Results 41 to 50 of about 399,869 (302)

Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts

Cardiology Journal, 2020
BACKGROUND: Cardiac fibroblasts (CFs) are principal extracellular matrix-producing cells. In response to injury, CFs transdifferentiate into myofibroblasts. Intracellular calcium (Ca2+) signaling, involved in fibroblast proliferation and differentiation,
Min-Soo Ahn, Young Woo Eom, Ji-Eun Oh, Seung-Kuy Cha, Kyu Sang Park, Jung-Woo Son, Jun-Won Lee, Young Jin Youn, Sung Gyun Ahn, Jang-Young Kim, Seung-Hwan Lee, Junghan Yoon, Byung-Su Yoo   +12 more
doaj   +1 more source

Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling [Corrigendum]

Drug Design, Development and Therapy, 2020
Yu J, Zhu C, Yin J, et al. Drug Des Dev Ther. 2020;14:361–370.The authors have advised that in Figure 3 on page 365, the image of the Blank group was mistakenly duplicated from the NC group.Read the original ...
Yu J, Zhu C, Yin J, Yu D, Wan F, Tang X, Jiang X   +6 more
doaj  

Analyses of Synthetic N‑Acyl Dopamine Derivatives Revealing Different Structural Requirements for Their Anti-inflammatory and Transient-Receptor-Potential-Channel-of-the-Vanilloid-Receptor-Subfamily-Subtype‑1 (TRPV1)-Activating Properties

, 2018
We studied the chemical entities within N-octanoyl dopamine (NOD) responsible for the activation of transient-receptor-potential channels of the vanilloid-receptor subtype 1 (TRPV1) and inhibition of inflammation.
Bastian Theisinger (310806), Björn B. Hofmann (5044262), Ralf Loesel (452852), Wolfgang Greffrath (310805), Björn Wängler (1801330), Eleni Stamellou (452849), Martin C. Harmsen (4389586), Handan Moerz (5044259), Marc Pretze (3131406), Julio Caballero (531146), Bernhard K. Krämer (5044253), Yingchun Li (636496), Rolf-Detlef Treede (226189), Anna-Isabelle Kälsch (5044256), Carmen Wängler (1790250), Mathias Hafner (144687), Benito A. Yard (310816), Sarah Klotz (290590), Uta Binzen (310804), Steffen Roth (496337), Prama Pallavi (577866)   +20 more
core   +1 more source

Function and therapeutic potential of transient receptor potential ankyrin 1 in fibrosis

Frontiers in Pharmacology, 2022
The transient receptor potential (TRP) protein superfamily is a special group of cation channels expressed in different cell types and signaling pathways.
Yicheng Wei, Yicheng Wei, Yicheng Wei, Jialuo Cai, Jialuo Cai, Ruiqiu Zhu, Ruiqiu Zhu, Ke Xu, Ke Xu, Hongchang Li, Jianxin Li   +10 more
doaj   +1 more source

Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy

, 2018
Cellular transport of ions, especially by ion channels, regulates physiological function. The transient receptor potential (TRP) channels, with 30 identified so far, are cation channels with high calcium permeability.
Bishnoi, M., Panchal, SK, Khare, P., Panchal, Sunil K. (R20071), Khare, Pragyanshu, L. Brown, Panchal, S. K., Brown, Lindsay, M. Bishnoi, P. Khare, Bishnoi, M, S. K. Panchal, Brown, L., Khare, P, Bishnoi, Mahendra, Brown, L   +15 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

TRPM1 (transient receptor potential cation channel, subfamily M, member 1) [PDF]

, 2010
Review on TRPM1 (transient receptor potential cation channel, subfamily M, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Setaluri, V, S Devi, V Setaluri, Devi, S
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

MAMMALIAN TRANSIENT RECEPTOR POTENTIAL TRPA1 CHANNELS: FROM STRUCTURE TO DISEASE

, 2019
The transient receptor potential ankyrin (TRPA) channels are Ca2+-permeable nonselective cation channels remarkably conserved through the animal kingdom.
Boonen, Brett, Brett Boonen, Yeranddy A. Alpizar, Startek, Justyna B., Alvarez-Collazo, Julio, Alpizar, Yeranddy A., Julio Alvarez-Collazo, Talavera, Karel, Bernd Nilius, Naert, Robbe, Alicia Sanchez, Karel Talavera, Nilius, Bernd, AGUIAR ALPIZAR, Yeranddy, Robbe Naert, Alpizar, Yeranddy A, Justyna B. Startek, Startek, Justyna B, Sanchez, Alicia   +18 more
core   +1 more source

TRPV1 (transient receptor potential cation channel, subfamily V, member 1) [PDF]

, 2010
Review on TRPV1 (transient receptor potential cation channel, subfamily V, member 1), with data on DNA, on the protein encoded, and where the gene is ...
Santoni, G, Nabissi, M, NABISSI, MASSIMO, SANTONI, Giorgio   +3 more
core   +1 more source