Enhancement of post-transcriptional gene silencing by grafting [PDF]
Plant Signaling & Behavior, 2008 We showed previously that grafting transmitted silencing occurred when transgenic ACC oxidase 1 (ACO1) overexpressing tomato plants that also produced siRNAs were grafted onto transgenic stocks that already showed strong silencing. The presence of siRNAs in these overexpressing scions may indicate that silencing, though inefficient, may already occur ...
Yuanhuai, Han, Donald, Grierson
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The SCFDia2 ubiquitin E3 ligase ubiquitylates Sir4 and functions in transcriptional silencing. [PDF]
PLoS Genetics, 2012 In budding yeast, transcriptional silencing, which is important to regulate gene expression and maintain genome integrity, requires silent information regulator (Sir) proteins.
Rebecca J Burgess +4 more
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Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing. [PDF]
Genes Dev, 2016 In eukaryotes, antisense transcription can regulate sense transcription by induction of epigenetic modifications. We showed previously that antisense transcription triggers Dicer-independent siRNA (disiRNA) production and disiRNA locus DNA methylation (DLDM) in Neurospora crassa.
Dang Y, Cheng J, Sun X, Zhou Z, Liu Y.
europepmc +4 more sources
A Method to Produce vsiRNAs in Plants with Cross-Kingdom Gene Silencing Capacity
Applied Sciences, 2022 Plants have evolved defense mechanisms to suppress viral transcription and replication by transcriptional and post-transcriptional gene silencing mediated by virus-derived small interfering RNAs (vsiRNAs).
Hernán de Jesús Villanueva-Alonzo +11 more
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PLoS ONE, 2013 BackgroundBeyond their role in post-transcriptional gene silencing, Dicer and Argonaute, two components of the RNA interference (RNAi) machinery, were shown to be involved in epigenetic regulation of centromeric heterochromatin and transcriptional gene ...
Filippo M Cernilogar +5 more
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RNA-Mediated Gene Silencing Signals Are Not Graft Transmissible from the Rootstock to the Scion in Greenhouse-Grown Apple Plants Malus sp. [PDF]
, 2012 RNA silencing describes the sequence specific degradation of RNA targets. Silencing is a non-cell autonomous event that is graft transmissible in different plant species.
Hanke, Magda-Viola +14 more
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RNA duplexes in transcriptional regulation
Biomolecular Concepts, 2010 Transcriptional regulation by small RNA molecules, including small interfering RNA and microRNA, has emerged as an important gene expression modulator.
Swaminathan Sanjay +3 more
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eIF4GI facilitates the MicroRNA-mediated gene silencing. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional gene silencing by binding to complementary target mRNAs and recruiting the miRNA-containing ribonucleoprotein complexes to the mRNAs.
Incheol Ryu +4 more
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Splayed : a chromatin remodeler regulating tissue specific gene silencing and developmental timing [PDF]
, 2014 A number of mechanisms that contribute to epigenetic regulation of gene expression have been described in plants. The concert actions of these mechanisms contribute to proper patterning of gene expression within organs and tissues, therefore insuring ...
Fal, Kateryna
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Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing [PDF]
Molecular Cell, 2009 Heterochromatin assembly in budding yeast requires the SIR complex, which contains the NAD-dependent deacetylase Sir2 and the Sir3 and Sir4 proteins. Sir3 binds to nucleosomes containing deacetylated histone H4 lysine 16 (H4K16) and, with Sir4, promotes spreading of Sir2 and deacetylation along the chromatin fiber.
Johnson, Aaron +5 more
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