Results 61 to 70 of about 3,372,915 (384)
Transcription and post-transcriptional regulation of spermatogenesis [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 Spermatogenesis in mammals is achieved by multiple players that pursue a common goal of generating mature spermatozoa. The developmental processes acting on male germ cells that culminate in the production of the functional spermatozoa are regulated at both the transcription and post-transcriptional levels. This review addresses recent progress towards
Anilkumar Bettegowda, Miles F. Wilkinson
openaire +3 more sources
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Stem Cell Research & Therapy, 2023 Background Human multilineage-differentiating stress enduring (Muse) cells are nontumorigenic endogenous pluripotent-like stem cells that can be easily obtained from various adult or fetal tissues.
Honorine Dushime +12 more
doaj +1 more source
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands [PDF]
, 1998 Sequence-specific DNA-binding small molecules that can permeate human cells potentially could regulate transcription of specific genes. Multiple cellular DNA-binding transcription factors are required by HIV type 1 for RNA synthesis.
Baird, Eldon E. +6 more
core +1 more source
Topic Model Robustness to Automatic Speech Recognition Errors in Podcast Transcripts [PDF]
arXiv, 2021 For a multilingual podcast streaming service, it is critical to be able to deliver relevant content to all users independent of language. Podcast content relevance is conventionally determined using various metadata sources. However, with the increasing quality of speech recognition in many languages, utilizing automatic transcriptions to provide ...
arxiv
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Improving Noise Robustness for Spoken Content Retrieval using Semi-supervised ASR and N-best Transcripts for BERT-based Ranking Models [PDF]
arXiv, 2023 BERT-based re-ranking and dense retrieval (DR) systems have been shown to improve search effectiveness for spoken content retrieval (SCR). However, both methods can still show a reduction in effectiveness when using ASR transcripts in comparison to accurate manual transcripts.
arxiv
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
iScience, 2023 Summary: Motility in Pseudomonas aeruginosa is mediated through a single, polar flagellum, which is essential for virulence, colonization, and biofilm formation.
Pankaj Kumar Sahoo, Sheenu, Deepti Jain
doaj
In Vitro Analysis of the Thyroid Hormone Receptor in Mitochondrial Transcription [PDF]
, 2017 The central dogma theory relates how DNA is transcribed into messenger RNA (mRNAs) and then translated into proteins. Since the nucleus contains the majority of the DNA in cells, research related to transcription and translation focuses on these ...
Bestwick, Megan +3 more
core +1 more source