Results 11 to 20 of about 399,869 (302)

Transient receptor potential ion channels and cerebral stroke

open access: yesBrain and Behavior, 2023
Methods The databases Pubmed, and the National Library of Medicine were searched for literature. All papers on celebral stroke and transient receptor potential ion channels were considered.
Qin'yi Xu   +4 more
doaj   +2 more sources

Transient Receptor Potential Channels in Cardiovascular and Renal Diseases

open access: yesCells, 2022
Transient receptor potential (TRP) channels belong to a superfamily of integral membrane proteins with diverse functions in sensory perception and cellular physiology [...]
Shuangtao Ma, Michael X. Zhu
doaj   +2 more sources

Role of the transient receptor potential vanilloid 1 in inflammation and sepsis

open access: yesJournal of Inflammation Research, 2011
Isabel Devesa1, Rosa Planells-Cases2, Gregorio Fernández-Ballester1, José Manuel González-Ros1, Antonio Ferrer-Montiel1, Asia Fernández-Carvajal11Instituto de Biología Molecular y Celular ...
Devesa I   +5 more
doaj   +1 more source

Transient Receptor Potential (TRP) Channels in Health and Disease

open access: yesCells, 2019
Almost 25 years ago, the first mammalian transient receptor potential (TRP) channel, now named TRPC1, was cloned and published (reviewed in [...]
Alexander Dietrich
doaj   +2 more sources

Transient receptor potential channels’ genes forecast cervical cancer outcomes and illuminate its impact on tumor cells [PDF]

open access: yesFrontiers in Genetics
Introduction: In recent years, there has been a strong association between transient receptor potential (TRP) channels and the development of various malignancies, drug resistance, and resistance to radiotherapy.
Shan Jiang   +10 more
doaj   +2 more sources

Thermosensory Transient Receptor Potential Ion Channels and Asthma

open access: yesBiomedicines, 2021
Asthma is a widespread chronic disease of the bronchopulmonary system with a heterogeneous course due to the complex etiopathogenesis. Natural-climatic and anthropogenic factors play an important role in the development and progression of this pathology.
Oxana Yu. Kytikova   +5 more
doaj   +1 more source

Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4 [PDF]

open access: yesEuropean Cells & Materials, 2021
The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis ...
JW Snuggs, RAD Bunning, CL Le Maitre
doaj   +1 more source

Dysfunction of transient receptor potential ion channels as an important pathophysiological mechanism in asthma

open access: yesRussian Open Medical Journal, 2020
Asthma is a chronic heterogeneous disease characterized by chronic inflammation and bronchial hyperreactivity. Neurogenic inflammation is one of the important causes of hyperreactivity.
Oxana Y. Kytikova   +4 more
doaj   +1 more source

Human UDP-glucuronosyltransferase UGT1A4 forms tertiary N-glucuronides predominately with the energetically less favored tautomer of substituted 1H-indazole (benzpyrazole)

open access: yesJournal of Analytical Science and Technology, 2017
Background Human UDP-glucuronosyltransferase UGT1A4 is reported to convert a range of tertiary amine substrates to the respective quaternary glucuronides. In this study, we report on the in vitro glucuronidation of a substituted 1H-indazole (benzpyrazole)
Andreas Fredenhagen   +4 more
doaj   +1 more source

The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances

open access: yesFrontiers in Molecular Neuroscience, 2022
Menthol is an important flavoring additive that triggers a cooling sensation. Under physiological condition, low to moderate concentrations of menthol activate transient receptor potential cation channel subfamily M member 8 (TRPM8) in the primary ...
Ziping Li   +7 more
doaj   +1 more source

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