Results 21 to 30 of about 388,294 (261)
Remedia Sternutatoria over the Centuries: TRP Mediation
Molecules, 2021 Sneezing (sternutatio) is a poorly understood polysynaptic physiologic reflex phenomenon. Sneezing has exerted a strange fascination on humans throughout history, and induced sneezing was widely used by physicians for therapeutic purposes, on the ...
Lujain Aloum +3 more
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Transient Receptor Potential Channels and Inflammatory Bowel Disease
Frontiers in Immunology, 2020 The transient receptor potential (TRP) cation channels are present in abundance across the gastrointestinal (GI) tract, serving as detectors for a variety of stimuli and secondary transducers for G-protein coupled receptors.
Yiding Chen +8 more
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mSphere, 2023 Transient receptor potential (TRP) channels are evolutionarily conserved integral membrane proteins. They serve as crucial mediators of sensory signals and have profound effects on cellular functions.
Hongchen Wang +3 more
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The role of transient receptor potential channels in metastasis
Biomedicine & Pharmacotherapy, 2023 Metastasis is the hallmark of failed tumor treatment and is typically associated with death due to cancer. Transient receptor potential (TRP) channels affect changes in intracellular calcium concentrations and participate at every stage of metastasis.
Suwen, Bai +8 more
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X-ray induces mechanical and heat allodynia in mouse via TRPA1 and TRPV1 activation
Molecular Pain, 2019 Radiotherapy-related pain is a common adverse reaction with a high incidence among cancer patients undergoing radiotherapy and remarkably reduces the quality of life. However, the mechanisms of ionizing radiation-induced pain are largely unknown. In this
Su Cun-Jin +9 more
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Transient Receptor Potential Channels in the Vasculature
Physiological Reviews, 2015 The mammalian genome encodes 28 distinct members of the transient receptor potential (TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for different ionic species. Multiple TRP channels are present in all cells and are involved in diverse aspects of cellular function, including sensory perception and signal transduction.
Scott, Earley, Joseph E, Brayden
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The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature
Frontiers in Immunology, 2017 Canonical or classical transient receptor potential channel 6 (TRPC6) is a Ca2+-permeable non-selective cation channel that is widely expressed in the heart, lung, and vascular tissues.
Monika Malczyk +8 more
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Molecular Mechanisms of Dicentra Formosa’s Analgesic Effect
Medicine in Drug Discovery, 2020 Background: Surgeons, Native Americans, and Eclectics have all sworn to the multiple healing properties including anthelmintic, analgesic, and anti-cancer effects that Dicentra Formosa possesses.
Royale Gray-Lee, Jesun Lee
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Frontiers in Molecular Neuroscience, 2022 Primary afferent neurons of the dorsal root ganglia (DRG) transduce peripheral nociceptive signals and transmit them to the spinal cord. These neurons also mediate analgesic control of the nociceptive inputs, particularly through the μ-opioid receptor ...
Wenting Ma +8 more
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Frontiers in Pharmacology, 2019 The sigma 1 receptor (σ1R) and the mu-opioid receptor (MOR) regulate the transient receptor potential (TRP) V1 calcium channel. A series of proteins are involved in the cross-regulation between MORs and calcium channels like the glutamate N-methyl-D ...
Elsa Cortés-Montero +4 more
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