Results 91 to 100 of about 35,537 (259)

Diethylcarbamazine elicits calcium signals by activation of Brugia malayi TRP-2b channels heterologously expressed in HEK293 cells

Scientific Reports
Diethylcarbamazine is a classic anthelmintic that is used for the prevention and treatment of lymphatic filariasis. The mode of action of diethylcarbamazine is still not well understood with the consensus that it acts on the host immune system, rather ...
Paul D. E. Williams, Sudhanva S. Kashyap, Alan P. Robertson, Richard J. Martin   +3 more
doaj   +1 more source

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

Frontiers in Molecular Biosciences
TRP channels play important roles in regulating various physiological and pathological processes, including the progression of cancer. Several TRP channels mediate tumour development.
Yu Zhang, Yanfeng Yi, Yinghao Shu, Xiaochen Ru, Shuaibing He   +4 more
doaj   +1 more source

Molecular pharmacology of the onco-TRP channel TRPV6. [PDF]

Channels (Austin), 2023
Neuberger A, Sobolevsky AI.
europepmc   +1 more source

Enhanced Photocatalytic Antibiotic Micropollutants Removal Resulting From a Synergism Between Cu Single Atoms and Carbon Vacancies on Graphitic Carbon Nitride

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Scheme of the synergistic degradation for antibiotic micropollutants in the Cu/ag‐C3N4 system. Photocatalytic processes driven by visible‐light irradiation offer a sustainable means of micropollutants removal from aquatic environments without the addition of reagents.
Xiaozhe Song, Cong Yan, Qinghua Yan, Congzhe Ren, Xin Liu, Ruiyan Zhang, Lei Chen, Chongqing Xu, Zhouyang Long, Wenyu Wang, Mingming Song, Xiaoguo Shi, Hui Wang   +12 more
wiley   +1 more source

Emerging Role of TRP Channels in Osteoarthritis Pathogenesis

Cells
Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation, synovial inflammation, osteophyte formation, joint space narrowing, and persistent pain.
Shivmurat Yadav, Jyoti Yadav, Mary Beth Humphrey   +2 more
doaj   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, EarlyView.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Primary cilia TRP channel regulates hippocampal excitability. [PDF]

Proc Natl Acad Sci U S A, 2023
Vien TN, Ta MC, Kimura LF, Onay T, DeCaen PG.   +4 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Alleviation of thermal nociception depends on heat-sensitive neurons and a TRP channel in the brain. [PDF]

Curr Biol, 2023
Liu J, Liu W, Thakur D, Mack J, Spina A, Montell C.   +5 more
europepmc   +1 more source