Results 61 to 70 of about 40,064,733 (237)
Genetic insights into the dissolution of dioecy in diploid persimmon Diospyros oleifera Cheng
BMC Plant Biology, 2023 Background Dioecy, a sexual system of single-sexual (gynoecious/androecious) individuals, is rare in flowering plants. This rarity may be a result of the frequent transition from dioecy into systems with co-sexual individuals.Peng Sun, Soichiro Nishiyama, Huawei Li, Yini Mai, Weijuan Han, Yujing Suo, Chengzhi Liang, Huilong Du, Songfeng Diao, Yiru Wang, Jiaying Yuan, Yue Zhang, Ryutaro Tao, Fangdong Li, Jianmin Fu +14 moredoaj +1 more sourceSpatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours +11 morewiley +1 more sourceGenome-wide association study of behavioural and psychiatric features in human prion disease. [PDF]
, 2015 Prion diseases are rare neurodegenerative conditions causing highly variable clinical syndromes, which often include prominent neuropsychiatric symptoms.Carswell, C, MacKay, A, Thompson, AG, Porter, MC, Rudge, P, Collinge, J, Lowe, J, Mead, S, Uphill, J, Lukic, A +9 morecore A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis [PDF]
, 2009 The cause of sporadic amyotrophic lateral sclerosis (ALS) is largely unknown, but genetic factors are thought to play a significant role in determining susceptibility to motor neuron degeneration.Sendtner, M., Ding, J., Guralnik, J., Sabatelli, M., Dunkley, T., Marinou, K., F. Valentino, Singleton, A, LA BELLA V, Shiao-Lin Lai, Zachary Simmons, D. J. Hunter, LA BELLA, Vincenzo, MANCARDI GL, Hardy, J., Bandinelli, S, Fisher, E.M., Wichmann, H.-E., Beck, M, SCHMIDT S, Carlesi, C, ORRELL RW, Lupoli ,S, CAPONNETTO C, Federica Lombardo, Kwee, L. C., SICILIANO, GABRIELE, Bandinelli ,S, Mancardi, GL, D. Hernandez, Arepalli ,S, Connor ,J, I. Rafferty, Kwee ,LC, Schymick, JC, Chanock ,SJ, Siciliano, G., Conte, Amelia, Bandinelli, S., F. Torri, Gieger, C, MANCARDI, GIOVANNI LUIGI, SCHYMICK J, J. Ding, Singleton ,A, Sabatelli ,M, Dunkley ,T, KASPERAVICIUTE D, Hunter ,DJ, Simmons ,Z, Lupoli, S., Schmidt ,S, Beck ,M, Giannini, F., Rothstein ,J, Carlesi, C., Pioro, EP, CHANOCK SJ, PIORO E, Oddone, E.Z., Macciardi, F., S. Arepalli, VALENTINO F, Lai, S.-L., B. J. Traynor, Sara Lupoli, Mandrioli, J, Stefania Battistini, Schymick, J. C., STEPHAN D, FUNG H, Kasperaviciute, D., Gibbs, J.R., Mancardi ,GL, CARLESI, CECILIA, M. Sendtner, H. Fung, Arepalli, S, Guralnik, J, Mandrioli ,J, Battistini ,S, Lupoli, S, MORA G, KWEE L, Mario Sabatelli, KWEE LC, Ilaria Bartolomei, Schymick,JC, Hardy ,J, Sendtner, M, Adriano Chiò, Sola, P, Dena Hernandez, LAI S, Kwee, LC, Ding, J.H., Battistini, S., Wichmann, H. E., Crews ,C, MUTANI R, Salvi, F, Simmons, Z, J. Mandrioli, Carlesi ,C, Calvo, A., SABATELLI M, Sampath Arepalli, BATTISTINI S, Rothstein, J, NALLS M, A. Calvo, Salvi ,F, Scholz, S. W., Jabonka ,S, ODDONE E, FISHER E, TRAYNOR BJ, CHIO' A, Sola ,P, Chanock, S.J., K. Marinou, Valentino, F, Britton, A, Travis