Results 111 to 120 of about 44,311 (250)

Arterial–venous differences of brain‐derived neurotrophic factor isoforms across the brain and muscle after exercise at different intensities

The Journal of Physiology, EarlyView.
Abstract figure legend Exercise‐induced increases in forearm venous plasma and serum brain‐derived neurotrophic factor (BDNF) are often assumed to be indicative of release from the brain. Sixteen healthy and physically fit adults (20–40 years old) were recruited to investigate whether exercise‐induced changes in forearm venous mature BDNF (mBDNF) and ...
Olga Tarassova, Yiwen Jiang, Helena Wallin, Mats Jensen‐Urstad, Nikola Drca, Julia Röja, Marjan Pontén, Abram Katz, Jonna Nilsson, Maria M. Ekblom, Marcus Moberg   +10 more
wiley   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Motor properties of Myosin 5c are modulated by tropomyosin isoforms and inhibited by pentabromopseudilin

Frontiers in Physiology
Myosin 5c (Myo5c) is a motor protein that is produced in epithelial and glandular tissues, where it plays an important role in secretory processes. Myo5c is composed of two heavy chains, each containing a generic motor domain, an elongated neck domain ...
András Kengyel, András Kengyel, Philip M. Palarz, Jacqueline Krohn, Anja Marquardt, Johannes N. Greve, Robin Heiringhoff, Anne Jörns, Dietmar J. Manstein   +8 more
doaj   +1 more source

Role of Tpm Isoforms Produced by the TPM4 Gene in the Regulation of Actin Filament Dynamics by Cofilin

Biomolecules
The actin cytoskeleton determines a huge number of intracellular processes, as well as maintaining the cell shape, transport, formation of intercellular contacts, etc.
Svetlana G. Roman, Victoria V. Nefedova, Alexander M. Matyushenko   +2 more
doaj   +1 more source

Induction of Shrimp Tropomyosin-Specific Hypersensitivity in Mice

, 2009
Background: Shellfish hypersensitivity is amongst the most common food allergies. The major shellfish allergen was identified as tropomyosin. Here, we investigated the immediate hypersensitivity responses, IgE and cell-mediated immune response in mice ...
莊雅惠;江伯倫, Leung, Patrick S.C.; Lee, Yuen Shan; Tang, Chi Yan; Kung, Wing Yee; Chuang, Ya-Hui; Chiang, Bor-Luen; Fung, Ming Chiu; Chu, Ka Hou   +1 more
core   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

A Combination of Alleles in LMOD2 and a lncRNA is Strongly Associated With Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT A previous genome‐wide association study identified regions on canine chromosome (cfa) 13 and 14 associated with early onset myxomatous mitral valve disease (MMVD) in Cavalier King Charles Spaniels (CKCS). In the present study, whole genome sequencing (WGS) of 9 CKCS cases (mitral regurgitation (MR) before 4.5 years or congestive heart failure
Lisbeth Høier Olsen, Arney Eva Gunnlaugsdóttir, Majbritt Busk Madsen, Isabella Jane Larsen, Maria Josefine Ubbe Reimann, Foteini Papadaki, Ingrid Ljungvall, Jens Häggström, Torben Martinussen, Henrik Duelund Pedersen, Torkel Falk, Merete Fredholm, Peter Karlskov‐Mortensen   +12 more
wiley   +1 more source

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source

Gamma Delta T Cells in Shrimp Allergy Express a Unique Cytotoxic Cytokine Profile

Clinical and Translational Allergy
Shellfish allergy is the most common food allergy in adults and the third most common in children. γδ T cells have been identified as playing a critical role in antigen tolerance in allergic diseases in mouse models.
Brenda Bin Su, Tyler Jackson, Warren Blackmon, Harold Ames, Christopher Holt, Aikaterini Anagnostou, Vibha Szafron, Sara Anvari, Hongjie Li, Carla M. Davis   +9 more
doaj   +1 more source

Vertebrate Tropomyosin as an Allergen [PDF]

Journal of Investigational Allergology and Clinical Immunology, 2018
S, Peixoto, T, Monteiro, M, Carvalho, M, Santos, C, Matos, B, Bartolomé, M, Labrador-Horrillo, M, Quaresma   +7 more
openaire   +2 more sources