Results 61 to 70 of about 57,485 (298)

Age-Related Differences in Vancomycin-Associated Nephrotoxicity and Efficacy in Methicillin-Resistant Staphylococcus aureus Infection: A Comparative Study between Elderly and Adult Patients

Antibiotics
Elderly patients (age ≥ 65 years) are susceptible to methicillin-resistant Staphylococcus aureus (MRSA) infections, with potential for more adverse treatment outcomes or complications compared to younger adults (18–64 years).
Lin Xi, Shanshan Li, Mengting Chen, Xiaolan Huang, Nanyang Li, Nanye Chen, Hailan Wu, Qiyu Bian, Xingchen Bian, Xin Li, Minjie Yang, Xiaoyu Liang, Jufang Wu, Beining Guo, Yaxin Fan, Jing Zhang   +15 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Individualized Vancomycin Dosing with Therapeutic Drug Monitoring and Pharmacokinetic Consultation Service: A Large-Scale Retrospective Observational Study

Drug Design, Development and Therapy, 2021
Sang-Mi Kim,1 Hyun-Seung Lee,1 Na-Young Hwang,2 Kyunga Kim,2 Hyung-Doo Park,1 Soo-Youn Lee1,3,4 1Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; 2Statistics and Data Center,
Kim SM, Lee HS, Hwang NY, Kim K, Park HD, Lee SY   +5 more
doaj  

From parabolic-trough to metasurface-concentrator

, 2017
Metasurfaces are promising tools towards novel designs for flat optics applications. As such their quality and tolerance to fabrication imperfections need to be evaluated with specific tools. However, most such tools rely on the geometrical optics approximation and are not straightforwardly applicable to metasurfaces.
Hsu, LiYi, Dupré, Matthieu, Ndao, Abdoulaye, Kanté, Boubacar   +3 more
openaire   +2 more sources

Cumulative prevalence of grade II-IV acute GvHD in patients with a trough CsA concentration <350 ng/mL (blue; N = 42) versus a trough CsA concentration ≥350 ng/mL (green; N = 87).

, 2019
Cumulative prevalence of grade II-IV acute GvHD in patients with a trough CsA concentration
Elizabeth A. de Kort (6495041), Gerwin Huls (3371285), Nicole M. A. Blijlevens (116011), Heleen S. de Lil (6495044), Walter J. F. M. van der Velden (115990), Roger J. M. Brüggemann (3394553), Lenneke F. J. van Groningen (6495050), Manita E. J. Bremmers (6495047), Suzanne van Dorp (6495053)   +8 more
core   +1 more source

Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy

Advanced Engineering Materials, EarlyView.
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb, Zachary T. Kloenne, Samuel R. Rogers, Chi Hang Dominik Kwok, Mark C. Hardy, Michele S. Conroy, David Dye   +6 more
wiley   +1 more source

Efficacy and toxicity analysis of ganciclovir in patients with cytomegalovirus lung infection: what is new for target range of therapeutic drug monitoring

Microbiology Spectrum
To investigate the relationship between ganciclovir trough concentration and its clinical efficacy and safety in patients with pulmonary cytomegalovirus (CMV) infection and to evaluate the target value of therapeutic drug monitoring (TDM) for predicting ...
Dongjie Guo, Xiaoxing Wang, Pengmei Li, Yongguang Shang, Lei Zhang, Yue Chen, Xudong Kong, Wenqian Chen   +7 more
doaj   +1 more source

A retrospective study to estimate serum vancomycin trough concentrations in pediatric patients with current recommended dosing regimen

Journal of Medical Sciences, 2018
Background: Vancomycin is widely prescribed to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). According to the Infectious Disease Society of America 2011 MRSA guidelines for adults, trough concentrations of 15–20 μg/ml ...
Chia-Ning Chang, Wen-Tsung Lo, Ming-Chin Chan, Chih-Chien Wang   +3 more
doaj   +1 more source

Performance Simulation of Solar Trough Concentrators: Optical and Thermal Comparisons

Energies, 2023
The solar trough concentrator is used to increase the solar radiation intensity on absorbers for water heating, desalination, or power generation purposes. In this study, optical performances of four solar trough concentrators, viz.
Fei Cao, Jiarui Pang, Xianzhe Gu, Miaomiao Wang, Yanqin Shangguan   +4 more
doaj   +1 more source

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

Advanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source