Results 121 to 130 of about 1,267,413 (183)

TRPA1-Kationenkanäle [PDF]

open access: yes, 2019
The Transient Receptor Potential Ankyrin 1 (TRPA1) channel as a member of the TRP-family habors several so called ankyrin repeats in its amino-terminus. Moreover, the channel is composed of intracellular termini and six transmembrane domains with a pore ...
Kannler, Martina
core  

A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness?

open access: yes, 2015
© 2015, National Research Council of Canada. All rights reserved. Airway smooth muscle (ASM) contraction controls the airway caliber. Airway narrowing is exaggerated in obstructive lung diseases, such as asthma and chronic obstructive pulmonary disease ...
Ryu, MH   +4 more
core   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Pungent products from garlic activate the sensory ion channel TRPA1

open access: yes, 2005
Garlic belongs to the Allium family of plants that produce organosulfur compounds, such as allicin and diallyl disulfide (DADS), which account for their pungency and spicy aroma.
E. D. Hogestatt   +23 more
core   +1 more source

The TRPA1 Channel Amplifies the Oxidative Stress Signal in Melanoma. [PDF]

open access: yesCells, 2021
De Logu F   +11 more
europepmc   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1

open access: yes, 2014
Arachidonic acid (AA) and its derivatives are important modulators of cellular signalling. The transient receptor potential cation channel subfamily A, member 1 (TRPA1) is a cation channel with important functions in mediating cellular responses to ...
Peter McIntyre (324474)   +4 more
core  

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

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