS macrophages in gastric cancer: a single-cell transcriptomics and tumor microenvironment communication study. [PDF]

Front Oncol
Lin Z, Xu Y, Xu X, Lin X, Cheng L, Zhao Q.   +5 more
europepmc   +1 more source

Benchmarking Nanopore Sequencing for CLN2 (TPP1) Mutation Detection: Integrating Rapid Genomics and Orthogonal Validation for Precision Diagnostics. [PDF]

Int J Mol Sci
Teker B, Akan G, Kazan HH, Özgen Ö, Tatonyan S, Balci MC, Karaca M, Kurekci F, Yıldız EP, Güngor O, Deniz A, Gedikbasi A, Atalar F, Gokcay GF, Poda M.   +14 more
europepmc   +1 more source

Simulation of an Asymmetric Photonic Structure Integrating Tamm Plasmon Polariton Modes and a Cavity Mode for Potential Urinary Glucose Sensing via Refractive Index Shifts. [PDF]

Biosensors (Basel)
Chou HC, Bikbaev RG, Timofeev IV, Lee MJ, Lee W.   +4 more
europepmc   +1 more source

Extracellular Vesicle-Based Urinary Proteomic Signatures Predict Remission and Relapse in Primary Membranous Nephropathy. [PDF]

Kidney Dis (Basel)
Zeng L, Sun Y, Liang T, Tang H, Ye Z, Han T, Hu Z, Peng H.   +7 more
europepmc   +1 more source