Results 21 to 30 of about 736,695 (298)

aCPSF1 cooperates with terminator U-tract to dictate archaeal transcription termination efficacy

eLife, 2021
Recently, aCPSF1 was reported to function as the long-sought global transcription termination factor of archaea; however, the working mechanism remains elusive.
Jie Li, Lei Yue, Zhihua Li, Wenting Zhang, Bing Zhang, Fangqing Zhao, Xiuzhu Dong   +6 more
doaj   +1 more source

Identification of a Transferrable Terminator Element That Inhibits Small RNA Production and Improves Transgene Expression Levels

Frontiers in Plant Science, 2022
The role of terminators is more commonly associated with the polyadenylation and 3′ end formation of new transcripts. Recent evidence, however, suggests that this regulatory region can have a dramatic impact on gene expression.
Felipe Fenselau de Felippes, Felipe Fenselau de Felippes, Kylie Shand, Peter M. Waterhouse, Peter M. Waterhouse   +4 more
doaj   +1 more source

Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis

Bioresources and Bioprocessing, 2022
Terminators serve as the regulatory role in gene transcription termination; however, few researches about terminator optimization have been conducted, which leads to the lack of available and universal terminator for gene expression regulation in ...
Yi Rao, Jingyao Yang, Jiaqi Wang, Xinyuan Yang, Mengxi Zhang, Yangyang Zhan, Xin Ma, Dongbo Cai, Zhangqian Wang, Shouwen Chen   +9 more
doaj   +1 more source

In-depth transcriptome analysis reveals novel TARs and prevalent antisense transcription in human cell lines. [PDF]

PLoS ONE, 2010
Several recent studies have indicated that transcription is pervasive in regions outside of protein coding genes and that short antisense transcripts can originate from the promoter and terminator regions of genes.
Daniel Klevebring, Magnus Bjursell, Olof Emanuelsson, Joakim Lundeberg   +3 more
doaj   +1 more source

Balanced branching in transcription termination [PDF]

Proceedings of the National Academy of Sciences, 2001
The theory of stochastic transcription termination based on free-energy competition [von Hippel, P. H. & Yager, T. D. (1992) Science 255, 809–812 and von Hippel, P. H. & Yager, T. D. (1991) Proc. Natl. Acad. Sci.
Harrington, K. J., Laughlin, R. B., Liang, S.   +2 more
openaire   +3 more sources

The Bacillus subtilis TRAP protein can induce transcription termination in the leader region of the tryptophan biosynthetic (trp) operon independent of the trp attenuator RNA. [PDF]

PLoS ONE, 2014
In Bacillus subtilis, transcription of the tryptophan biosynthetic operon is regulated by an attenuation mechanism. When intracellular tryptophan levels are high, the TRAP protein binds to the 5' leader region of the nascent trp mRNA and induces ...
Natalie M McAdams, Paul Gollnick
doaj   +1 more source

Tail Wags Dog’s SINE: Retropositional Mechanisms of Can SINE Depend on Its A-Tail Structure

Biology, 2022
SINEs, non-autonomous short retrotransposons, are widespread in mammalian genomes. Their transcripts are generated by RNA polymerase III (pol III). Transcripts of certain SINEs can be polyadenylated, which requires polyadenylation and pol III termination
Sergei A. Kosushkin, Ilia G. Ustyantsev, Olga R. Borodulina, Nikita S. Vassetzky, Dmitri A. Kramerov   +4 more
doaj   +1 more source

Gene Architecture Facilitates Intron-Mediated Enhancement of Transcription

Frontiers in Molecular Biosciences, 2021
Introns impact several vital aspects of eukaryotic organisms like proteomic plasticity, genomic stability, stress response and gene expression. A role for introns in the regulation of gene expression at the level of transcription has been known for more ...
Katherine Dwyer, Neha Agarwal, Lori Pile, Athar Ansari   +3 more
doaj   +1 more source

Terminator-dependent facilitated recycling of RNA polymerase III provides gene-specific transcriptional activation in vivo. [PDF]

Sci Adv
Genes transcribed by the RNA polymerase (Pol) III of yeast are mostly found at sites of high transcription, genomic fragility, and replication fork stalling.
Vinayachandran V, Kumar Y, Shivaswamy S, Shukla A, Kendyala N, Pullepu D, Das K, Sanyal K, Bhargava P.   +8 more
europepmc   +2 more sources

Enhancing Transcription in Escherichia coli BW25113 and Pseudomonas Putida KT2440 Using Bacteriophage Lambda Anti-terminator Protein Q [PDF]

, 2021
Functional characterization of metagenomic DNA often involves expressing heterologous DNA into genetically tractable microorganisms such as Escherichia coli.
Khan, Jibran Amanullah
core   +1 more source