Results 41 to 50 of about 68,298 (102)

Distinct non‐coding RNA cargo of extracellular vesicles from M1 and M2 human primary macrophages

Journal of Extracellular Vesicles, 2022
Macrophages are important antigen presenting cells which can release extracellular vesicles (EVs) carrying functional cargo including non‐coding RNAs. Macrophages can be broadly classified into M1 ‘classical’ and M2 ‘alternatively‐activated’ macrophages.
Paschalia Pantazi, Toby Clements, Morten Venø, Vikki M. Abrahams, Beth Holder   +4 more
doaj   +1 more source

tRNA-Derived Fragments as Novel Predictive Biomarkers for Trastuzumab-Resistant Breast Cancer

Cellular Physiology and Biochemistry, 2018
Background/Aims: Resistance to trastuzumab remains a common challenge to HER-2 positive breast cancer. Up until now, the underlying mechanism of trastuzumab resistance is still unclear.
Chunxiao Sun, Fan Yang, Yanhong Zhang, Jiahui Chu, Jian Wang, Yifan Wang, Yanqiu Zhang, Jun Li, Yongfei Li, Ruihua Fan, Wei Li, Xiang Huang, Hao Wu, Ziyi Fu, Zefei Jiang, Yongmei Yin   +15 more
doaj   +1 more source

A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance

Biomolecules, 2018
tRNA-derived fragments (tRFs) are a new class of non-coding RNA that play an important role in regulating cellular RNA processing and protein translation. However, there is currently no study reporting the influence of tRFs on myocardial hypertrophy.
Linyuan Shen, Mailin Gan, Zhengdong Tan, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Jinyong Wang, Xuewei Li, Shunhua Zhang, Li Zhu   +9 more
doaj   +1 more source

Role of tRNA-Derived Fragments in Protozoan Parasite Biology

Cells
tRNA molecules are among the most fundamental and evolutionarily conserved RNA types, primarily facilitating the translation of genetic information from mRNA into proteins.
Manu Sharma, Upinder Singh
doaj   +1 more source

Protocol for rapid tRNA enrichment and chemiluminescent northern blot detection of tRNA and tRNA-derived fragments

STAR Protocols
Summary: Transfer RNA (tRNA), its post-transcriptional modifications, and tRNA-derived fragments (tRFs) play essential roles in cellular processes and gene regulation.
Pavlina Gregorova, Minna-Maria K. Heinonen, Milla M. Laarne, L. Peter Sarin   +3 more
doaj   +1 more source

Transfer RNA and Origins of RNA Interference

Frontiers in Molecular Biosciences, 2021
Andrey Grigoriev
doaj   +1 more source

Hidden in plain sight: illuminating the tRNA landscape by sequencing

Genome Biology
Transfer RNAs (tRNAs) are essential for decoding mRNAs into proteins and are increasingly recognized as dynamic regulators of gene expression. Their function is shaped by intricate layers of post-transcriptional processing, modification, aminoacylation ...
Katherine Marlow, Zhangli Su
doaj   +1 more source

Molecular investigation of tRNA genes integrity and its relation to pathogenicity islands in Shiga toxin-producing Escherichia coli (STEC) strains

Genetics and Molecular Biology, 2004
tRNA genes are known target sites for the integration of pathogenicity islands (PAI) and other genetic elements, such as bacteriophages, into bacterial genome. In most STEC (Shiga toxin-producing Escherichia coli), the PAI called LEE (locus of enterocyte
Rogério Carlos Novais, Marcela Cassin Chaves, Alice Gonçalves Martins Gonzalez, João Ramos Costa Andrade   +3 more
doaj   +1 more source

Stress-induced tRNA fragments take action in alternative splicing in Arabidopsis. [PDF]

Plant Physiol, 2023
Cao D.
europepmc   +1 more source

The Fate and Functionality of Alien tRNA Fragments in Culturing Medium and Cells of Escherichia coli. [PDF]

Int J Mol Sci, 2023
Shavkunov KS, Markelova NY, Glazunova OA, Kolzhetsov NP, Panyukov VV, Ozoline ON.   +5 more
europepmc   +1 more source