Results 51 to 60 of about 1,246 (105)

Transfer RNA-derived small RNAs (tsRNAs): A rising star in liquid biopsy

Genes and Diseases
Liquid biopsy has emerged as a valuable clinical tool due to its non-invasive nature and real-time molecular profiling capabilities. Transfer RNA-derived small RNAs (tsRNAs) are a group of small non-coding RNAs generated from mature tRNAs or tRNA ...
Qinglin Wang, Zehao Pan, Si Liang, Yuanjian Shi, Gaochao Dong, Lin Xu, Qixing Mao, Feng Jiang   +7 more
doaj   +1 more source

Transfer RNA expression, modification, and derived small RNAs in cancer biology and clinical potential

Frontiers in Immunology
Transfer RNA (tRNA) is essential for protein synthesis and undergoes diverse chemical modifications that regulate its stability and function. Dysregulation of tRNA expression and modifications, along with the activity of tRNA-derived small RNAs (tsRNAs ...
Ming Luo, Ji’an Liu, Yang Su, Rao Fu, Xufeng Huang, Xufeng Huang, Qi Wang, Jing Li, Zhengrui Li, Li Liu   +9 more
doaj   +1 more source

tsRNA, cell death and disease: Connecting the dots

Non-coding RNA Research
Cell death is essential for maintaining physiological homeostasis and regulating pathological processes. tRNA-derived small RNAs (tsRNAs), an emerging non-coding small RNA, play key roles in a various form of cell death.
Xiaoyu Ma, Jiesi Xu, Guoping Li
doaj   +1 more source

The biogenesis, mechanism and function of the tRNA-derived small RNA (tsRNA): a review compared with microRNA.

American journal of cancer research
Since the discovery of the first miRNA in 1993, numerous studies have focused on their biogenesis, their functions on regulating a diversity of cellular processes, and the molecular mechanisms underlying their regulatory activity. The critical roles they play during pathogenesis have also been explored.
Yuxin, Zhao, Xiaofeng, Li, Chong, Ye, Cheng, Huang, Xiongwen, Lv, Jun, Li   +5 more
openaire   +1 more source

Serum exosome smallRNA array analysis identifies 5’tiRNA-PheGAA and tRF-1-IleAAT as potential biomarkers for diagnosis of rheumatoid arthritis

Immunobiology
tRNA-derived small RNAs (tsRNAs) are a recently identified class of non-coding RNAs (ncRNAs) that exhibit aberrant expression in various diseases and are involved in multiple pathological processes.
Yuanyuan Li, Meiling Xu, Nan Zhao, Chong Qi, Tingshuang Xu   +4 more
doaj   +1 more source

Role of tRNA-Derived Fragments in Protozoan Parasite Biology

Cells
tRNA molecules are among the most fundamental and evolutionarily conserved RNA types, primarily facilitating the translation of genetic information from mRNA into proteins.
Manu Sharma, Upinder Singh
doaj   +1 more source

Molecular messengers of the brain: tRNA-derived small RNAs at the crossroads of brain development and neurodevelopmental disorders

Neurobiology of Disease
Brain development is tightly regulated by different modulators and mechanisms. Disruptions in these processes underlie a spectrum of neurodevelopmental disorders.
Renqiuguo Li, Xiao Li, Hao Wang, HongYuan Chu, Meiyu Dong, Junjiao Zhang, Kai Gao, Jianxiong Gui, Yuwu Jiang   +8 more
doaj   +1 more source

tRNA-derived small RNAs in ocular neovascular diseases: A systematic review. [PDF]

Noncoding RNA Res
Liu TY, Kuai PZ, Luo YS, Song Y, Wang Y, Huang XB, Cao X.   +6 more
europepmc   +1 more source

Transfer RNA-derived small RNAs (tsRNAs) in Alzheimer's disease: emerging mechanisms and diagnostic potential. [PDF]

Med Rev (2021)
Zhang J, Han J, Liu Q.
europepmc   +1 more source

Biological functions of tsRNAs and research advances in human disease. [PDF]

Biochem Biophys Rep
Jiang Y, Liu S, Li G, Tang C, Zhang Y, Li J, Tan Z, Zhang S, Chen Z, Li S.   +9 more
europepmc   +1 more source