Results 71 to 80 of about 157,767 (395)
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Angewandte Chemie, EarlyView.This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich +7 more
wiley +2 more sources
Molecules, 2019 Members of the polo-like kinase (Plk) family of serine/threonine protein kinases play crucial roles in cell cycle regulation and proliferation. Of the five Plks (Plk1–5), Plk1 is recognized as an anticancer drug target.
Xue Zhi Zhao +3 more
doaj +1 more source
N-[(E)-Quinolin-2-ylmethylidene]-1,2,4-triazol-4-amine hemihydrate
IUCrData, 2020 The title hemihydrate, C12H9N5·0.5H2O, was isolated from the condensation reaction of quinoline-2-carbaldehyde with 4-amino-4H-1,2,4-triazole. The Schiff base molecule adopts an E configuration about the C=N bond and is approximately planar, with a ...
Nurulizzatul Ningsheh M. Shahri +6 more
doaj +1 more source
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for propiconazole according to Article 12 of Regulation (EC) No 396/2005 [PDF]
EFSA Journal, 2015 According to Article 12 of Regulation (EC) No 396/2005, the European Food Safety Authority (EFSA) has reviewed the Maximum Residue Levels (MRLs) currently established at European level for the pesticide active substance propiconazole.
European Food Safety Authority
doaj +1 more source
Enantioselective synthesis of (+)-petromyroxol, enabled by rhodium-catalyzed denitrogenation and rearrangement of a 1-sulfonyl-1,2,3-triazole [PDF]
, 2015 Petromyroxol is a non-racemic mixture of enantiomeric oxylipids isolated from water conditioned with larval sea lamprey. The (+)-antipode exhibits interesting biological properties but only 1 mg was isolated from >100000 L of water.
Boyer, Alistair
core +2 more sources
Synthesis and biological evaluation of quinoline-triazole and quinolone-triazole conjugates
TURKISH JOURNAL OF CHEMISTRY, 2018 One-pot synthesis of novel quinoline- and quinolone-substituted 1,2,3-triazoles has been performed from the key intermediates, quinoline- and quinolone-substituted propargyl derivatives 1-3 (48%-88% yields). The antioxidant properties of the newly synthesized compounds, 1a-1c, 2a-2c , and 3a-3c , were evaluated by monitoring DPPH (2,2-diphenyl-1 ...
Ayşegül GÜMÜŞ, Veysi OKUMUŞ
openaire +3 more sources
Mechanisms of Triazole Resistance in Aspergillus fumigatus.
Environmental Microbiology, 2020 The ubiquitous fungal pathogen Aspergillus fumigatus is the primary cause of opportunistic mold infections in humans. Aspergilli disseminate via asexual conidia passively traveling through air currents to germinate within a broad range of environs ...
Ashley V. Nywening +3 more
semanticscholar +1 more source
Supramolecular Chemistry in Metal–Organic Framework Materials
Advanced Materials, EarlyView.This review highlights synergies between reticular chemistry and supramolecular chemistry. The role of supramolecular interactions in determining framework…guest interactions and attempts to understand dynamic behavior in metal–organic frameworks (MOFs), particularly emphasizing the development of crystal sponges, studying reactions in frameworks and ...
Eugenia Miguel‐Casañ +3 more
wiley +1 more source
Supramolecular Gels as Active Tools for Reaction Engineering
Angewandte Chemie, EarlyView.The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley +2 more sources