Synthesis of novel acetylcholinesterase reactivators of isoquinolinic type [PDF]
, 2017 Univerzita Karlova Farmaceutická fakulta v Hradci Králové Katedra organické a bioorganické chemie Kandidát: Miroslava Hozová Školiteľ: PharmDr. Jaroslav Roh, Ph.D. Konzultant: RNDr. Dávid Maliňák, Ph.D.
Hozová, Miroslava
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Dynamique structurale de l'acetylcholinesterase et ses implications dans la conception de réactivateurs [PDF]
, 2015 Acetylcholinesterase (AChE), one of nature fastest enzyme, is the target of multiple toxics,including organophosphate nerve agents (OP). In the first part of this thesis I present thestructure-based development of a new uncharged reactivator, which ...
Santoni, Gianluca
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Review of Possible Therapies in Treatment of Novichoks Poisoning and HAZMAT/CBRNE Approaches: State of the Art. [PDF]
J Clin Med, 2023 Noga M, Michalska A, Jurowski K.
europepmc +1 more source
Novel uncharged triazole salicylaldoxime derivatives as potential acetylcholinesterase reactivators: comprehensive computational study, synthesis and in vitro evaluation. [PDF]
RSC Adv, 2023 Baghersad MH +2 more
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Piridinijevi, imidazolijevi i kinuklidinijevi spojevi: toksičnost i protuotrovno djelovanje naspram nervnim otrovima tabunu i somanu [PDF]
, 2006 This paper discusses the toxicity and antidotal effects of 32 compounds. Screening studies have shown that these compounds combined with atropine are effective antidotes against the organophosphate nerve agents Tabun and/or Soman, having a therapeutic ...
Elsa Reiner, Vera Simeon-Rudolf
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A study of myocardial injury in organophosphorous poisoning. [PDF]
, 2015 Organophosphorous (OP) pesticide self-poisoning is estimated to kill around two lakhs population per year, largely in pacific asian region , majority of incidences takes place in rural populations and is mostly due to impulsion.
Giridharan, V
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Progress in Antidotes (Acetylcholinesterase Reactivators) Against Organophosphorus Pesticides [PDF]
, 2011 Anna Horova +6 more
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Evaluating the use of apache ii score in predicting the severity and clinical outcomes of organophosphorous poisoning. [PDF]
, 2015 This study was done to know the efficacy of APACHE II score in predicting the severity and clinical outcomes of organophosphorous poisoning. METHODOLOGY: Patients admitted to toxicology unit of madras medical college and Rajiv Gandhi government ...
Vivekanandan, A
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Recent developments on oximes to improve the blood brain barrier penetration for the treatment of organophosphorus poisoning: a review. [PDF]
RSC Adv, 2020 Faiz Norrrahim MN +11 more
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A Study on Prognostic Significance of QTc Interval in the Initial ECG of OPC Poisoning Patients [PDF]
, 2015 BACK GROUND: Thanjavur being the rice bowl of Tamilnadu which is surrounded by numerous villages the use of pesticides particularly OPC are higher here. So it is a ideal place to study the clinical profile and prognostic factors in OPC poisoning.
Balamurugan, M
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