Results 121 to 130 of about 49,489 (310)

Some aspects of the chemistry of 1,2,3,-triazoles [PDF]

open access: yes, 1987
In a wide rang1ng reaction dimethyl diazomalonate reacted with pr1mary amines to yield the corresponding ammonium salts of 5-hydroxy-I,2,3-triazoles in high yields.
Lennon, Sean Patrick
core  

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]

open access: yes, 2019
Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus   +7 more
core  

Copper Nanoparticles in Click Chemistry [PDF]

open access: yes, 2015
Conspectus: The challenges of the 21st century demand scientific and technological achievements that must be developed under sustainable and environmentally benign practices.
Alonso, Francisco   +2 more
core   +2 more sources

Cumulative Exposure Assessment of Triazole Pesticides [PDF]

open access: yes
In the EFSA opinion on identification of new approaches to assess cumulative and synergistic risks from pesticides to human health a tiered approach for cumulative risk assessment has been proposed.
Boon, P.E.   +4 more
core  

Copper-Catalyzed Synthesis of 4-CF3-1,2,3-Triazoles: An Efficient and Facile Approach via Click Reaction

open access: yesMolecules
Incorporation of a trifluoromethyl group with 1,2,3-triazoles motifs was described. We explored a click reaction approach for regioselective synthesis of 1-susbstituted-4-trifluoromethyl-1,2,3-triazoles in which 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU ...
Tinghong Tang   +5 more
doaj   +1 more source

Discovery of ‘click’ 1,2,3-triazolium salts as potential anticancer drugs

open access: yesRadiology and Oncology, 2016
In order to increase the effectiveness of cancer treatment, new compounds with potential anticancer activities are synthesized and screened. Here we present the screening of a new class of compounds, 1-(2-picolyl)-, 4-(2-picolyl)-, 1-(2-pyridyl)-, and 4-(
Steiner Ivana   +10 more
doaj   +1 more source

Recent developments and challenges in chemical disease control - a review

open access: yesPlant Protection Science, 2015
The use of chemical fungicides to control plant diseases is an integral component of crop management. Although fungicides have been used to good effect in agriculture since the 1940s, the introduction of new fungicides is an essential element to provide ...
Andy LEADBEATER
doaj   +1 more source

ZrCl4-catalyzed C-O bond to C-N bond formation: synthesis of 1,2,3-triazoles and their biological evaluation [PDF]

open access: yes, 2014
A simple and efficient protocol was developed for the synthesis of aryl azides directly from aryl carbinols using ZrCl4as a Lewis acid catalyst. The azides were converted to novel triazoles under click reaction conditions, which were evaluated for their ...
Buddana, S   +5 more
core   +1 more source

Enantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles

open access: yesNature Communications
Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited catalytic ...
Ling-Feng Jiang   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy