Results 51 to 60 of about 1,124,626 (332)

The convergence of autophagy, small RNA and the stress response – implications for transgenerational epigenetic inheritance in plants

Biomolecular Concepts, 2014
Recent discoveries in eukaryotes have shown that autophagy-mediated degradation of DICER and ARGONAUTE (AGO), the proteins involved in post-transcriptional gene silencing (PTGS), can occur in response to viral infection and starvation.
Youngson Neil A., Lin Pin-Chun, Lin Shih-Shun   +2 more
doaj   +1 more source

Control of Aflatoxin Production of Aspergillus flavus and Aspergillus parasiticus Using RNA Silencing Technology by Targeting aflD (nor-1) Gene. [PDF]

, 2011
Aspergillus flavus and Aspergillus parasiticus are important pathogens of cotton, corn, peanuts and other oil-seed crops, producing toxins both in the field and during storage.
Daniel Caley, Naresh Magan, Abdel-Hadi, A, Abdel-Hadi, Ahmed, Caley, D. P., Carter, D. R., Ahmed M. Abdel-Hadi, Ahmed Abdel-Hadi, David R. F. Carter, Caley, D, Carter, D, Daniel P. Caley, Magan, Naresh, David Carter, Magan, N   +14 more
core   +1 more source

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus

Molecular Therapy: Nucleic Acids, 2014
This review discusses recent developments in the use of non-coding RNAs (ncRNAs) for the regulation of therapeutically relevant genes, with special focus on applications for the treatment of cardiovascular diseases.
Tiia Husso, Seppo Ylä-Herttuala, Mikko P Turunen   +2 more
doaj   +1 more source

The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing

Molecules and Cells, 2015
SUMMARY DNA methylation is a conserved epigenetic mark that plays important roles in plant and vertebrate development, genome stability, and gene regulation. Canonical Methyl-CpG-Binding Domain (MBD) proteins are important interpreters of DNA methylation
Zhaobo Lang, Zhaobo Lang, Mingguang Lei, Xingang Wang, K. Tang, D. Miki, Huiming Zhang, S. Mangrauthia, S. Mangrauthia, Wenshan Liu, Wenshan Liu, Wenfeng Nie, Wenfeng Nie, Guojie Ma, Jun Yan, Cheng-Guo Duan, Chuan-Chih Hsu, Chunlei Wang, W. Tao, Z. Gong, Jianhua Zhu, Jianhua Zhu   +21 more
semanticscholar   +1 more source

Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling

, 2008
In the plant pathogen Phytophthora infestans, nuclear integration of inf1 transgenic DNA sequences results in internuclear gene silencing of inf1. Although silencing is regulated at the transcriptional level, it also affects transcription from other ...
Li, S., Appiah, A.A., Shepherd, S.J., Walker, C.A., Grenville-Briggs, L., Govers, F., van West, P., West, P., van, Gow, N.A.R.   +8 more
core   +1 more source

Targeted deficiency of the transcriptional activator Hnf1 alpha alters subnuclear positioning of its genomic targets [PDF]

, 2008
DNA binding transcriptional activators play a central role in gene-selective regulation. In part, this is mediated by targeting local covalent modifications of histone tails.
Luco, Reini F., Sadoni, Nicolas, Maestro, Miguel A., Miguel A Maestro, Luco Reini F., Ferrer Jorge, Zink Daniele, Daniele Zink, Sadoni Nicolas, Nicolas Sadoni, Jorge Ferrer, Maestro Miguel A., Ferrer, Jorge, Reini F Luco, Zink, Daniele   +14 more
core   +1 more source

A high-resolution map of transcriptional repression

eLife, 2017
Turning genes on and off is essential for development and homeostasis, yet little is known about the sequence and causal role of chromatin state changes during the repression of active genes.
Ziwei Liang, Karen E Brown, Thomas Carroll, Benjamin Taylor, Isabel Ferreirós Vidal, Brian Hendrich, David Rueda, Amanda G Fisher, Matthias Merkenschlager   +8 more
doaj   +1 more source

A var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum [PDF]

, 2013
Clonally variant protein expression in the malaria parasite Plasmodium falciparum generates phenotypic variability and allows isogenic populations to adapt to environmental changes encountered during blood stage infection.
Nicolas M B Brancucci, Kathrin Witmer, Kathrin Witmer (252635), Brancucci, Nicolas M. B., Schmid, Christoph, Christoph Schmid (44586), Till S. Voss (252644), Nicolas M. B. Brancucci (579187), Till S Voss, Witmer, Kathrin, Voss, Till S., Nicolas M. B. Brancucci, Till S. Voss, Christoph Schmid   +13 more
core   +1 more source

The role of TNRC6 proteins in gene silencing [PDF]

, 2013
Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
core   +1 more source

The post-transcriptional gene silencing pathway in Eucalyptus

Genetics and Molecular Biology, 2005
Post-transcriptional gene silencing (PTGS) is a conserved surveillance mechanism that identifies and cleaves double-stranded RNA molecules and their cellular cognate transcripts.
Flávio Tetsuo Sassaki, Tiago Campos-Pereira, Ivan de Godoy Maia   +2 more
doaj   +1 more source