Results 21 to 30 of about 242,580 (255)
Enhancement of post-transcriptional gene silencing by grafting [PDF]
Plant Signaling & Behavior, 2008 We showed previously that grafting transmitted silencing occurred when transgenic ACC oxidase 1 (ACO1) overexpressing tomato plants that also produced siRNAs were grafted onto transgenic stocks that already showed strong silencing. The presence of siRNAs in these overexpressing scions may indicate that silencing, though inefficient, may already occur ...
Yuanhuai, Han, Donald, Grierson
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Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing [PDF]
Molecular Cell, 2009 Heterochromatin assembly in budding yeast requires the SIR complex, which contains the NAD-dependent deacetylase Sir2 and the Sir3 and Sir4 proteins. Sir3 binds to nucleosomes containing deacetylated histone H4 lysine 16 (H4K16) and, with Sir4, promotes spreading of Sir2 and deacetylation along the chromatin fiber.
Johnson, Aaron +5 more
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The SCFDia2 ubiquitin E3 ligase ubiquitylates Sir4 and functions in transcriptional silencing. [PDF]
PLoS Genetics, 2012 In budding yeast, transcriptional silencing, which is important to regulate gene expression and maintain genome integrity, requires silent information regulator (Sir) proteins.
Rebecca J Burgess +4 more
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A Method to Produce vsiRNAs in Plants with Cross-Kingdom Gene Silencing Capacity
Applied Sciences, 2022 Plants have evolved defense mechanisms to suppress viral transcription and replication by transcriptional and post-transcriptional gene silencing mediated by virus-derived small interfering RNAs (vsiRNAs).
Hernán de Jesús Villanueva-Alonzo +11 more
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PLoS ONE, 2013 BackgroundBeyond their role in post-transcriptional gene silencing, Dicer and Argonaute, two components of the RNA interference (RNAi) machinery, were shown to be involved in epigenetic regulation of centromeric heterochromatin and transcriptional gene ...
Filippo M Cernilogar +5 more
doaj +1 more source
eIF4GI facilitates the MicroRNA-mediated gene silencing. [PDF]
PLoS ONE, 2013 MicroRNAs (miRNAs) are small noncoding RNAs that mediate post-transcriptional gene silencing by binding to complementary target mRNAs and recruiting the miRNA-containing ribonucleoprotein complexes to the mRNAs.
Incheol Ryu +4 more
doaj +1 more source
RNA duplexes in transcriptional regulation
Biomolecular Concepts, 2010 Transcriptional regulation by small RNA molecules, including small interfering RNA and microRNA, has emerged as an important gene expression modulator.
Swaminathan Sanjay +3 more
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In vivo expression of MHC class I genes depends on the presence of a downstream barrier element. [PDF]
PLoS ONE, 2009 Regulation of MHC class I gene expression is critical to achieve proper immune surveillance. In this work, we identify elements downstream of the MHC class I promoter that are necessary for appropriate in vivo regulation: a novel barrier element that ...
Helit Cohen +5 more
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Biomolecular Concepts, 2014 Recent discoveries in eukaryotes have shown that autophagy-mediated degradation of DICER and ARGONAUTE (AGO), the proteins involved in post-transcriptional gene silencing (PTGS), can occur in response to viral infection and starvation.
Youngson Neil A. +2 more
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Transcriptional Gene Silencing (TGS) via the RNAi Machinery in HIV-1 Infections
Biology, 2012 Gene silencing via non-coding RNA, such as siRNA and miRNA, can occur at the transcriptional, post-transcriptional, and translational stages of expression.
Fatah Kashanchi +7 more
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