Results 41 to 50 of about 4,753,527 (236)

DataSheet_1_Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria.zip

, 2022
Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill Plasmodium-infected cells. A new malaria vaccine strategy, prime-target vaccination, involves sequential viral-vectored vaccination by intramuscular and ...
Jonathan Sheridan (12052670), Rebecca A. Makinson (12052664), Richard Morter (4766202), Amy Flaxman (12052658), Alexandra J. Spencer (12052676), Mehreen S. Datoo (12052655), Duncan Bellamy (11408480), Adrian V. S. Hill (8955395), Dimitrios Voukantsis (12052673), Daniel Jenkin (12052661), Mohammad Ali Husainy (7600742), Katie J. Ewer (7946855), Fernando Ramos Lopez (12052667), Andrés Noé (3620534), Naveen Prasad (11239158)   +14 more
core   +1 more source

A molecular signature of lung-resident CD8+ T cells elicited by subunit vaccination

Scientific Reports, 2022
Natural infection as well as vaccination with live or attenuated viruses elicit tissue resident, CD8+ memory T cell (Trm) response. Trm cells so elicited act quickly upon reencounter with the priming agent to protect the host.
Naveenchandra Suryadevara, Amrendra Kumar, Xiang Ye, Meredith Rogers, John V. Williams, John T. Wilson, John Karijolich, Sebastian Joyce   +7 more
doaj   +1 more source

Table_3_HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.xlsx

, 2022
Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (TRM) CD8+ T-cells is of great ...
Alex K. Shalek (1291083), Osaretin E. Asowata (11777852), Warren Kuhn (5740346), Bonnie Berger (19458), Philip Goulder (87977), Søren Buus (49944), J. Zachary Porterfield (6904217), Thumbi Ndung’u (159362), Jennifer Giandhari (9543786), Alasdair Leslie (735478), Samita Singh (13974384), Rishan Bipath (13974390), Frank Anderson (4055212), Son Nguyen (525816), Alveera Singh (9442604), Abigail Ngoepe (5740340), Farina Karim (2577766), Andile L. Sibiya (13974387), Dirhona Ramjit (8858981), Kumeshan Moodley (13974393), Ntombifuthi Mthabela (13974381), Sarah K. Nyquist (13777944), Rabiah Fardoos (4678399), Tulio de Oliveira (68362), Henrik N. Kløverpris (9440270), Samuel W. Kazer (1870930)   +25 more
core   +1 more source

Table_1_HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.xlsx

, 2022
Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (TRM) CD8+ T-cells is of great ...
Alex K. Shalek (1291083), Osaretin E. Asowata (11777852), Warren Kuhn (5740346), Bonnie Berger (19458), Philip Goulder (87977), Søren Buus (49944), J. Zachary Porterfield (6904217), Thumbi Ndung’u (159362), Jennifer Giandhari (9543786), Alasdair Leslie (735478), Samita Singh (13974384), Rishan Bipath (13974390), Frank Anderson (4055212), Son Nguyen (525816), Alveera Singh (9442604), Abigail Ngoepe (5740340), Farina Karim (2577766), Andile L. Sibiya (13974387), Dirhona Ramjit (8858981), Kumeshan Moodley (13974393), Ntombifuthi Mthabela (13974381), Sarah K. Nyquist (13777944), Rabiah Fardoos (4678399), Tulio de Oliveira (68362), Henrik N. Kløverpris (9440270), Samuel W. Kazer (1870930)   +25 more
core   +1 more source

CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver

Cell Reports, 2018
Summary: Liver tissue-resident memory T (Trm) cells migrate throughout the sinusoids and are capable of protecting against malaria sporozoite challenge.
Lauren E. Holz, Julia E. Prier, David Freestone, Thiago M. Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I. Godfrey, Katsuyuki Yui, Laura K. Mackay, Mireille H. Lahoud, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R. Heath   +17 more
doaj   +1 more source

Distribution, phenotype and dysfunctional mechanism of CD8+ CD103+ tissue-resident memory T cells in gastric cancer patients

Di-san junyi daxue xuebao, 2021
Objective To investigate the distribution and phenotypic features of CD8+CD103+ tissue-resident memory T cells (Trm) in gastric cancer (GC) patients, and to explore their dysfunctional mechanism.
SHEN Yang, PENG Liusheng, QIU Yuan, ZOU Quanming, MA Daiyuan   +4 more
doaj   +1 more source

Table_9_HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.xlsx

, 2022
Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (TRM) CD8+ T-cells is of great ...
Alex K. Shalek (1291083), Osaretin E. Asowata (11777852), Warren Kuhn (5740346), Bonnie Berger (19458), Philip Goulder (87977), Søren Buus (49944), J. Zachary Porterfield (6904217), Thumbi Ndung’u (159362), Jennifer Giandhari (9543786), Alasdair Leslie (735478), Samita Singh (13974384), Rishan Bipath (13974390), Frank Anderson (4055212), Son Nguyen (525816), Alveera Singh (9442604), Abigail Ngoepe (5740340), Farina Karim (2577766), Andile L. Sibiya (13974387), Dirhona Ramjit (8858981), Kumeshan Moodley (13974393), Ntombifuthi Mthabela (13974381), Sarah K. Nyquist (13777944), Rabiah Fardoos (4678399), Tulio de Oliveira (68362), Henrik N. Kløverpris (9440270), Samuel W. Kazer (1870930)   +25 more
core   +1 more source

DataSheet_1_HIV specific CD8+ TRM-like cells in tonsils express exhaustive signatures in the absence of natural HIV control.docx

, 2022
Lymphoid tissues are an important HIV reservoir site that persists in the face of antiretroviral therapy and natural immunity. Targeting these reservoirs by harnessing the antiviral activity of local tissue-resident memory (TRM) CD8+ T-cells is of great ...
Alex K. Shalek (1291083), Osaretin E. Asowata (11777852), Warren Kuhn (5740346), Bonnie Berger (19458), Philip Goulder (87977), Søren Buus (49944), J. Zachary Porterfield (6904217), Thumbi Ndung’u (159362), Jennifer Giandhari (9543786), Alasdair Leslie (735478), Samita Singh (13974384), Rishan Bipath (13974390), Frank Anderson (4055212), Son Nguyen (525816), Alveera Singh (9442604), Abigail Ngoepe (5740340), Farina Karim (2577766), Andile L. Sibiya (13974387), Dirhona Ramjit (8858981), Kumeshan Moodley (13974393), Ntombifuthi Mthabela (13974381), Sarah K. Nyquist (13777944), Rabiah Fardoos (4678399), Tulio de Oliveira (68362), Henrik N. Kløverpris (9440270), Samuel W. Kazer (1870930)   +25 more
core   +1 more source

Local Inflammatory Cues Regulate Differentiation and Persistence of CD8+ Tissue-Resident Memory T Cells

Cell Reports, 2017
Many pathogens initiate infection at mucosal surfaces, and tissue-resident memory T (Trm) cells play an important role in protective immunity, yet the tissue-specific signals that regulate Trm differentiation are poorly defined. During Yersinia infection,
Tessa Bergsbaken, Michael J. Bevan, Pamela J. Fink   +2 more
doaj   +1 more source

DataSheet_3_Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria.docx

, 2022
Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill Plasmodium-infected cells. A new malaria vaccine strategy, prime-target vaccination, involves sequential viral-vectored vaccination by intramuscular and ...
Jonathan Sheridan (12052670), Rebecca A. Makinson (12052664), Richard Morter (4766202), Amy Flaxman (12052658), Alexandra J. Spencer (12052676), Mehreen S. Datoo (12052655), Duncan Bellamy (11408480), Adrian V. S. Hill (8955395), Dimitrios Voukantsis (12052673), Daniel Jenkin (12052661), Mohammad Ali Husainy (7600742), Katie J. Ewer (7946855), Fernando Ramos Lopez (12052667), Andrés Noé (3620534), Naveen Prasad (11239158)   +14 more
core   +1 more source