Results 11 to 20 of about 43,019 (192)

Effect of structural stability on endolysosomal degradation and T‐cell reactivity of major shrimp allergen tropomyosin

open access: yesbioRxiv, 2020
Background Tropomyosins are highly conserved proteins, an attribute that forms the molecular basis for their IgE antibody cross-reactivity. Despite structural similarities, their allergenicity varies greatly between ingested and inhaled invertebrate ...
S. Kamath   +17 more
semanticscholar   +1 more source

Multisyringe Flow Injection Analysis of Tropomyosin Allergens in Shellfish Samples

open access: yesMolecules, 2021
This paper presents the development and the application of a multisyringe flow injection analysis system for the fluorimetric determination of the major heat-stable known allergen in shrimp, rPen a 1 (tropomyosin).
Bruno Coulomb   +4 more
doaj   +1 more source

Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer

open access: yesAnnals of Oncology, 2019
The tropomyosin receptor kinase (TRK) family of receptor tyrosine kinases are encoded by NTRK genes and have a role in the development and normal functioning of the nervous system. Since the discovery of an oncogenic NTRK gene fusion in colorectal cancer
A. Amatu   +5 more
semanticscholar   +1 more source

cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction

open access: yesRespiratory Research, 2018
Background The nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains ...
Lihui Zou   +7 more
doaj   +1 more source

In Silico Prediction of Cross-Reactive Epitopes of Tropomyosin from Shrimp and Other Arthropods Involved in Allergy

open access: yesMolecules, 2022
Tropomyosin in shellfish is considered a major cross-reactive allergen in house dust mites and cockroaches; however, the specific epitopes have not been elucidated. Therefore, this study aimed to identify the consensus antigenic determinant among shrimp,
Jirakrit Saetang   +2 more
doaj   +1 more source

Effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages containing chitosan, by the ELISA method

open access: yesFood and Agricultural Immunology, 2023
The aim of this study was evaluated the effect of selected bioactive substances and nanoparticles on the immunoreactivity of edible packages based on chitosan using the ELISA. The analysed protein was the tropomyosin.
L. Havlová   +8 more
doaj   +1 more source

Tropomyosin: An Excretory/Secretory Protein from Haemonchus contortus Mediates the Immuno-Suppressive Potential of Goat Peripheral Blood Mononuclear Cells In Vitro

open access: yesVaccines, 2020
During host-parasite interactions, binding of excretory/secretory proteins (ESPs) on the host immune cells is considered the fundamental phase for regulation of immune responses.
Muhammad Ehsan   +9 more
doaj   +1 more source

Molecular Investigation of the Impact of Thermal Processing Techniques on Tropomyosin Crustacean Allergens

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2023
While shellfish species are widely consumed due to their nutritional advantages, they are also among the top eight food items for food-borne allergies.
Elif Tuğçe Aksun Tümerkan
doaj   +1 more source

Structural Characteristics, Binding Partners and Related Diseases of the Calponin Homology (CH) Domain

open access: yesFrontiers in Cell and Developmental Biology, 2020
The calponin homology (CH) domain is one of the most common modules in various actin-binding proteins and is characterized by an α-helical fold. The CH domain plays important regulatory roles in both cytoskeletal dynamics and signaling.
Lei-Miao Yin   +2 more
doaj   +1 more source

Thin filament dysfunctions caused by mutations in tropomyosin Tpm3.12 and Tpm1.1

open access: yesJournal of Muscle Research and Cell Motility, 2019
Tropomyosin is the major regulator of the thin filament. In striated muscle its function is to bind troponin complex and control the access of myosin heads to actin in a Ca2+-dependent manner.
J. Moraczewska
semanticscholar   +1 more source

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