Results 191 to 200 of about 65,940 (289)

Polarity of varicosity initiation in central neuron mechanosensation [PDF]

, 2017
Akhmanova, Amack, Andrieux, Baas, Barry, Barry, Barsukova, Benfenati, Bentley, Betz, Beyder, Bosc, Bu, Campàs, Caterina, Chen Gu, Cho, Christensen, Chung, Cosens, Couégnas, David Brody, Debanne, DeFord, Delmas, Deloulme, Eastwood, Elkin, Engler, Fournet, Franze, Gao, Gardner, Gibson, Gilmour, Grevesse, Gu, Gu, Gu, Gu, Gu, Guillaud, Harrington, Hasbani, Hemphill, Iwata, Jukkola, Jukkola, Kanayama, Kang, Koleske, Laurer, Lefèvre, Liedtke, Liedtke, Ligon, Lu, Luo, Margolis, Montell, Morris, Namba, Nikić, Peter Jukkola, Pirollet, Qian Wang, Reeves, Richard, Rishal, Ryskamp, Serrano, Shepherd, Shibasaki, Shitaka, Smith, Staal, Strotmann, Sánchez, Tang-Schomer, Thomas Esparza, Tseng, van Beuningen, Van Essen, Venkatachalam, Wang, Wang, Xu, Xu, Yang, Yi Zhao, Yuanzheng Gu, Zheng, Ziv, Árnadóttir   +93 more
core   +2 more sources

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

TRP channels and cancer modulation: a voyage beyond metabolic reprogramming, oxidative stress and the advent of nanotechnologies in targeted therapy. [PDF]

J Exp Clin Cancer Res
Giannaccari M, Florindi C, Bloise N, Moccia F, Lodola F, Visai L.   +5 more
europepmc   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

TRP Channels in Excitotoxicity. [PDF]

Neuroscientist
Zong P, Legere N, Feng J, Yue L.
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Cold-Sensing TRP Channels and Temperature Preference Modulate Ovarian Development in the Model Organism <i>Drosophila melanogaster</i>. [PDF]

Int J Mol Sci
Andreatta G, Montagnese S, Costa R.
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

TRP channels in hepatocellular carcinoma: integrative Mendelian randomization and multi-omics analyses highlight MCOLN3/TRPV4 as candidate dual-effect biomarkers. [PDF]

Hum Genomics
Xu Z, Pang C, Xu X.
europepmc   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source