Results 111 to 120 of about 49,489 (310)
mSphere, 2017 Isavuconazole (ISZ) is a newly available broad-spectrum triazole agent recently approved for the treatment of both invasive aspergillosis and mucormycosis. The aim of this study was to develop a simple and reliable method for therapeutic drug monitoring (
René Jørgensen +3 more
doaj +1 more source
Evaluation of some functionalized imidazoles and 1,2,4-triazoles as antioxidant additives for industrial lubricating oils and correlating the results with the structures of additives using empirical AM1 calculations [PDF]
, 2014 Functionalized 4,5-diphenyl-imidazoles, 4,5-diphenyl-1,2,4-triazoles and 5-(o-hydroxyphenyl)-4-phenyl-1,2,4-triazoles at the 2-position with thiol, thiomethyl and thiobenzyl groups, have been tested as antioxidant additives for lubricating oils.
Abou-Elnaga, Hamdy H. +5 more
core +1 more source
Synthesis of Novel Triazoles, Tetrazine, Thiadiazoles and Their Biological Activities
Molecules, 2015 An expedient synthesis of novel triazoles, tetrazine and thiadiazoles, using conveniently accessible and commercially available starting materials has been achieved.
Mohammed A. Al-Omair +2 more
doaj +1 more source
Evaluation of Posaconazole Pharmacokinetics in Adult Patients with Invasive Fungal Infection
Biomedicines, 2017 Mortality and morbidity due to invasive fungal infections have increased over the years. Posaconazole is a second-generation triazole agent with an extended spectrum of activity, which shows a high interindividual variability in its plasma levels ...
Sarah Allegra +9 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.An orthogonal click chemistry approach was used to synthesize a series of cationic surfactants. The results show that an optimal balance between positive charges and hydrophobicity is a crucial factor for the improvement of antibacterial properties.
Natalie Hanheiser +8 more
wiley +1 more source
Intramolecular [3+2] Cycloaddition of Fused Azolo-Azepanes from Azido Monosaccharides Derivatives [PDF]
, 2016 Síntesis de bicíclicos compuestos empleando epoxiamidas como material de partida. Obtención de tetrazolo azepanos con posible actividad biológica.Universidad de Málaga.
Calvo-Losada, Saturnino +3 more
core
Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]
, 2016 Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core +3 more sources
Beilstein Journal of Organic Chemistry, 2013 The preparation of novel multi-substituted 1,2,3-triazole-modified β-aminocyclohexanecarboxylic acid derivatives in a simple and efficient continuous-flow procedure is reported. The 1,3-dipolar cycloaddition reactions were performed with copper powder as
Sándor B. Ötvös +4 more
doaj +1 more source
Angewandte Chemie International Edition, EarlyView.Generating functionalized ubiquitin building blocks via expression in E. coli paves the way to different di‐, tri‐, and tetra‐ubiquitin chains. Light‐induced thiol‐ene click reactions, combined with a masking and protection strategy, are harnessed to establish controlled ubiquitin chain assembly and to allow the semisynthesis of site‐selectively ...
Moritz Urschbach +6 more
wiley +1 more source
Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates
Molecules, 2016 2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne–azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-
Brigitta Bodnár +9 more
doaj +1 more source