Results 21 to 30 of about 357,564 (302)

The Whys and Wherefores of Transitivity in Plants

open access: yesFrontiers in Plant Science, 2020
Transitivity in plants is a mechanism that produces secondary small interfering RNAs (siRNAs) from a transcript targeted by primary small RNAs (sRNAs). It expands the silencing signal to additional sequences of the transcript.
Felipe F. de Felippes   +1 more
doaj   +1 more source

The SCFDia2 ubiquitin E3 ligase ubiquitylates Sir4 and functions in transcriptional silencing. [PDF]

open access: yesPLoS Genetics, 2012
In budding yeast, transcriptional silencing, which is important to regulate gene expression and maintain genome integrity, requires silent information regulator (Sir) proteins.
Rebecca J Burgess   +4 more
doaj   +1 more source

Enhancement of Recombinant Protein Production in Transgenic Nicotiana benthamiana Plant Cell Suspension Cultures with Co-Cultivation of Agrobacterium Containing Silencing Suppressors. [PDF]

open access: yes, 2018
We have previously demonstrated that the inducible plant viral vector (CMViva) in transgenic plant cell cultures can significantly improve the productivity of extracellular functional recombinant human alpha-1-antiryspin (rAAT) compared with either a ...
Dandekar, Abhaya M   +3 more
core   +3 more sources

Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing [PDF]

open access: yesMolecular Cell, 2009
Heterochromatin assembly in budding yeast requires the SIR complex, which contains the NAD-dependent deacetylase Sir2 and the Sir3 and Sir4 proteins. Sir3 binds to nucleosomes containing deacetylated histone H4 lysine 16 (H4K16) and, with Sir4, promotes spreading of Sir2 and deacetylation along the chromatin fiber.
Johnson, Aaron   +5 more
openaire   +2 more sources

RNA-Mediated Gene Silencing Signals Are Not Graft Transmissible from the Rootstock to the Scion in Greenhouse-Grown Apple Plants Malus sp. [PDF]

open access: yes, 2012
RNA silencing describes the sequence specific degradation of RNA targets. Silencing is a non-cell autonomous event that is graft transmissible in different plant species.
Bai   +37 more
core   +3 more sources

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context [PDF]

open access: yes, 2018
Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling ...
Abdel-Rahman, Mohamed H.   +736 more
core   +3 more sources

Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]

open access: yes, 2016
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
A Ellahi   +56 more
core   +1 more source

A Method to Produce vsiRNAs in Plants with Cross-Kingdom Gene Silencing Capacity

open access: yesApplied Sciences, 2022
Plants have evolved defense mechanisms to suppress viral transcription and replication by transcriptional and post-transcriptional gene silencing mediated by virus-derived small interfering RNAs (vsiRNAs).
Hernán de Jesús Villanueva-Alonzo   +11 more
doaj   +1 more source

Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]

open access: yes, 2013
RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif   +2 more
core   +3 more sources

Endogenous Targets of Transcriptional Gene Silencing in Arabidopsis [PDF]

open access: yesThe Plant Cell, 2000
Transcriptional gene silencing (TGS) frequently inactivates foreign genes integrated into plant genomes but very likely also suppresses an unknown subset of chromosomal information. Accordingly, RNA analysis of mutants impaired in silencing should uncover endogenous targets of this epigenetic regulation.
Steimer, A.   +5 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy