Results 101 to 110 of about 1,264,013 (289)

Structure-function relationship of the TRP channel superfamily [PDF]

open access: yes, 2006
Transient receptor potential (TRP) channels are involved in the perception of a wide range of physical and chemical stimuli, including temperature and osmolarity changes, light, pain, touch, taste and pheromones, and in the initiation of cellular ...
Owsianik, Grzegorz   +3 more
core   +1 more source

TRP Channels in Digestive Tract Cancers. [PDF]

open access: yes, 2020
Cancers of the digestive tract are among the most prevalent types of cancer. These types of cancers are often diagnosed at a late stage, which results in a poor prognosis.
Borgström, Anna   +7 more
core   +2 more sources

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao   +9 more
wiley   +1 more source

TRP-1 and TRP-2 are stretch-sensitive proprioceptive receptors.

open access: yes, 2018
(A) Heat maps and the average turning angle for indicated genotypes. n = 20 for each genotype. (B) Average wave width of the indicated genotypes. n = 50 for each genotype.
Jinmahn Kim (787021)   +9 more
core   +1 more source

Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice

open access: yesAdvanced Science, EarlyView.
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang   +12 more
wiley   +1 more source

Transient receptor potential channels in Flaviviridae infection: A comprehensive review

open access: yesChannels
Diseases caused by Flaviviridae viruses exert profound global health and economic burdens due to their high incidence and associated mortality. Infection by the Flaviviridae family often leads to severe acute or chronic illnesses, including hemorrhagic ...
Fuchun Jiang   +2 more
doaj   +1 more source

Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure

open access: yeseLife, 2018
Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiological ...
Simon Bulley   +12 more
doaj   +1 more source

TRP channels in epileptogenesis: calcium dysregulation mechanisms and pharmacological targeting strategies

open access: yesFrontiers in Molecular Neuroscience
Epilepsy, a prevalent neurological disorder affecting millions globally, manifests as recurrent synchronous neuronal discharges that disrupt normal cerebral function.
Guolong Deng   +16 more
doaj   +1 more source

TRP Channels Entering the Structural Era [PDF]

open access: yes, 2013
Transient receptor potential (TRP) channels are important in many neuronal and non-neuronal physiological processes. The past 2 years have seen much progress in the use of structural biology techniques to elucidate molecular mechanisms of TRP channel ...
Gaudet, Rachelle
core   +1 more source

TRP Channels in Excitotoxicity

open access: yesThe Neuroscientist
Glutamate excitotoxicity is a central mechanism contributing to cellular dysfunction and death in various neurological disorders and diseases, such as stroke, traumatic brain injury, epilepsy, schizophrenia, addiction, mood disorders, Huntington’s disease, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, pathologic pain, and even normal ...
Pengyu Zong   +3 more
openaire   +2 more sources

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