Results 191 to 200 of about 32,080 (252)

Heart‐Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Selective purification of heart‐specific spinal and vagal sensory neurons by retrograde labeling and FACS purification showed enhanced spontaneous, optogenetic, and chemically stimulated Ca2+ activity. Transcriptomic profiling identified distinct ion channel and GPCR signatures in heart‐specific sensory neurons.
T. Akgul Caglar, Y. E. Kazci, Z. B. Durdu, S. Sahoglu Goktas, S. Bay, E. Vatandaslar, M. U. Turhan, G. Ozturk, E. Cagavi   +8 more
wiley   +1 more source

TRP channels: a provocative rationalization for local Ca²⁺ control in arterial tone development. [PDF]

Front Physiol
El-Lakany MA, Welsh DG.
europepmc   +1 more source

Microfluidic nanochips for rapid exosome isolation and multiplex biomarker profiling from a single blood drop: Toward sample‐to‐answer liquid biopsy

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
A microfluidic nanodevice that analyses a single volume droplet of whole blood (10–50 microlitres (µL)) forms a fast and fully integrated exosome‐derived liquid biopsy. The closed system architecture involves plasma separation on chip, exosome enrichment by immunoaffinity and various size based, electrokinetic, acoustofluidic or hybridized strategies ...
Daniel Ejim Uti, Esther Ugo Alum, Josephine E. Egbung, Waheeb Sami Aggad, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Manpreet Kaur, Kranti Kiran Reddy Ealla   +7 more
wiley   +1 more source

Mitogenomics of Culex pipiens Form Pipiens From the Turkish Black Sea Region Reveals Structural Conservation and Phylogenetic Complexity

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Complete mitochondrial genomes of five Turkish Culex pipiens form pipiens isolates from the Black Sea region revealed highly conserved mitogenome architecture. Expanded comparisons across the broader Cx. pipiens complex showed that mitochondrial diversity was concentrated in selected loci and terminal regions associated with the A + T‐rich control ...
Ahsen Meliha Toroslu, Alparslan Yildirim, Gokmen Zafer Pekmezci, Osman Ibis, Samba Deguene Diop, Batuhan Askim Arslanhan, Saffet Teber, Alina Denis Kizgin, Simge Sahin, Filiz Gunay, Nathan Burkett‐Cadena, Lindsay Campbell, Abdullah Inci, Barry Wilmer Alto   +13 more
wiley   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, Volume 11, Issue 4, Page 1263-1275, August 2026.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

Role of thermosensitive transient receptor potential (TRP) channels in thermal preference of male and female mice. [PDF]

J Therm Biol
Carstens MI, Mahroke A, Selescu T, Carstens E.   +3 more
europepmc   +1 more source

How many tagged stones are needed to estimate the mean travel distance of sediment from tracer experiments in gravel‐bed rivers?

Earth Surface Processes and Landforms, Volume 51, Issue 8, August 2026.
We propose a statistical model to analyse the impact of tracer sample size and tracer loss on the representativeness of samples in tracer studies in gravel‐bed rivers. Abstract Tagged particles (painted, with inserted magnets, RFID labelled) used as tracers have often been deployed in field experiments focused on tracking the displacement of river ...
Daniel Vázquez‐Tarrío, Thomas Dépret, Laro Incera‐Sañudo, Hervé Piégay   +3 more
wiley   +1 more source

Thermosensitive TRP Channels Are Functionally Expressed and Influence the Lipogenesis in Human Meibomian Gland Cells. [PDF]

Int J Mol Sci
Keller M, Mergler S, Li A, Zahn I, Paulsen F, Garreis F.   +5 more
europepmc   +1 more source

Integrated Phytochemical and Pharmacological Investigation of Mentha aquatica L.: Anti‐Inflammatory, Analgesic, and Safety Evidence From In Vivo Studies

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Mentha aquatica decocted extract contained mainly phenolic acids and showed a favorable oral safety profile in mice, with no significant subacute toxicity. Intraperitoneal administration caused dose‐dependent toxicity. The extract exhibited significant dose‐dependent anti‐inflammatory and analgesic activities in rodent models, supporting its potential ...
Meryem Tourabi, Khaoula Faiz, Rafik EL‐Mernissi, Bouchra Louasté, Mohammed Merzouki, Karima El‐Yagoubi, Layla Tahiri Elousrouti, Abdel‐Rhman Z. Gaafar, Mulugeta Tesemma, Esmael M. Alyami, Ohoud A. Alghamdi, Musa A. Said, Hina Ali, Badiaa Lyoussi, Elhoussine Derwich   +14 more
wiley   +1 more source

Thermal gradient ring for analysis of temperature-dependent behaviors involving TRP channels in mice. [PDF]

J Physiol Sci
Ujisawa T, Lei J, Kashio M, Tominaga M.
europepmc   +1 more source