Results 31 to 40 of about 9,645,786 (257)
Expression of Trace Amine-Associated Receptors in the Grueneberg Ganglion [PDF]
Chemical Senses, 2007 The Grueneberg ganglion (GG) in the vestibule of the anterior nasal cavity is considered as an olfactory subcompartment based on expression of the olfactory marker protein (OMP) and axonal projection to the olfactory bulb. Searching for olfactory receptors present in the GG, it has been observed recently that V2r83, a member of the V2R class of ...
Joerg, Fleischer +2 more
openaire +2 more sources
Trace Amine-Associated Receptors as Emerging Therapeutic Targets [PDF]
Molecular Pharmacology, 2009 Endogenous trace amines (TAs) of unknown biological function are structurally related to classic monoaminergic neurotransmitters and found at low concentrations in the mammalian brain. Their recently discovered group of G protein-coupled receptors, trace amine-associated receptors (TAARs), may represent putative targets not only for trace and other ...
Tatyana D, Sotnikova +2 more
openaire +2 more sources
Stresses, 2022 (1) Background: Chronic psychosocial stress can lead to oral dysesthesia with tongue pain. We examined whether psychosocial stress causes orofacial pain, and analyzed the comprehensive gene expression patterns of circulating cells and transient receptor ...
Ko Ito +8 more
doaj +1 more source
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +1 more source
Trace amine receptor (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database [PDF]
, 2019 Trace amine-associated receptors were discovered from a search for novel 5-HT receptors [9], where 15 mammalian orthologues were identified and divided into two families.
Maguire, Janet J. +4 more
core +1 more source
Frontiers in Pharmacology, 2018 Individuals of many species rely on odors to communicate, find breeding partners, locate resources and sense dangers. In vertebrates, odorants are detected by chemosensory receptors of the olfactory system.
Anja Harmeier +11 more
doaj +1 more source
Trace amine-associated receptor 1 as a monoaminergic modulator in brain [PDF]
Biochemical Pharmacology, 2009 Brain monoaminergic systems play critical roles in mood, cognition, emotion, reward, learning and attention, and aberrance in brain monoaminergic activity is associated with a variety of neuropsychiatric disorders/diseases. The present commentary focuses on trace amine-associated receptor 1 (TAAR1) and its potential regulatory roles in brain ...
Zhihua, Xie, Gregory M, Miller
openaire +2 more sources
Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently
Scientific Reports, 2021 Olfactory receptor families have arisen independently several times during evolution. The origin of taar genes, one of the four major vertebrate olfactory receptor families, is disputed.
Milan Dieris +2 more
doaj +1 more source
Actions of Trace Amines in the Brain-Gut-Microbiome Axis via Trace Amine-Associated Receptor-1 (TAAR1) [PDF]
, 2020 Trace amines and their primary receptor, Trace Amine-Associated Receptor-1 (TAAR1) are widely studied for their involvement in the pathogenesis of neuropsychiatric disorders despite being found in the gastrointestinal tract at physiological levels.
González, Dulce Pamela +7 more
core +2 more sources
Incretin-like effects of small molecule trace amine-associated receptor 1 agonists
Molecular Metabolism, 2016 Objective: Type 2 diabetes and obesity are emerging pandemics in the 21st century creating worldwide urgency for the development of novel and safe therapies.
Susanne Raab +15 more
doaj +1 more source