Results 201 to 210 of about 35,655 (260)

Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo   +11 more
wiley   +1 more source

Comparative Neuroanatomy of Hydrothermal Vent Shrimps: Ecological Differentiation Among Four Alvinocaridid Species

open access: yesJournal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Hydrothermal vent shrimps share a conserved brain architecture with enlarged mushroom bodies and terminal medullae, shaped by similar environmental pressures. Despite this similarity, some anatomical features near the brain vary between species, suggesting that some ecological factors, such as microhabitat and trophic strategies, also influence nervous
Adrien Mathou   +5 more
wiley   +1 more source

Heart‐Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Selective purification of heart‐specific spinal and vagal sensory neurons by retrograde labeling and FACS purification showed enhanced spontaneous, optogenetic, and chemically stimulated Ca2+ activity. Transcriptomic profiling identified distinct ion channel and GPCR signatures in heart‐specific sensory neurons.
T. Akgul Caglar   +8 more
wiley   +1 more source

Microfluidic nanochips for rapid exosome isolation and multiplex biomarker profiling from a single blood drop: Toward sample‐to‐answer liquid biopsy

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
A microfluidic nanodevice that analyses a single volume droplet of whole blood (10–50 microlitres (µL)) forms a fast and fully integrated exosome‐derived liquid biopsy. The closed system architecture involves plasma separation on chip, exosome enrichment by immunoaffinity and various size based, electrokinetic, acoustofluidic or hybridized strategies ...
Daniel Ejim Uti   +7 more
wiley   +1 more source

Mitogenomics of Culex pipiens Form Pipiens From the Turkish Black Sea Region Reveals Structural Conservation and Phylogenetic Complexity

open access: yesEcology and Evolution, Volume 16, Issue 8, August 2026.
Complete mitochondrial genomes of five Turkish Culex pipiens form pipiens isolates from the Black Sea region revealed highly conserved mitogenome architecture. Expanded comparisons across the broader Cx. pipiens complex showed that mitochondrial diversity was concentrated in selected loci and terminal regions associated with the A + T‐rich control ...
Ahsen Meliha Toroslu   +13 more
wiley   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1263-1275, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman   +5 more
wiley   +1 more source

How many tagged stones are needed to estimate the mean travel distance of sediment from tracer experiments in gravel‐bed rivers?

open access: yesEarth Surface Processes and Landforms, Volume 51, Issue 8, August 2026.
We propose a statistical model to analyse the impact of tracer sample size and tracer loss on the representativeness of samples in tracer studies in gravel‐bed rivers. Abstract Tagged particles (painted, with inserted magnets, RFID labelled) used as tracers have often been deployed in field experiments focused on tracking the displacement of river ...
Daniel Vázquez‐Tarrío   +3 more
wiley   +1 more source

Integrated Phytochemical and Pharmacological Investigation of Mentha aquatica L.: Anti‐Inflammatory, Analgesic, and Safety Evidence From In Vivo Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Mentha aquatica decocted extract contained mainly phenolic acids and showed a favorable oral safety profile in mice, with no significant subacute toxicity. Intraperitoneal administration caused dose‐dependent toxicity. The extract exhibited significant dose‐dependent anti‐inflammatory and analgesic activities in rodent models, supporting its potential ...
Meryem Tourabi   +14 more
wiley   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman   +6 more
wiley   +1 more source
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TRP channels

Current Opinion in Pharmacology, 2015
Evidence is accumulating on the role of transient receptor potential (TRP) channels, namely TRPV1, TRPA1, TRPV4 and TRPM8, expressed by C- and Aδ-fibres primary sensory neurons, in cough mechanism. Selective stimuli for these channels have been proven to provoke and, more rarely, to inhibit cough.
BENEMEI, SILVIA   +3 more
openaire   +2 more sources

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