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Transient Receptor Potential Cation Channels in Disease [PDF]
Physiological Reviews, 2007 The transient receptor potential (TRP) superfamily consists of a large number of cation channels that are mostly permeable to both monovalent and divalent cations. The 28 mammalian TRP channels can be subdivided into six main subfamilies: the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystin), TRPML (mucolipin), and the TRPA ...
Nilius, Bernd +3 more
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Taiwan Journal of Ophthalmology, 2020 PURPOSE: We determined if the immunohistochemical expression pattern of transient receptor potential vanilloid (TRPV) family members and TRP ankyrin 1 (TRPA1) differs among a healthy conjunctival epithelium and diseased epithelia.
Ai Izutani-Kitano +4 more
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Transient receptor potential Ankyrin 1: structure, function and ligands [PDF]
Research Results in Pharmacology, 2022 Introduction: Transient receptor potential ankyrin 1 (TRPA1) is a protein expressed in many living organisms. During the study of TRPA1, its unique biological role as a universal and polymodal sensor of various altering agents was found.
Natalia V. Pyatigorskaya +3 more
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A novel ion channel formed by interaction of TRPML3 with TRPV5. [PDF]
, 2013 TRPML3 and TRPV5 are members of the mucolipin (TRPML) and TRPV subfamilies of transient receptor potential (TRP) cation channels. Based on sequence similarities of the pore forming regions and on structure-function evidence, we hypothesized that the pore
Becker, Lars +14 more
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Transient Receptor Potential (TRP) Channels [PDF]
, 2018 Transient Receptor Potential (TRP) channels are evolutionarily conserved integral membrane proteins. The mammalian TRP superfamily of ion channels consists of 28 cation permeable channels that are grouped into six subfamilies based on sequence homology (Fig. 6.1).
Amrita, Samanta +2 more
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Remedia Sternutatoria over the Centuries: TRP Mediation
Molecules, 2021 Sneezing (sternutatio) is a poorly understood polysynaptic physiologic reflex phenomenon. Sneezing has exerted a strange fascination on humans throughout history, and induced sneezing was widely used by physicians for therapeutic purposes, on the ...
Lujain Aloum +3 more
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Transient Receptor Potential Channels and Inflammatory Bowel Disease
Frontiers in Immunology, 2020 The transient receptor potential (TRP) cation channels are present in abundance across the gastrointestinal (GI) tract, serving as detectors for a variety of stimuli and secondary transducers for G-protein coupled receptors.
Yiding Chen +8 more
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, 2021 The transient receptor potential (TRP) superfamily of ion channels is involved in the molecular mechanisms that mediate neuroimmune interactions and activities.
Du Preez, S +3 more
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mSphere, 2023 Transient receptor potential (TRP) channels are evolutionarily conserved integral membrane proteins. They serve as crucial mediators of sensory signals and have profound effects on cellular functions.
Hongchen Wang +3 more
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The role of transient receptor potential channels in metastasis
Biomedicine & Pharmacotherapy, 2023 Metastasis is the hallmark of failed tumor treatment and is typically associated with death due to cancer. Transient receptor potential (TRP) channels affect changes in intracellular calcium concentrations and participate at every stage of metastasis.
Suwen, Bai +8 more
openaire +2 more sources