Results 61 to 70 of about 2,976,192 (192)

Clr4SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing of heterochromatin via Swi6 phase separation

open access: yesNature Communications
Transcriptional silencing by RNAi paradoxically relies on transcription, but how the transition from transcription to silencing is achieved has remained unclear.
Hyun-Soo Kim   +7 more
doaj   +1 more source

A var gene upstream element controls protein synthesis at the level of translation initiation in Plasmodium falciparum [PDF]

open access: yes, 2013
Clonally variant protein expression in the malaria parasite Plasmodium falciparum generates phenotypic variability and allows isogenic populations to adapt to environmental changes encountered during blood stage infection.
Nicolas M B Brancucci   +13 more
core   +1 more source

Combinatorial action of miRNAs regulates transcriptional and post-transcriptional gene silencing following in vivo PNS injury. [PDF]

open access: yesPLoS ONE, 2012
Injury response in the peripheral nervous system (PNS) is characterized by rapid alterations in the genetic program of Schwann cells. However, the epigenetic mechanisms modulating these changes remain elusive.
Tadepalli Adilakshmi   +2 more
doaj   +1 more source

The role of TNRC6 proteins in gene silencing [PDF]

open access: yes, 2013
Proteins of the GW182 family have recently emerged as key players in miRNAmediated gene silencing. They have been shown to interact with Argonaute proteins, components of the RISC and are assumed to mediate the repression in metazoa. Three paralogues are
Zipprich, Jakob Theophil
core   +1 more source

Gene Silencing: The Mechanism to Down Regulate the Target Gene

open access: yesInternational Journal of Bio-Resource and Stress Management, 2018
Gene silencing is one of the most efficient and promising functional genomics tools which down regulates the expression of a gene in a very precise manner and has significant impact on crop improvement.
Shreya   +2 more
doaj  

Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

open access: yeseLife, 2021
In animal gonads, the PIWI-interacting RNA (piRNA) pathway guards genome integrity in part through the co-transcriptional gene silencing of transposon insertions.
Evelyn L Eastwood   +8 more
doaj   +1 more source

Transcriptional Silencing of Perlecan Gene Expression by Interferon-γ [PDF]

open access: yesJournal of Biological Chemistry, 1998
Perlecan, a heparan sulfate proteoglycan of basement membranes and cell surfaces, has been implicated in the control of tumor cell growth and metastasis because of its ability to bind and store growth factors and its activity as an inducer of angiogenesis.
B, Sharma, R V, Iozzo
openaire   +2 more sources

Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]

open access: yes, 2009
Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
core   +1 more source

Functional Analysis of Cotton Leaf Curl Kokhran Virus/Cotton Leaf Curl Multan Betasatellite RNA Silencing Suppressors

open access: yesBiology, 2015
In South Asia, Cotton leaf curl disease (CLCuD) is caused by a complex of phylogenetically-related begomovirus species and a specific betasatellite, Cotton leaf curl Multan betasatellite (CLCuMuB).
Muhammad Saeed   +4 more
doaj   +1 more source

The Diversity of Plant Small RNAs Silencing Mechanisms

open access: yesCHIMIA, 2019
Small RNAs gene regulation was first discovered about 20 years ago. It represents a conserve gene regulation mechanism across eukaryotes and is associated to key regulatory processes.
Jens A. Schröder, Pauline E. Jullien
doaj   +1 more source

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