Results 11 to 20 of about 3,486,426 (236)

Boosting transcription by transcription: enhancer-associated transcripts [PDF]

open access: yesChromosome Research, 2013
Enhancers are traditionally viewed as DNA sequences located some distance from a promoter that act in cis and in an orientation-independent fashion to increase utilization of specific promoters and thereby regulate gene expression. Much progress has been made over the last decade toward understanding how these distant elements interact with target ...
Emily M, Darrow, Brian P, Chadwick
openaire   +2 more sources

Transcriptional Activation: Tuning-up transcription [PDF]

open access: yesCurrent Biology, 1995
Eukaryotic transcription is a complex process, and recent results identify multiple steps that need to be stimulated to activate transcription, one of which is a change in conformation of the general transcription factor TFIIB.
Sheldon, Michael, Danny, Reinberg
openaire   +2 more sources

Transcription mechanisms [PDF]

open access: yesWormBook, 2006
Appropriate regulation of mRNA transcription is central to the differentiation and functions of eukaryotic cells, and to the development of complex organisms. mRNAs are synthesized by the coordinated action of a set of general transcription and mRNA modification factors.
T Keith, Blackwell, Amy K, Walker
openaire   +2 more sources

Transcription Dynamics [PDF]

open access: yesMolecular Cell, 2009
All aspects of transcription and its regulation involve dynamic events. The basal transcription machinery and regulatory components are dynamically recruited to their target genes, and dynamic interactions of transcription factors with chromatin--and with each other--play a key role in RNA polymerase assembly, initiation, and elongation.
Hager, Gordon L.   +2 more
openaire   +2 more sources

Discontinuous transcription [PDF]

open access: yesNucleus, 2018
Numerous studies based on new single-cell and single-gene techniques show that individual genes can be transcribed in short bursts or pulses accompanied by changes in pulsing frequencies. Since so many examples of such discontinuous or fluctuating transcription have been found from prokaryotes to mammals, it now seems to be a common mode of gene ...
Smirnov, Evgeny   +4 more
openaire   +2 more sources

Plant Transcription Factors @ uni-potsdam.de [PDF]

open access: yes, 2007
We present the Plant Transcription Factor Database (PlnTFDB), and the putative complete set of TFs in the algae _Chlamydomonas reinhardtii_, _Ostreococcus tauri_ and the vascular plants _Oryza sativa_ and _Arabidopsis ...
Bernd Mueller-Roeber   +3 more
core   +2 more sources

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands [PDF]

open access: yes, 1998
Sequence-specific DNA-binding small molecules that can permeate human cells potentially could regulate transcription of specific genes. Multiple cellular DNA-binding transcription factors are required by HIV type 1 for RNA synthesis.
Baird, Eldon E.   +6 more
core   +1 more source

Disembodiment: Reproduction, Transcription, And Trace [PDF]

open access: yes, 2018
This article poses the question, what is so great about the body? Recent scholarship has emphasized the concept of an embodied cognition and reminded us of the significance of embodiment in musical performance.
Aaron Einbond   +8 more
core   +1 more source

Runaway transcription [PDF]

open access: yesGenome Biology, 2013
A newly demonstrated defect in RNA polymerase II termination caused by 7SK snRNA knockdown may have revealed a novel mechanism uncoupling RNA processing from transcription.
Guo, Jiannan   +2 more
openaire   +2 more sources

Simple SVM based whole-genome segmentation [PDF]

open access: yes, 2009
We present a support vector machine (SVM) based framework for DNA segmentation into binary classes. Two applications are explored: transcription start site prediction and transcription factor binding prediction.
Adam Kowalczyk   +3 more
core   +2 more sources

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