Results 31 to 40 of about 71,371 (293)
Rho-dependent terminators and transcription termination [PDF]
Microbiology, 2006 Rho-dependent transcription terminators participate in sophisticated genetic regulatory mechanisms, in both bacteria and phages; they occur in regulatory regions preceding the coding sequences of genes and within coding sequences, as well as at the end of transcriptional units, to prevent readthrough transcription.
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Regulation of Transcription Elongation and Termination [PDF]
Biomolecules, 2015 This article will review our current understanding of transcription elongation and termination in E. coli. We discuss why transcription elongation complexes pause at certain template sites and how auxiliary host and phage transcription factors affect elongation and termination.
Washburn, Robert, Gottesman, Max E.
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What Is in a Cat Scratch? Growth of Bartonella henselae in a Biofilm
Microorganisms, 2021 Bartonella henselae (B. henselae) is a gram-negative bacterium that causes cat scratch disease, bacteremia, and endocarditis, as well as other clinical presentations. B.
Udoka Okaro +2 more
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The Mechanism of Intrinsic Transcription Termination [PDF]
Molecular Cell, 1999 In bacteria, an intrinsic transcription termination signal appears in RNA as a hairpin followed by approximately eight uridines (U stretch) at the 3' terminus. This signal leads to rapid dissociation of the ternary elongation complex (TEC) into RNA, DNA, and an RNA polymerase.
Gusarov, Ivan, Nudler, Evgeny
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Plant Promoters and Terminators for High-Precision Bioengineering
BioDesign Research, 2023 High-precision bioengineering and synthetic biology require fine-tuning gene expression at both transcriptional and posttranscriptional levels. Gene transcription is tightly regulated by promoters and terminators.
Emily G. Brooks +9 more
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Topoisomerases, chromatin and transcription termination [PDF]
Transcription, 2011 In eukaryotes transcription is complicated by the DNA being packed in nucleosomes and by supercoils induced by opening of the DNA double helix during elongation. Here we discuss our recent genome-wide work regarding topoisomerases and their role in chromatin remodeling during the transcription cycle and we report a novel function for topoisomerases in ...
Mickaël, Durand-Dubief +3 more
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Nature Communications, 2020 Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remaining ...
Wooyoung Kang +6 more
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Cells, 2023 Therapy via the gene addition of the anti-sickling βAS3-globin transgene is potentially curative for all β-hemoglobinopathies and therefore of particular clinical and commercial interest.
Lola Koniali +13 more
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Orientational Control is an Efficient Control Mechanism for Phase Switching in the E coli fim System [PDF]
, 2006 The 'fim' system in 'E. coli' controls the expression of type-1 fimbriae. These are hair-like structures that can be used to attach to host cells. Fimbriation is controlled by a mechanism called ''orientational control''.
Blomfield, Ian C., Chu, Dominique
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Structural basis for transcription antitermination at bacterial intrinsic terminator
Nature Communications, 2019 Bacteriophages reprogram the host transcriptional machinery. Here the authors provide insights into the mechanism of how bacteriophages regulate host transcription by determining the cryo-EM structures of two bacterial transcription elongation complexes ...
Linlin You +8 more
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