Results 1 to 10 of about 10,078 (159)

Trimethylamine N-Oxide (TMAO) and Trimethylamine (TMA) Determinations of Two Hadal Amphipods

Journal of Marine Science and Engineering, 2022
Hadal trenches are a unique habitat with high hydrostatic pressure, low temperature and scarce food supplies. Amphipods are the dominant scavenging metazoan species in this ecosystem.
Qi Liu, Shouwen Jiang, Wenhao Li, Binbin Pan, Qianghua Xu   +4 more
doaj   +2 more sources

Trimethylamine N-Oxide (TMAO) Acts as Inhibitor of Endothelial Nitric Oxide Synthase (eNOS) and Hampers NO Production and Acetylcholine-Mediated Vasorelaxation in Rat Aortas [PDF]

Antioxidants
Trimethylamine N-oxide (TMAO) is an endogenous osmolyte produced by enzymatic reactions starting in the human gut, where microbiota release trimethylamine (TMA) from foods, and ending in the liver, where TMA is oxidized to TMAO by flavin-containing ...
Alma Martelli, Federico Abate, Michele Roggia, Giada Benedetti, Eugenio Caradonna, Vincenzo Calderone, Gian Carlo Tenore, Sandro Cosconati, Ettore Novellino, Mariano Stornaiuolo   +9 more
doaj   +2 more sources

Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential

Российский кардиологический журнал, 2022
Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
doaj   +1 more source

The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review

Biomolecules & Biomedicine, 2023
Current research supports the evidence that the gut microbiome (GM), which consist of gut microbiota and their biologically active metabolites, is associated with atherosclerosis development.
Yudi Her Oktaviono, Ariikah Dyah Lamara, Pandit Bagus Tri Saputra, Jannatin Nisa Arnindita, Diar Pasahari, Mahendra Eko Saputra, Ni Made Adnya Suasti   +6 more
doaj   +1 more source

Computational Study of Selected Amine and Lactam N-Oxides Including Comparisons of N-O Bond Dissociation Enthalpies with Those of Pyridine N-Oxides

Molecules, 2020
A computational study of the structures and energetics of amine N-oxides, including pyridine N-oxides, trimethylamine N-oxide, bridgehead bicyclic amine N-oxides, and lactam N-oxides, allowed comparisons with published experimental data.
Arthur Greenberg, Alexa R. Green, Joel F. Liebman   +2 more
doaj   +1 more source

No effect of plasma trimethylamine N-Oxide (TMAO) and plasma trimethyllysine (TML) on the association between choline intake and acute myocardial infarction risk in patients with stable angina pectoris

Human Nutrition & Metabolism, 2020
Plasma concentrations of trimethylamine N-oxide (TMAO) have been linked to cardiovascular disease (CVD) risk and mortality. TMAO is formed through the bacterial conversion of trimethylamine which is obtained either directly from food, generated from ...
Anthea Van Parys, Vegard Lysne, Jannike Øyen, Jutta Dierkes, Ottar Nygård   +4 more
doaj   +1 more source

The ability of trimethylamine N-oxide to resist pressure induced perturbations to water structure

Communications Chemistry, 2022
Trimethylamine N-oxide (TMAO) protects organisms from the damaging effects of deep-sea high pressure, but it is not well understood how pressure and TMAO in combination perturb the water structure.
Harrison Laurent, Tristan G. A. Youngs, Thomas F. Headen, Alan K. Soper, Lorna Dougan   +4 more
doaj   +1 more source

Gut Microbiota and Ischemic Stroke: The Role of Trimethylamine N-Oxide [PDF]

Journal of Stroke, 2019
Trimethylamine N-oxide (TMAO) is produced when trimethylamine, a waste product of gut microbes, is converted via hepatic flavin monooxygenases. As TMAO is a potential causative factor in various cardiovascular diseases (CVDs) considerable research ...
Hyo Suk Nam
doaj   +1 more source

Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention

Biosensors, 2021
The gut microbiota plays a critical role in chronic kidney disease (CKD) and hypertension. Trimethylamine-N-oxide (TMAO) and trimethylamine (TMA) are gut microbiota-derived metabolites, and both are known uraemic toxins that are implicated in CKD ...
Yu-Chun Chang, Yi-Hsuan Chu, Chien-Cheng Wang, Chih-Hsuan Wang, You-Lin Tain, Hung-Wei Yang   +5 more
doaj   +1 more source

TMAO metaorganismal pathway and chronic inflammatory diseases [PDF]

Exploration of Medicine
Nutrients containing a trimethylamine (TMA) moiety in their structure can be metabolized by the gut microbiota through enzymatic cleavage of the C-N bond, producing TMA.
Zeneng Wang, Shumei Man, Robert Koeth
doaj   +1 more source