Results 81 to 90 of about 38,452 (298)

Physical-chemical properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-il)tio)-1-arylethanons and their reduced systems

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The aim of work is the investigation of properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanones and 2((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanols using modern physical-chemical methods.Materials and ...
O. A. Bihdan
doaj   +1 more source

Novel One-Step Synthesis of Thiazolo[3,2-b]1,2,4-triazoles

open access: yes, 2016
Reactions of chalcones 3a−f with bis(1H-1,2,4-triazolyl) sulfoxide 4 formed the thiazolo[3,2-b]1,2,4-triazoles 5a−f, which resemble closely some previously prepared COX-2 inhibitors.
Peter J. Steel (1724674)   +3 more
core   +1 more source

Die Aza‐Büchner–Curtius–Schlotterbeck‐Reaktion: Selektive Bildung Quartärer Kohlenstoffzentren

open access: yesAngewandte Chemie, EarlyView.
Wir stellen die Aza‐Büchner–Curtius–Schlotterbeck‐(ABCS)‐Reaktion vor: eine milde, katalysatorfreie Methode zur Homologierung von Aryliminen. Im Gegensatz zum traditionellen BCS‐Mechanismus durchläuft das Diazo‐Intermediat eine selektive C─C‐Insertion zur Bildung eines quartären Zentrums.
Simon O. Angerer   +6 more
wiley   +1 more source

Self‐Assembled Pt(II) Complexes Boost Up Stem Cell Proliferation and Accelerate Metamorphosis in Living Organisms

open access: yesAngewandte Chemie, EarlyView.
Pt1, an organometallic platinum‐based complex, act as a modulator of redox homeostasis in cnidarians, regulating cellular functions and life‐cycle dynamics. In Nematostella vectensis, it mitigates oxidative stress, strengthens detox systems and accelerates development.
Giuseppina Tommasini   +13 more
wiley   +2 more sources

A New Multicomponent Multicatalyst Reaction (MC)2R: Chemoselective Cycloaddition and Latent Catalyst Activation for the Synthesis of Fully Substituted 1,2,3-Triazoles

open access: yes, 2016
A multicomponent multicatalyst reaction (MC)2R for constructing fully substituted 1,2,3-triazoles is reported. An application of chemoselectivity and latent catalysis in a sequence of multicatalytic reactions confers control over a number of undesired ...
Mark Lautens (1391935)   +4 more
core   +1 more source

Generation of Functionalized Azepinone Derivatives via a (4 + 3)-Cycloaddition of Vinyl Ketenes and Imino Carbenes Derived from NSulfonyl-triazoles

open access: yes, 2022
An intermolecular RhII-catalyzed, formal (4 + 3)-cycloaddition between vinyl ketenes and N-sulfonyl-1,2,3-triazoles for the construction of azepinone products is described.
Brandon L. Ashfeld (1701802)   +9 more
core   +1 more source

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

open access: yesAngewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean   +3 more
wiley   +1 more source

“Click” Synthesis of Nonsymmetrical Bis(1,2,3-triazoles)

open access: yes, 2010
Unsymmetrically 1,1′-disubstituted 4,4′-bis-1H-1,2,3-triazoles 4 have been prepared from 4-ethynyl-1,2,3-triazoles 5 and azides. Following a “double-click” strategy, two complementary approaches were implemented for the preparation of the key 4 ...
Balentová, Eva   +17 more
core   +1 more source

Copper-Catalyzed AzideAlkyne Cycloaddition of Hydrazoic Acid Formed In Situ from Sodium Azide Affords 4Monosubstituted-1,2,3-Triazoles

open access: yes, 2022
We report a copper-catalyzed cycloaddition of hydrogen azide (hydrazoic acid, HN3) with terminal alkynes to form 4-substituted-1H-1,2,3-triazoles in a sustainable manner.
Martin Gazvoda   +5 more
core   +1 more source

Polyproline: A Synthetic Polypeptide With Unique Properties

open access: yesAngewandte Chemie, EarlyView.
Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec   +3 more
wiley   +2 more sources

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