Dunkley, Andrew Singleton, Fisher, E. M., Ferrucci, L, Hunter, DJ, C. Crews, Gibbs, JR, F. Salvi, CONTE A, HARDY J, Mancardi, G.L., Dunkley, T, FUNG HC, L. Ferrucci, Dalia Kasperaviciute, Luigi Ferrucci, Lucie Bruijn, BERGER S, Beck, M., Scholz,SW, Fisher, EM, Sola, P., TORRI F, Lombardo, F, BARTOLOMEI I, Nalls, M, Restagno,G, Sonja W. Scholz, Amelia Conte, S. Bandinelli, Salvi, F., Restagno, G, Thomas ,G, Conte, A., Sendtner ,M, Z. Simmons, SENDTNER M, Mora, G, Macciardi, F, C. Caponnetto, Michael Nalls, Tedeschi ,G, G. Restagno, TRAYNOR B., LOMBARDO F, Scholz, S.W., Crews, C, L. Bruijn, Lai ,SL, Ding ,J, James Connor, Mutani, R., Caponnetto, C., Wichmann ,HE, E. P. Pioro, Hernandez ,D, H. E. Wichmann, Ferrucci ,L, Monsurro, M.R., Britton ,A, SICILIANO G, A. Conte, Jabonka, S, Tedeschi, G, Stephan, D.A., John Hardy, Rafferty, I., DING J, Gabriele Mora, CHIÒ A, P. Sola, Erik P. Pioro, Chanock, SJ, Kalliopi Marinou, Stephen J. Chanock, Mora ,G, Stephan, D. A., TEDESCHI G, Chio, A., Connor, J, Sibylle Jabonka, Traynor, B.J., Nalls ,M, David J. Hunter, Gibbs ,JR, BECK M, MONSURRO', Maria Rosaria, Bruijn, L., S. Berger, Pioro, E.P., H. C. Fung, FERRUCCI L, RESTAGNO G, LAI SL, Hernandez, D, F. Lombardo, J. Hardy, Jeffrey Rothstein, Ding, J, J. C. Schymick, Restagno, G., Valentino, F., Stefania Bandinelli, Gieger ,C, Lai, SL, Giovanni Luigi Mancardi, Rafferty, I, R. Mutani, C. Gieger, HUNTER D, Eugene Z. Oddone, Oddone, E. Z., Maria Rosaria Monsurrò, Ferrucci, L., D. Kasperaviciute, Vincenzo La Bella, ORRELL R, S. Battistini, G. Tedeschi, Fung, HC, Pioro, E. P., ROTHSTEIN J, CHANOCK S, Connor, J., Thomas, G., Arepalli, S., A. Chiò, Oddone, EZ, TEDESCHI, Gioacchino, Bryan J. Traynor, S. Lai, Kwee, L.C., Mutani, R, La Bella, V., TALBOT K, A. Britton, Hunter, D.J., Orrell, R.W., Sabatelli, Mario, J. Guralnik, Bartolomei ,I, M. R. Monsurrò, Gioacchino Tedeschi, Gibbs, J. R., D. A. Stephan, Stephen Berger, SIMMONS Z, Torri, F, Singleton, A., Claudia Caponnetto, Rafferty ,I, GuralMnik ,J, GIBBS JR, CAPONETTO C, Cecilia Carlesi, RAFFERTY I, Schymick, J.C., E. Z. Oddone, Roberto Mutani, N. Washecka, Traynor, B. J., Traynor,BJ, Tedeschi, G., J. R. Gibbs, Marinou, K, Chiò, A, Fabio Giannini, Kasperaviciute ,D, GIEGER C, MARINOU K, Michael Sendtner, BRITTON A, DUNKLEY T, Dietrich A. Stephan, Gieger, C., Mancardi, G. L., S. L. Lai, Rothstein, J., CREWS C, Talbot, K., Simmons, Z., M. Sabatelli, JABONKA S, I. Bartolomei, Cynthia Crews, Hernandez, D., Berger ,S, BANDINELI S, Mora, G., Crews, C., G. L. Mancardi, Washecka ,N, WICHMANN H, Gabriella Restagno, Stephan, DA, La Bella, V, PIORO EP, FISHER EM, Wichmann, HE, H. Erich Wichmann, Lombardo ,F, Macciardi ,F, Lai, S.L., CALVO A, V. La Bella, V. L. Bella, Fung ,HC, Jinhui Ding, Kasperaviciute, D, Fisher ,EM, SCHYMICK JC, SOLA P, Bartolomei, I., Lydia Coulter Kwee, J. Raphael Gibbs, GURALNIK J, Thomas, G, Nicole Washecka, Fung, H.-C., Jessica Mandrioli, BATTISTINI, STEFANIA, M. Beck, Orrell, R. W., T. Dunkley, Hon-Chung Fung, D. Hunter, CONNOR J, Jack Guralnik, Mandrioli, J., J. Connor, Jennifer C. Schymick, R. W. Orrell, SINGLETON A, Schmidt, S., Schmidt, S, Conte, A, S. Jabonka, Elizabeth M. Fisher, Hardy, J, Angela Britton, Lombardo, F., Talbot, K, Kevin Talbot, Bruijn ,L, Giannini ,F, A. Singleton, Chanock, S. J., Stephan ,DA, Calvo, A, Pioro ,EP, SALVI F, Battistini, S, Berger, S, WICHMANN HE, MANDRIOLI J, Nalls, M., Scholz, SW, Federica Torri, SCHOLZ SW, Sabatelli, M, Traynor, BJ, Fabrizio Salvi, Jabonka, S., Berger, S., G. Siciliano, MANCARDI G, Calvo ,A, Bruijn, L, Orrell ,RW, Marcus Beck, MACCIARDI F, K. Talbot, HUNTER DJ, Siciliano, G, Washecka, N, G. Mora, Mutani ,R, Fabio Macciardi, S. J. Chanock, C. Carlesi, SCHOLZ S, Conte ,A, S. W. Scholz, Christian Gieger, Caponnetto, C, VALENTINO, Francesca, Siciliano ,G, Bartolomei, I, Talbot ,K, HERNANDEZ D, E. M. Fisher, GIANNINI, FABIO, WASHECKA N, STEPHAN DA, S. Lupoli, BRUIJN L, F. Giannini, Gabriele Siciliano, Monsurrò ,MR, Fung, H.C., Richard W. Orrell, Silke Schmidt, Oddone ,EZ, Orrell, RW, AREPALLI S, L. C. Kwee, Gilles Thomas, Torri, F., M. Nalls, Ian Rafferty, ODDONE EZ, CARLESI C, Francesca Valentino, Marinou ,K, Giannini, F, Hunter, D. J., GIANNINI F, J. Rothstein, THOMAS J, G. Thomas, THOMAS G, BANDINELLI S, Andrea Calvo, Patrizia Sola, LUPOLI S, Washecka, N., Chiò,A, Caponnetto ,C, GIBBS J, Torri ,F, Britton, A., F. Macciardi, S. Schmidt, Monsurrò, MR, Monsurro, M. R., MONSURRÒ MR, Mutani, Roberto, Calvo, Andrea, Chio', Adriano +461 morecore +2 more sourcesCEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth +3 morewiley +1 more sourceGenome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importnace of Lp(a) [PDF]
, 2012 We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the ...Postmus, Iris, Colhoun, H.M., McKeigue, Paul M, Stanton, A.V., Trompet, S., Hyde, Craig, Colhoun, Helen M, Caulfield, M., Shields, Denis C., Hitman, Graham A, CARDS, Poulter, Neil, Shields, D.C., Sever, P., Chatterjee, Aurobindo, Trompet, Stella, Durrington, Paul N, Deshmukh, H.A., DeMicco, D.A., Calle, Roberto A., Hitman, Graham A., Neil, A., McKeigue, Paul M., Fuller, John H., Postmus, I., Hitman, G.A., DeMicco, David A., Johnson, T., ?, ?, Calle, Roberto A, Betteridge, D.J., Livingstone, Shona, Ford, Ian, McKeigue, P.M., Stanton, Alice V., Jukema, J.W., Johnson, Toby, Durrington, Paul N., Neil, Andrew, PROSPER Investigators, Livingstone, S., Jukema, J. Wouter, ASCOT, Colhoun, Helen, Ford, I., Sever, Peter, Fuller, J.H., Jukema, J Wouter, Caulfield, Mark, Fuller, John H, Chatterjee, A., Deshmukh, Harshal A, Calle, R.A., Hyde, C., Charlton-Menys, V., Poulter, N., Charlton-Menys, Valentine, DeMicco, David A, Betteridge, D John, McKeigue, Paul M.; id_orcid, Betteridge, D. John, Durrington, P.N., Colhoun, Helen M., Shields, Denis C, Deshmukh, Harshal A., Stanton, Alice V +65 morecore +1 more source